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SUMMARY:Biomathematics seminar – Marina Escalera Zamudio (UCL)
DESCRIPTION:From Viral Evolution to Public Health: Big Data for Outbreak 
 Preparedness\n\nViruses with rapid mutation rates provide powerful model s
 ystems for studying evolutionary processes in near real time. However\, vi
 ral evolution is not purely stochastic\, as trade-offs imposed by protein 
 structure\, host-mediated selection\, and transmission dynamics limit the 
 space of viable mutations\, leading to recurrent and sometimes predictable
  evolutionary and epidemiological outcomes. The unprecedented availability
  of viral genomic data has transformed our ability to reconstruct virus ev
 olution\, from quantifying the constraints that shape adaptive trajectorie
 s to tracking viral spread across time and space.\n\nIn this talk\, I will
  outline how my research moves from fundamental evolutionary theory to the
  analysis of viral spread patterns with applications in genomic epidemiolo
 gy and outbreak preparedness. By integrating large-scale genomic data with
  computational modelling\, I examine how selection\, drift\, and biologica
 l constraints jointly shape viral diversification and epidemic dynamics. F
 inally\, I will draw on examples from my projects in Mexico\, where genomi
 c surveillance and evolutionary inference have helped characterise the int
 roduction\, spread\, and diversification of multiple viral pathogens. Thes
 e case studies highlight the importance of shared evolutionary drivers sha
 ping recurrent epidemic emergence and illustrate how theory-informed frame
 works can support public health decision-making.
URL:https://www.imperial.ac.uk/events/206434/biomathematics-seminar-marina-
 escalera-zamudio-ucl/
DTSTART;TZID=Europe/London:20260302T130000
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LOCATION:1004\, Blackett Building\, South Kensington Campus\, Imperial Coll
 ege London\, London\, SW7 2AZ\, United Kingdom
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