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  • Journal article
    Papadopoulou E, Sykes DL, Goeminne P, Machado A, Marghlani D, McNeil L, Norwell J, Paixão C, Shoemark A, Boyd J, Ekkelenkamp M, Thee S, Shah Aet al., 2025,

    Patients’ perspectives on antimicrobial resistance in chronic respiratory disease: an AMR-Lung – European Lung Foundation global patient survey

    , ERJ Open Research, ISSN: 2312-0541

    Background:Antimicrobial resistance (AMR) represents a significant global health threat, particularly for people with chronic respiratory diseases. However, their experiences, knowledge, priorities and concerns have not been comprehensively assessed. This study aimed to gauge patients’ perspectives of AMR burden in chronic respiratory disease.Methods:An anonymous web-based patient survey was developed by AMR-Lung ERS Clinical Research Collaboration and members from the European Lung Foundation patient advisory groups, consisting of 39 questions, translated into 20 languages and held online over a 2-month period. Multivariable logistic regression analyses were used to explore disease-specific burden and factors potentially affecting AMR across different healthcare settings.Results:Among 2012 respondents from 57 countries on all 6 continents, 30.7% recalled having an AMR-associated infection, while 12.6% perceived their last antimicrobial course as ineffective. 30.5% received long-term prophylactic antimicrobials, with 44.6% of them recalling an AMR-associated infection. 17.6% reported antimicrobial use without medical prescription, while 9.5% perceived prescriptions as delayed. Respondents recognised mostly their healthcare professionals as an information source regarding AMR, but 27% were unaware of AMR prior to the survey. Patients from high-income countries were more likely to be knowledgeable about AMR, and less inclined to use antimicrobials without prescription and to perceive them as ineffective. Respondents overwhelmingly viewed AMR as a personal (76.4%) and global (79.6%) threat.Conclusions:This global large-scale survey ascertains for the first time the high AMR burden from the perspective of people with chronic respiratory diseases, accentuating the need to promote AMR awareness, judicious antimicrobial use, and accessibility to quality healthcare.

  • Journal article
    Shah A, Kosmidis C, 2025,

    Aspergillus-related lung disease: a wake-up call to navigate complexity in a neglected condition.

    , Thorax, Vol: 80, Pages: 1-2
  • Journal article
    Howard NOA, Rodriguez-Morelos VH, Allen L, Chinoruma P, Cohen LD, Hoysted GA, Jungblut AD, Lamb I, Moeskjaer S, Pinzari F, Prout J, Stanley CE, Ton J, Watts A, Williams A, Daniell T, Wanke A, Schornack S, Pressel S, Field KJet al., 2025,

    What's in a name? The case for standardized nomenclature for mutualistic Mucoromycotina ‘fine root endophytes’

    , Journal of Experimental Botany, ISSN: 0022-0957

    Arbuscular mycorrhizal (AM) fungi are a near-ubiquitous group of plant symbiotic fungi and have been the focus of much mycorrhizal research over the last 60 years (Koide and Mosse, 2004). However, a lesser known group of mycorrhizal fungi, the Mucoromycotina ‘fine root endophytes’ (MFRE), have garnered increasing research interest in recent years. This early branching lineage of fungi (Bidartondo et al., 2011; Field et al., 2015) was recently reclassified as belonging to the subphylum Mucoromycotina (Orchard et al., 2017a) rather than the Glomeromycotina which encompasses the AM fungi (or ‘coarse root endophytes’). Considering the rapidly growing interest in fine root endophytes, the use of a consistent nomenclature is becoming an important issue for the research community. Here, we summarize the background literature and recent discussion from the 12th International Conference on Mycorrhiza (ICOM12; 4–9 August 2024, Manchester, UK), proposing a standardized and cohesive terminology for this group of enigmatic, though widespread, endomycorrhizal fungi.

