Critical care involves the care of the sickest patients in the hospital. Critically ill patients have usually been through a significant insult to their body (such as trauma, infection, burn) and have developed organ failure and require life-support. Critical Care is the largest theme bringing together clinicians and scientists from diverse backgrounds and includes collaborative research from hospitals throughout north-west London. Investigations range from evaluating biological mechanisms of organ failure through to the development of innovative technologies which allow the short-term and long-term support and recovery of organs.
Many people are exposed to the environment of an Intensive care unit (ICU) either personally or through a family member. It is often a life-changing event and our work aims to reduce this impact facilitating post-ICU recovery.
- Acute Respiratory Distress Syndrome (ARDS)
- Burn injury
- Extracorporeal life support
- Functional outcomes and health service research
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Journal articleBertok S, Wilson MR, Dorr AD, et al., 2011,
Journal articleCampbell L, Shrosbree J, Ibrahim F, et al., 2011,
Late HIV diagnosis is a major risk factor for intensive care unit (ICU) admission in HIV-positive patients, HIV MEDICINE, Vol: 12, Pages: 52-52, ISSN: 1464-2662
Journal articleTatham K, Hughes-Roberts Y, Davies S, et al., 2010,
Journal articleWilson MR, O'Dea KP, Dorr AD, et al., 2010,
Journal articleGrover S, Vizcaychipi MP, Ma D,
Anaesthetic management of patients with acute spinal injury, Anesthesiology Research and Practice
Journal articleVizcaychipi MP, Keays R, 2010,
Anaesthesia and intensive care in HIV patients, http://www.sciencedirect.com/science/journal/14720299, Vol: 11, Pages: 37-41
HIV is a blood-borne viral infection that has implications for anaesthesia and intensive care. HIV was initially described in 1981 and it was associated with very high mortality when patients were admitted to intensive care. There have been several advances in the management of HIV patients over the past decades. Antiretroviral therapy is targeted to individuals with high viral load and or symptoms apart from CD4 count. This approach not only helps to keep patients free of symptoms for a long period of time but also contributes to better survival duration and outcome when patients are admitted to intensive care. It has been a challenge to anaesthetize this group of patients because drug interaction is a potential risk and regional anaesthesia may be potentially hazardous if a cautious and exhaustive neurological examination is not performed. New generations of drugs may be more effective and, hopefully, have fewer side effects. There will be more patients in long-term remission from the disease but its implications are still unclear. This disease is no longer rare and clinicians need to have a working knowledge of its presentation and management.
Journal articleGordon AC, Russell JA, Walley KR, et al., 2010,
Journal articleHandy JM, Scott AJ, Cross AM, et al., 2010,
Conference paperFletcher M, Boshier P, Smolenski RT, et al., 2009,
Journal articleWilson MR, O'Dea KP, Zhang D, et al., 2009,
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