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SUMMARY:Biomathematics Seminar – Philip Greulich (University of Southampt
 on)
DESCRIPTION:Title: “Quantitative Modelling in biology and beyond: what’
 s the point?”\nMany of us do ‘quantitative modelling’ in one form or
  another. But why are we actually doing it\, apart from the satisfaction a
 chieved from finding a nice and fitting model? What is the scientific purp
 ose of mathematical modelling and what do we get out of it\, from a utilit
 arian point of view? Most of you will be convinced of its benefits\, but c
 an you also convince your experimentalist collaborators?\nIn this talk\, I
  wish to discuss the applications of modelling in very broad strokes\, its
  purposes\, and under which circumstances it does provide a lot of ‘adde
 d value’ to scientific research (in conjunction with experiments) and al
 so\, under which circumstances it doesn’t. I will exemplify this on some
  works using mathematical modelling in stem cell biology\, although the ba
 sic principles stay valid beyond that. In particular\, I wish to address c
 ommon pitfalls\, in which completely wrong models fit data perfectly (not 
 just because of overfitting)\, which may confound scientific conclusions s
 ubstantially. The latter may occur due to “universality”\, which can l
 ead of erroneous model fitting\, but at the same time is the reason that (
 mechanistic) quantitative modelling can work at all.
URL:https://www.imperial.ac.uk/events/200247/biomathematics-seminar-philip-
 greulich-university-of-southampton/
DTSTART;TZID=Europe/London:20251013T130000
DTEND;TZID=Europe/London:20251013T140000
LOCATION:HXLY 642\, Huxley Building\, South Kensington Campus\, Imperial Co
 llege London\, London\, SW7 2AZ\, United Kingdom
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