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Journal articleBismarck A, Schulz E, 2003,
Adhesion and friction behavior between fluorinated carbon fibers and poly (vinylidene fluoride)
, JOURNAL OF MATERIALS SCIENCE, Vol: 38, Pages: 4965-4972, ISSN: 0022-2461- Author Web Link
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- Citations: 31
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Journal articleFernández-Martínez J, Brown CV, Díez E, et al., 2003,
Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC
, JOURNAL OF MOLECULAR BIOLOGY, Vol: 334, Pages: 667-684, ISSN: 0022-2836- Author Web Link
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- Citations: 65
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Journal articleCookson W, 2003,
July 1957 (from the trifler) section: Rock -Drill
, Agenda, Vol: 39, ISSN: 0002-0796 -
Conference paperHilliard TN, Madden N, Nicholson AG, et al., 2003,
Airway inflammation and remodelling in children with cystic fibrosis
, Winter Meeting of the British Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 64-64, ISSN: 0040-6376 -
Journal articleTanzer MM, Arst HN, Skalchunes AR, et al., 2003,
Global nutritional profiling for mutant and chemical mode-of-action analysis in filamentous fungi.
, Funct Integr Genomics, Vol: 3, Pages: 160-170, ISSN: 1438-793XWe describe a method for gene function discovery and chemical mode-of-action analysis via nutrient utilization using a high throughput Nutritional Profiling platform suitable for filamentous microorganisms. We have optimized the growth conditions for each fungal species to produce reproducible optical density growth measurements in microtiter plates. We validated the Nutritional Profiling platform using a nitrogen source utilization assay to analyze 21 Aspergillus nidulans strains with mutations in the master nitrogen regulatory gene, areA. Analysis of these data accurately reproduced expected results and provided new data to demonstrate that this platform is suitable for fine level phenotyping of filamentous fungi. Next, we analyzed the differential responses of two fungal species to a glutamine synthetase inhibitor, illustrating chemical mode-of-action analysis. Finally, a comparative phenotypic study was performed to characterize carbon catabolite repression in four fungal species using a carbon source utilization assay. The results demonstrate differentiation between two Aspergillus species and two diverse plant pathogens and provide a wealth of new data on fungal nutrient utilization. Thus, these assays can be used for gene function and chemical mode-of-action analysis at the whole organism level as well as interspecies comparisons in a variety of filamentous fungi. Additionally, because uniform distribution of growth within wells is maintained, comparisons between yeast and filamentous forms of a single organism can be performed.
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Journal articleCopley SJ, Wells AU, Sivakumaran P, et al., 2003,
Asbestosis and idiopathic pulmonary fibrosis: Comparison of thin-section CT features
, RADIOLOGY, Vol: 229, Pages: 731-736, ISSN: 0033-8419- Author Web Link
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- Citations: 76
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Journal articleAllen M, Heinzmann A, Noguchi E, et al., 2003,
Positional cloning of a novel gene influencing asthma from Chromosome 2q14
, NATURE GENETICS, Vol: 35, Pages: 258-263, ISSN: 1061-4036- Author Web Link
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- Citations: 247
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Journal articleRanganathan SC, Goetz I, Hoo AF, et al., 2003,
Assessment of tidal breathing parameters in infants with cystic fibrosis
, EUROPEAN RESPIRATORY JOURNAL, Vol: 22, Pages: 761-766, ISSN: 0903-1936- Author Web Link
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- Citations: 28
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Journal articleJohnson H, Whiteford JR, Eckert SE, et al., 2003,
Production and secretion of <i>Aspergillus nidulans</i> catalase B in filamentous fungi driven by the promoter and signal peptide of the <i>Cladosporium fulvum</i> hydrophobin gene <i>hcf-1</i>
, CURRENT GENETICS, Vol: 44, Pages: 155-163, ISSN: 0172-8083- Author Web Link
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- Citations: 3
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Journal articleTraherne JA, Hill MR, D'Amato M, et al., 2003,
LD mapping of maternally and non-maternally derived alleles and atopy in <i>FcεRI-</i>β
, HUMAN MOLECULAR GENETICS, Vol: 12, Pages: 2577-2585, ISSN: 0964-6906- Author Web Link
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- Citations: 35
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