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SUMMARY:Rules and roles of spike timing-dependent plasticity at hippocampal
  synapses
DESCRIPTION:For information about the speaker\, please visit his webpage. 
  \nAbstract\nSynaptic plasticity is a leading candidate for a cellular me
 chanism underlying learning and memory. Spike timing-dependent plasticity 
 (STDP) is a physiologically plausible form of synaptic plasticity in which
  the order and precise timing of pre- and postsynaptic spikes determine th
 e sign of synaptic change. In its canonical form\, pre–before-post spike
  pairings induce timing-dependent long-term potentiation (t-LTP) whereas p
 ost–before-pre pairings induce long-term depression (t-LTD). In this sem
 inar I will describe how the specific rules of synaptic plasticity vary de
 pending on the spatio-temporal activity in the network and how they are al
 tered by neuromodulators\, including the reward-related signalling molecul
 e dopamine. We will also discuss possible computational and cognitive impl
 ications of these modifications to STDP rules. 
URL:https://www.imperial.ac.uk/events/103797/rules-and-roles-of-spike-timin
 g-dependent-plasticity-at-hippocampal-synapses/
DTSTART;TZID=Europe/London:20151009T123000
DTEND;TZID=Europe/London:20151009T133000
LOCATION:United Kingdom
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