Therapy monitoringThe successful development and clinical application of therapy monitoring technologies requires multidisciplinary research spanning discovery science, translational research and clinical trials. There are key research challenges that need to be addressed across all of these domains, which will not only build our understanding about how therapies work in patients, but also inform clinical decision making. The Centre will support research that elucidates the mechanism of action of cancer therapeutics in patients, including the distribution, localisation and side effects of treatment and mechanisms of resistance. To improve clinical decision making, the Centre will support convergence science to develop tools and technologies allowing continuous monitoring of treatment response in patients, including in vivo and wearable sensor technologies and improved imaging-based modalities.