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  • Journal article
    Blaker JJ, Lee K-Y, Bismarck A, 2011,

    Hierarchical Composites Made Entirely from Renewable Resources

    , JOURNAL OF BIOBASED MATERIALS AND BIOENERGY, Vol: 5, Pages: 1-16, ISSN: 1556-6560
  • Book chapter
    Lee K-Y, Bismarck A, 2011,

    Assessing the moisture uptake behaviour of natural fibres

    , Interface Engineering of Natural Fibre Composites for Maximum Performance, Editors: Zafeiropoulos, Publisher: Elsevier, ISBN: 9780857092281

    One of the major reasons for composite failure is a breakdown of the bond between the reinforcement fibres and the matrix. When this happens, the composite loses strength and fails.
  • Journal article
    Ege MJ, Mayer M, Normand A-C, Genuneit J, Cookson WOCM, Braun-Fahrlaender C, Heederik D, Piarroux R, von Mutius Eet al., 2011,

    Exposure to Environmental Microorganisms and Childhood Asthma

    , NEW ENGLAND JOURNAL OF MEDICINE, Vol: 364, Pages: 701-709, ISSN: 0028-4793
    • Cite
    • Citations: 1207
  • Journal article
    Bilsborough GD, Runions A, Barkoulas M, Jenkins HW, Hasson A, Galinha C, Laufs P, Hay A, Prusinkiewicz P, Tsiantis Met al., 2011,

    Model for the regulation of <i>Arabidopsis thaliana</i> leaf margin development

    , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 108, Pages: 3424-3429, ISSN: 0027-8424
    • Cite
    • Citations: 309
  • Journal article
    Holt RJ, Zhang Y, Binia A, Dixon AL, Vandiedonck C, Cookson WO, Knight JC, Moffatt MFet al., 2011,

    Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).

    , Journal of Allergy and Clinical Immunology, Vol: 127, Pages: 1054-1062.e2, ISSN: 0091-6749

    Asthma is a common, chronic inflammatory airway disease of major public health importance with multiple genetic determinants. Previously, we found by positional cloning that PHD finger protein 11 (PHF11) on chromosome 13q14 modifies serum immunoglobulin E (IgE) concentrations and asthma susceptibility. No coding variants in PHF11 were identified.ObjectiveHere we investigate the 3 single nucleotide polymorphisms (SNPs) in this gene most significantly associated with total serum IgE levels—rs3765526, rs9526569, and rs1046295—for a role in transcription factor binding.MethodsWe used electrophoretic mobility shift assays to examine the effect of the 3 SNPs on transcription factor binding in 3 cell lines relevant to asthma pathogenesis. Relative preferential expression of alleles was investigated by using the allelotyping method.ResultsElectrophoretic mobility shift assays show that rs1046295 modulates allele-specific binding by the octamer-binding transcription factor 1 (Oct-1). Analysis of the relative expression levels of the 2 alleles of this SNP in heterozygous individuals showed a modest, but highly significant (P = 6.5 × 10−16), preferential expression of the A allele consistent with a functional role for rs1046295.ConclusionThese results suggest a mechanism by which rs1046295 may act as a regulatory variant modulating transcription at this locus and altering asthma susceptibility.
  • Journal article
    Hardwick KA, Fiedler P, Lee LC, Pavlik B, Hobbs RJ, Aronson J, Bidartondo M, Black E, Coates D, Daws MI, Dixon K, Elliott S, Ewing K, Gann G, Gibbons D, Gratzfeld J, Hamilton M, Hardman D, Harris J, Holmes PM, Jones M, Mabberley D, Mackenzie A, Magdalena C, Marrs R, Milliken W, Mills A, Lughadha EN, Ramsay M, Smith P, Taylor N, Trivedi C, Way M, Whaley O, Hopper SDet al., 2011,

    The role of botanic gardens in the science and practice of ecological restoration.

    , Conservation Biology, ISSN: 1523-1739

    Many of the skills and resources associated with botanic gardens and arboreta, including plant taxonomy, horticulture, and seed bank management, are fundamental to ecological restoration efforts, yet few of the world's botanic gardens are involved in the science or practice of restoration. Thus, we examined the potential role of botanic gardens in these emerging fields. We believe a reorientation of certain existing institutional strengths, such as plant-based research and knowledge transfer, would enable many more botanic gardens worldwide to provide effective science-based support to restoration efforts. We recommend botanic gardens widen research to include ecosystems as well as species, increase involvement in practical restoration projects and training practitioners, and serve as information hubs for data archiving and exchange.
  • Journal article
    Mills RE, Walter K, Stewart C, Handsaker RE, Chen K, Alkan C, Abyzov A, Yoon SC, Ye K, Cheetham RK, Chinwalla A, Conrad DF, Fu Y, Grubert F, Hajirasouliha I, Hormozdiari F, Iakoucheva LM, Iqbal Z, Kang S, Kidd JM, Konkel MK, Korn J, Khurana E, Kural D, Lam HYK, Leng J, Li R, Li Y, Lin C-Y, Luo R, Mu XJ, Nemesh J, Peckham HE, Rausch T, Scally A, Shi X, Stromberg MP, Stuetz AM, Urban AE, Walker JA, Wu J, Zhang Y, Zhang ZD, Batzer MA, Ding L, Marth GT, McVean G, Sebat J, Snyder M, Wang J, Ye K, Eichler EE, Gerstein MB, Hurles ME, Lee C, McCarroll SA, Korbel JOet al., 2011,

    Mapping copy number variation by population-scale genome sequencing

    , NATURE, Vol: 470, Pages: 59-65, ISSN: 0028-0836
    • Cite
    • Citations: 792
  • Journal article
    Fainleib A, Grigoryeva O, Youssef B, Saiter JM, Bismarck Aet al., 2011,

    Modification of polycyanurate network by reactive rubbers with hydrazide, acylhydrazone and isocyanate terminal groups

    , Pages: 321-352

    First, chemical interactions between hydrazide, acylhydrazone and isocyanate groups from one side with cyanate groups from other side have been studied using methods of FTIR spectroscopy and NMR 1H analysis. The formation of the substituted cyanurate (triazine) cycles has been found. These results were confirmed on polymer systems at modification of polycyanurate network (PCN) by reactive rubbers, possessing the above mentioned functional groups, where the chemical reactions found led to incorporation of the rubbers into the PCN network. The partial chemical incorporation of the rubber modifiers' fragments into the PCN network structure has been found. The structure of the final hybrid networks was found to be depended on reactivity of the rubber modifier's functional groups toward cyanate groups and the modifier content in the system. It has been established that the unreacted part of the modifier forms the own separated microphase. The most pronounced two phase structure has been observed for OIDAH rubber with the lowest reactivity towards cyanate groups of the growing PCN network. © 2010 Nova Science Publishers, Inc. All rights reserved.
  • Journal article
    Quero F, Nogi M, Lee K-Y, Vanden Poel G, Bismarck A, Mantalaris A, Yano H, Eichhorn SJet al., 2011,

    Cross-Linked Bacterial Cellulose Networks Using Glyoxalization

    , ACS APPLIED MATERIALS & INTERFACES, Vol: 3, Pages: 490-499, ISSN: 1944-8244
  • Journal article
    Garner TWJ, Rowcliffe JM, Fisher MC, 2011,

    Climate change, chytridiomycosis or condition: an experimental test of amphibian survival

    , GLOBAL CHANGE BIOLOGY, Vol: 17, Pages: 667-675, ISSN: 1354-1013
    • Cite
    • Citations: 68

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