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• Journal article
  Nicholson AG, Adegunsoye A, Piciucchi S, Hariri LP, Khor YH, Wijsenbeek MS, Wells AU, Sharma A, Cooper WA, Antoniou K, Borie R, Fabre A, Inoue Y, Johannson KA, Johkoh T, Kawano-Dourado L, Kazerooni E, Maher TM, Molyneaux PL, Protti R, Ravaglia C, Renzoni EA, Saito-Koyama R, Sverzellati N, Walsh SLF, Wolters PJ, Yang S-R, Travis WD, Ryerson CJet al., 2026,

  Reply: From the authors of the ERS/ATS statement on the international multidisciplinary classification of the interstitial pneumonias.

  , Eur Respir J, Vol: 67
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• Journal article
  Martin AK, Mercier O, Bottiger B, Cypel M, Fessler J, Gomez-De-Antonio D, Levvey B, Lyster H, Nasir B, Sanchez M, Wille K, Fritz AV, Gelzinis T, Hoetzenecker K, Dave K, Lindstedt S, Marczin N, Wilkey B, Schecter M, Walsh J, Morrissey O, Landry C, Saatee S, Kotecha S, Behr J, Kukreja J, Dellgren G, Reed AKet al., 2026,

  ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part III: Postoperative Considerations

  , JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 45, Pages: e63-e81, ISSN: 1053-2498
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  • Citations: 3
• Journal article
  Worland AM, Xu VA, Duran MF, Gitman P, Hunter-Cevera K, Klemm C, Sun Y, Sanchis DR, Ledesma-Amaro R, Pomraning KR, Tanjore D, Blenner M, Tang YJet al., 2026,

  Staying productive under pressure: systems evaluations of β-carotene production in Yarrowia lipolytica under continuous fermentation.

  , Trends Biotechnol, Vol: 44, Pages: 154-169

  Scaling biomanufacturing from laboratory to industrial scale poses significant challenges, especially for continuous fermentation. This study investigates these challenges using a β-carotene-producing Yarrowia lipolytica strain. Through fermentation experiments and proteomics, we have assessed how fermentation modes, carbon sources, dissolved O2, and media composition influence long-term bioproduction. In shaking flask subcultures, the strain maintained β-carotene production for over ~30 generations. However, in continuous fermentations, subpopulation shifted toward faster-growing low-producers, leading to significant production losses within just ~18 growth generations. This process was accelerated by O2 limitation and high bioreactor dilution rates. Using canola oil as a carbon source increases population heterogeneity but enhances β-carotene biosynthesis and prolongs production compared with glucose-based media. Kinetic modeling suggests that strains optimized for the highest production in laboratory settings may be less robust in industrial environments, where suboptimal yet faster-growing variants gain a competitive edge under prolonged stress and ultimately shape overall continuous fermentation performance.

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• Journal article
  Reed AK, Mercier O, Behr J, Dave K, Dellgren G, Kotecha S, Kukreja J, Landry C, Levvey B, Lyster H, Morrissey O, Saatee S, Sanchez M, Schecter M, Walsh J, Virginia A, Gelzinis TA, Hoetzenecker K, Lindstedt S, Marczin N, Wilkey BJ, Fessler J, Bottiger B, Wille K, Nasir BS, Gomez-De-Antonio D, Cypel M, Martin AKet al., 2026,

  ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part I: Preoperative Considerations

  , JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 45, Pages: e1-e34, ISSN: 1053-2498
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  • Citations: 1
• Journal article
  Martin AK, Mercier O, Bottiger B, Cypel M, Fessler J, Gomez-De-Antonio D, Levvey B, Lyster H, Nasir B, Sanchez M, Dclinpsy, Wille K, Fritz AV, Gelzinis T, Hoetzenecker K, Dave K, Lindstedt S, Marczin N, Wilkey B, Schecter M, Walsh J, Morrissey O, Landry C, Saatee S, Kotecha S, Behr J, Kukreja J, Dellgren G, Reed AKet al., 2026,

  Author Insights on the ISHLT Perioperative Utilization of ECLS In Lung Transplantation Consensus

  , JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 45, Pages: 1-4, ISSN: 1053-2498
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• Journal article
  Swamy R, Völtz LR, Xiong S, Berglund L, Bismarck A, Oksman Ket al., 2025,

  Approach to Sustainable Fibers from Spent Mushroom Substrate for Future All-Natural-Materials

