@article{Lally:2017:10.1136/archdischild-2017-313321,
author = {Lally, PJ and Montaldo, P and Oliveira, V and Swamy, RS and Soe, A and Shankaran, S and Thayyil, S},
doi = {10.1136/archdischild-2017-313321},
journal = {Archives of Disease in Childhood. Fetal and Neonatal Edition},
pages = {F383--F387},
title = {Residual brain injury after early discontinuation of cooling therapy in mild neonatal encephalopathy},
url = {http://dx.doi.org/10.1136/archdischild-2017-313321},
volume = {103},
year = {2017}
}

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TY  - JOUR
AB  - We examined the brain injury and neurodevelopmental outcomes in a prospective cohort of 10 babies with mild encephalopathy who had early cessation of cooling therapy. All babies had MRI and spectroscopy within 2 weeks after birth and neurodevelopmental assessment at 2 years. Cooling was prematurely discontinued at a median age of 9 hours (IQR 5-13) due to rapid clinical improvement. Five (50%) had injury on MRI or spectroscopy, and two (20%) had an abnormal neurodevelopmental outcome at 2 years. Premature cessation of cooling therapy in babies with mild neonatal encephalopathy does not exclude residual brain injury and adverse long-term neurodevelopmental outcomes. This study refers to babies recruited into the MARBLE study (NCT01309711, pre-results stage).
AU  - Lally,PJ
AU  - Montaldo,P
AU  - Oliveira,V
AU  - Swamy,RS
AU  - Soe,A
AU  - Shankaran,S
AU  - Thayyil,S
DO  - 10.1136/archdischild-2017-313321
EP  - 387
PY  - 2017///
SN  - 1359-2998
SP  - 383
TI  - Residual brain injury after early discontinuation of cooling therapy in mild neonatal encephalopathy
T2  - Archives of Disease in Childhood. Fetal and Neonatal Edition
UR  - http://dx.doi.org/10.1136/archdischild-2017-313321
UR  - http://hdl.handle.net/10044/1/51211
VL  - 103
ER  - 

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