Organised by

Prof Annalisa Pastore
King's College London

Dr Yu Ye
Department of Brain Sciences, Imperial College London

Dr Michael Grange
Rosalind Franklin Institute

19-20 November 2024

The Stadium Room, Scale Space, White City, 58 Wood Lane, London W12 7RZ


Protein structure underpins function and dysfunction in molecular processes. Seventy years since the first protein and DNA structures, we are now for the first time able to consider studying the structure of molecules directly in situ and to correlate atomic resolution with information obtained at the cellular, tissue and organ levels.

In this two-day workshop, jointly hosted by Imperial College London, King's College London, and the Rosalind Franklin Institute, we will delve into recent advancements in the field and discuss how these novel technologies address key neuroscientific research challenges. There will be talks from world-leading experts who have made significant contributions to Structural Neuroscience, spanning atomic to organismal insights, as well as a poster session and drinks reception to catalyse collaborations. See the full list of speakers below.

Aims

  1. Discuss the frontier of structural biology in Neurosciences and Neurodegeneration, presenting the leading edge of current structural biology approaches to investigate neuronal function/misfunction.
  2. Reflect on the gaps in understanding that nascent structural approaches may address, and how a new era may be entered into that will permit a multiscale understanding of neuronal processes at different levels of resolution.

Any questions?

Please contact co-organiser Michael Grange (michael.grange@rfi.ac.uk) with any queries.

Speakers

Dr Alexandra Pacureanu

ESRF, the European Synchrotron
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Dr Benjamin Ryskeldi-Falcon

MRC Laboratory of Molecular Biology, Cambridge, UK
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Dr Claire Walsh

University College London
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2

Professor Sir David Klenerman

UK DRI at Cambridge
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Professor Elena Seiradake

University of Oxford
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Dr Janet Kumita

University of Cambridge
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3

Dr Judy Kim

The Rosalind Franklin Institute
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Dr Lisa Cabrita

University College London
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Professor Louis Serpell

University of Sussex
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4

Dr Naoko Mizuno

National Heart, Lung and Blood Institute
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Professor Perdita Barran

University of Manchester
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Professor Peter Cullen

University of Bristol
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5

Professor Radu Aricescu

MRC Laboratory of Molecular Biology
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Professor Rubén Fernández-Busnadiego

University Medical Centre, University of Göttingen
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Professor Sandra Ribeiro

Instituto de Investigação e Inovação em Saúde, University of Portugal
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6

Dr Sarah Mizielinska

UK DRI at King's College London
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Dr Sjors Scheres

MRC Laboratory of Molecular Biology
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Dr Tim Bartels

UK DRI at UCL
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