  , ACS Sustainable Chemistry & Engineering, ISSN: 2168-0485
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• Journal article
  Agarwal R, Chotirmall SH, Chalmers JD, 2025,

  Allergic bronchopulmonary aspergillosis and Aspergillus-related airway diseases in bronchiectasis: a narrative review

  , Journal of Thoracic Disease, Vol: 17, Pages: 11501-11519, ISSN: 2072-1439

  Background and Objective: Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity disorder classically associated with asthma or cystic fibrosis (CF). Recent guidelines have broadened the scope of ABPA to include patients with bronchiectasis, even without underlying asthma or CF. Beyond ABPA, other Aspergillus-associated phenotypes, namely Aspergillus sensitization (AS), chronic Aspergillus infection (CAI), and Aspergillus bronchitis, are increasingly recognized as clinically relevant entities in bronchiectasis. This review outlines the immunological, radiological, and clinical characteristics of ABPA in bronchiectasis, describes the prevalence and spectrum of Aspergillus-related airway disease, and presents a contemporary diagnostic and therapeutic framework based on the 2024 International Society for Human and Animal Mycology (ISHAM) ABPA Working Group (AWG) guidelines. Methods: We searched PubMed since its inception to June 6, 2025. The keywords included “ABPA” OR “allergic bronchopulmonary aspergillosis” OR “bronchiectasis”. Inclusion criteria focused on original studies in English involving bronchiectasis and ABPA, published in peer-reviewed journals. Key Content and Findings: ABPA, AS, and CAI represent a continuum of fungal airway disease shaped by host immune responses. ABPA affects approximately 4% of bronchiectasis patients and may be both a cause and consequence of bronchiectasis. AS and CAI collectively may affect up to 30% of bronchiectasis patients and are independently associated with worse clinical outcomes, including higher bronchiectasis severity scores and increased exacerbation rates. A. fumigatus-immunoglobulin E (IgE) remains the cornerstone of ABPA screening, with international guidelines advocating routine testing in all bronchiectasis patients at diagnosis. ABPA is diagnosed when AS coexists with supportive immunological and radiological features. Management includes systemic glucocorticoids o

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• Journal article
  Polineni D, Davies JC, Boyd AC, Donaldson SH, Gill DR, Griesenbach U, Hyde SC, Jain R, McLachlan G, Mall MA, Alton EWFWet al., 2025,

  Potential gene therapies for cystic fibrosis: a plain language summary for non-specialists and the lay community

  , Future Rare Diseases, Vol: 5
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• Journal article
  Moron-Ortiz A, Ferrando-Marco M, Leon-Vaz A, Leon R, Mapelli-Brahm P, Barkoulas M, Martinez M, Jesus Aet al., 2025,

  Effects of lutein, phytoene and carotenoid-rich microalgal extracts on the epidermis of <i>Caenorhabditis elegans</i>

  , FOOD CHEMISTRY, Vol: 497, ISSN: 0308-8146
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• Journal article
  Thng KX, Mac Aogáin M, Chotirmall SH, 2025,

  Fungal-Associated Endotypes as a Treatable Trait in Bronchiectasis.

  , Pulm Ther

  Emerging evidence demonstrates the evolving role of fungi in the pathophysiology and disease progression observed in bronchiectasis. Fungal-associated traits are linked to disease severity, exacerbation frequency and airway inflammation. Structural abnormalities and impaired mucociliary clearance, characteristic of bronchiectasis, predispose to fungal colonisation, with subsequent immunopathogenic responses dependent on underlying host immunity. The diagnosis of fungal infection remains challenging in clinical settings, owing to the limitations of existing diagnostic modalities; however, the development of culture-independent molecular techniques shows promise. The use of next-generation sequencing has significantly advanced our understanding of the fungal microbiome in bronchiectasis, identifying fungi that are challenging to culture. Integrative microbiomics further elucidates the intricate and dynamic role of fungi in relation to other microbial kingdoms, and across distant organs such as the gut, revealing important relationships with bacterial pathogens including Pseudomonas aeruginosa. Airway inflammatory profiling has shown fungal-associated inflammatory endotypes which may serve as treatable traits. Environmental influences on fungi and bronchiectasis-exacerbated by air pollution and climate change-underscore the key role of the exposome in fungal-associated endotypes in bronchiectasis. This review outlines the clinical significance of fungi in bronchiectasis, the current diagnostic and treatment challenges, and emerging fungal-associated endotypes in the context of environmental influence on disease.

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