Critical care wardCritical care involves the care of the sickest patients in the hospital. Critically ill patients have usually been through a significant insult to their body (such as trauma, infection, burn) and have developed organ failure and require life-support. Critical Care is the largest theme bringing together clinicians and scientists from diverse backgrounds and includes collaborative research from hospitals throughout north-west London. Investigations range from evaluating biological mechanisms of organ failure through to the development of innovative technologies which allow the short-term and long-term support and recovery of organs. 

Many people are exposed to the environment of an Intensive care unit (ICU) either personally or through a family member. It is often a life-changing event and our work aims to reduce this impact facilitating post-ICU recovery.

Research themes:


Citation

BibTex format

@article{Zhao:2016:10.1097/ALN.0000000000001128,
author = {Zhao, H and Mitchell, S and Koumpa, S and Cui, YT and Lian, Q and Hagberg, H and Johnson, M and Takata, M and Ma, D and Ma, D and Takata, M and Johnson, M and Zhao, H},
doi = {10.1097/ALN.0000000000001128},
journal = {Anesthesiology},
pages = {180--192},
title = {Heme Oxygenase-1 mediates neuro-protection conferred by argon in combination with hypothermia in neonatal hypoxia-ischemia brain injury},
url = {http://dx.doi.org/10.1097/ALN.0000000000001128},
volume = {125},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Argon–hypothermia treatment reduced both neuronal death in an in vitro neuronal culture model and brain infarct size in an in vivo rat model of neonatal asphyxia. The protective effects of argon–hypothermia involve both inhibition of apoptosis and neuroinflammation mechanisms and activation of cell survival pathways.
AU - Zhao,H
AU - Mitchell,S
AU - Koumpa,S
AU - Cui,YT
AU - Lian,Q
AU - Hagberg,H
AU - Johnson,M
AU - Takata,M
AU - Ma,D
AU - Ma,D
AU - Takata,M
AU - Johnson,M
AU - Zhao,H
DO - 10.1097/ALN.0000000000001128
EP - 192
PY - 2016///
SN - 1528-1175
SP - 180
TI - Heme Oxygenase-1 mediates neuro-protection conferred by argon in combination with hypothermia in neonatal hypoxia-ischemia brain injury
T2 - Anesthesiology
UR - http://dx.doi.org/10.1097/ALN.0000000000001128
UR - http://hdl.handle.net/10044/1/30175
VL - 125
ER -