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UID:c4f32f1eea93efbc719580bfd2535474
DTSTAMP:20261028T032047Z
SUMMARY:Mathematical Physics Seminar 9/3 – Dr David Zwicker – Controlli
 ng phase separation inside biological cells
DESCRIPTION:Mathematical Physics Seminar 23/3 – Dr David Zwicker – Cont
 rolling phase separation inside biological cells\nAbstract: Biological cel
 ls consist of thousands of different biomolecules that move and react rapi
 dly. Yet\, cells display robust behavior\, partly because they separate mo
 lecules into distinct compartments. It is now clear that many small compar
 tments are droplets formed via phase separation\, but we do not yet unders
 tand how cells control these droplets. In this talk\, I will discuss two s
 pecific control mechanisms. First\, I will introduce a novel method to stu
 dy phase separation in multicomponent fluids. I will use it to show how ce
 lls can adjust molecular interactions over evolutionary time scales to for
 m multiple different types of droplets robustly. Second\, I will turn to n
 on-equilibrium systems and demonstrate that driven chemical reactions prov
 ide a powerful way to regulate droplets. These reactions influence the phy
 sical properties of droplet components and thus their phase behavior. I wi
 ll show that such active droplets can stably coexist with controlled size 
 and position. These two examples demonstrate how cells can leverage phase 
 separation to control their spatial structure over relevant time scales.\n
  
URL:https://www.imperial.ac.uk/events/145528/mathematical-physics-seminar-9
 -3-dr-david-zwicker/
DTSTART;TZID=Europe/London:20220309T150000
DTEND;TZID=Europe/London:20220309T160000
LOCATION:United Kingdom
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