  • Journal article
    Feary J, Yu Y, Kabir T, Schofield S, Bevan A, Askinyte V, Honan K, Emirali L, Rubbi A, Willis AE, Cullinan P, Anand S, Martins LMet al., 2025,

    Assessment of cancer biomarkers in the Grenfell firefighter cohort study

    , SCIENTIFIC REPORTS, Vol: 15, ISSN: 2045-2322
  • Conference paper
    Tiddens H, Makani P, Bonte M, Cregan R, Rea D, Persaud T, Twomey E, McGrane S, Caudri D, Dodd JD, McKone EF, Semple T, Davies JC, McNally Pet al., 2025,

    Changes in Low Attenuation Regions and Arterial and Venous Blood Volume Distribution in Response to CFTR Modulator Therapy in People With Cystic Fibrosis

    , International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X
  • Journal article
    Gnaim R, Dyer PS, Ledesma-Amaro R, 2025,

    Fusarium-based mycoprotein: advancements in the production of sustainable meat substitutes

    , Trends in Food Science & Technology, Vol: 159, ISSN: 0924-2244

    BackgroundPursuing sustainable and nutritious food has positioned Fusarium-based mycoprotein as a promising solution to the environmental and health challenges posed by some traditional agricultural practices and types of food. As consumer awareness grows and the demand for alternative proteins increases, Fusarium species offer a scalable, environmentally friendly, and nutritious option to address these issues.Scope and approachThis review delves into the unique characteristics of certain Fusarium species, which make them ideal candidates for mycoprotein production. It explores advancements in fermentation technologies, metabolic engineering, and process optimisation that have; enhanced production efficiency and product quality. The review also examines the technical, economic, and regulatory challenges hindering large-scale production and commercialisation, such as the high costs of fermentation, the need for robust; regulatory frameworks, and consumer acceptance. Furthermore, it highlights the significance of interdisciplinary collaboration and continuous innovation to overcome these challenges and unlock the full potential of Fusarium-based mycoprotein.Key findings and conclusionsBy synthesizing recent research and market trends, this review provides a comprehensive understanding of the potential of Fusarium-based mycoprotein to contribute to a sustainable and resilient food system. It emphasizes the need for targeted research, streamlined production processes, and strategic partnerships to advance its development and adoption, ultimately shaping the future of sustainable nutrition.

  • Journal article
    Howlett P, Szram J, Feary J, 2025,

    Occupational lung disease: what the general physician needs to know

    , Clinical Medicine, Vol: 25, ISSN: 1470-2118

    Occupational exposures are a common and preventable cause of lung disease. About one in six cases of chronic obstructive pulmonary disease (COPD) and asthma worldwide are related to work.Early recognition of occupational lung disease improves outcomes. Doctors should ask about work history in patients with respiratory symptoms. This educational review article briefly outlines key clinical features, relevant to the general physician, of common occupational lung diseases seen in the UK. These conditions include work-related asthma, pneumoconioses, hypersensitivity pneumonitis and COPD.Referral to a specialist is recommended when an occupational cause is suspected. Most occupational lung diseases are preventable with adequate workplace safety measures and early medical attention.

  • Journal article
    Bush A, Brochard LJ, Han MK, Chotirmall SH, Harhay MO, Martinez FJet al., 2025,

    Airtime for the Airway

    , AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 211, Pages: 670-671, ISSN: 1073-449X
  • Journal article
    Gottlieb J, Vos R, Jaksch P, Hellemons M, Holm AM, Morlacchi LC, Magnusson J, Moralejo RA, Mora-Cuesta VM, Ennekes V, Reed A, Vignaux CMD, Hettich I, Bennett D, Hecker M, Wald A, Guk S, Skride A, Nolde A, Knoop C, Meloni F, Tikkanen J, Larsson H, Tissot A, Riddell P, Le Pavec J, Perch M, Renaud-Picard B, Carlier FM, Mueller V, Parmar J, Havlin J, Laporta R, Chuurmans MM, Harlander M, Zenglen S, Brugiere O, Kneidinger N, Fisher A, Saez-Gimenez Bet al., 2025,

    Chronic lung allograft dysfunction after lung transplantation: prevention, diagnosis and treatment in 44 European centres

    , ERJ OPEN RESEARCH, Vol: 11
  • Journal article
    Waterer GW, Chotirmall SH, 2025,

    Dancing with DPP-1: The Inflammatory Tango of Bronchiectasis

    , AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 211, Pages: 678-679, ISSN: 1073-449X

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