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• Journal article
  Cota E, Clarke J, 2000,

  Folding of beta-sandwich proteins: Three-state transition of a fibronectin type III module

  , PROTEIN SCIENCE, Vol: 9, Pages: 112-120, ISSN: 0961-8368
  • Author Web Link
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  • Citations: 66
• Journal article
  Bismarck A, Richter D, Wuertz C, Kumru ME, Song B, Springer Jet al., 2000,

  Adhesion: Comparison Between Physico-chemical Expected and Measured Adhesion of Oxygen-plasma-treated Carbon Fibers and Polycarbonate

  , Journal of Adhesion, Vol: 73, Pages: 19-42
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• Journal article
  Ernst M, Bismarck A, Springer J, Jekel Met al., 2000,

  Zeta-potential and rejection rates of a polyethersulfone nanofiltration membrane in single salt solutions

  , Journal of Membrane Science, Vol: 165, Pages: 251-259
  • Cite
• Journal article
  Bismarck A, Springer J, Mohantry AK, Hinrichsen G, Khan MAet al., 2000,

  Characterization of Several Modified Jute Fibers using Zeta-Potential Measurements

  , Colloid and Polymer Science, Vol: 287, Pages: 229-235
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• Journal article
  Bismarck A, Pfeifer G, Springer J, 2000,

  Study on surface- and mechanical fiber characteristics and their effect on epoxy composite properties tuned by continuous anodic carbon fiber oxidation

  , Journal of Adhesion, Vol: 14, Pages: 661-690
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• Conference paper
  Byrne B, Jormakka M, Abramson J, Iwata Set al., 2000,

  A novel, fusion protein strategy for membrane protein crystallisation.

  , Publisher: INT UNION CRYSTALLOGRAPHY, Pages: S58-S58, ISSN: 2053-2733
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• Journal article
  Ito K, J Barnes P, M Adcock I, 2000,

  Histone acetylation and deacetylation.

  , Methods Mol Med, Vol: 44, Pages: 309-319, ISSN: 1543-1894

  In the resting cell, DNA is tightly compacted to prevent transcription factor accessibility. During activation of the cell, this compact inaccessible DNA is made available to DNA-binding proteins, thus allowing the induction of gene transcription (1 ,2). DNA is packaged into chromatin, a highly organized and dynamic protein-DNA complex. The fundamental subunit of chromatin, the nucleosome, is composed of an octomer of four core histones, an H3/H4 tetramer and two H2A/H2B dimers, surrounded by 146 bp DNA (2,3). The packaging of DNA into nucleosomes acts as a barrier to the initiation of transcription by preventing the access of transcriptional factors, and RNA polymerase II, to their cognate recognition sequences (4). Specific lysine residues in the N-terminal tails of the core histone can be post-translationally modified by acetylation of the ε-amino group. The dynamic equilibrium of core histone acetylation is established and maintained by histone acetyltransferase (HAT) and histone deacetylase (HDAC). Several transcriptional regulators possess intrinsic HAT and HDAC activities, strongly suggesting that histone acetylation and deacetylation play a causal role in regulating transcription (5-8). There is compelling evidence that increased gene transcription is associated with an increase in histone acetylation; hypoacetylation of histone is correlated with reduced transcription or gene silencing (2 ,7,8; Fig 1).

  • Abstract
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• Journal article
  Habel WR, Bismarck A, 2000,

  Optimization of the adhesion of fiber optic strain sensors embedded in cement matrices: a study into long-term fiber strength

  , Journal of Structural Control, Vol: 7, Pages: 51-76
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• Journal article
  Moffatt MF, Cookson WO, 1999,

  Genetics of asthma and inflammation: the status.

  , Curr Opin Immunol, Vol: 11, Pages: 606-609, ISSN: 0952-7915

  Genome-wide screens are consistently finding linkage between asthma-associated traits and specific chromosomal loci. Several loci coincide with linkages to other inflammatory diseases, suggesting the presence of common pathways in their pathogenesis. Candidate-gene studies have found an association between a CD14 polymorphism and IgE levels, suggesting a mechanism for the increased prevalence of allergic disease. A polymorphism in Fc epsilon RI-beta shows parent-of-origin effects when associated with severe infantile eczema, further illustrating the complexity of gene-environment effects on the developing immune system.

  • Abstract
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• Journal article
  Byrne B, McGregor A, Taylor PL, Sellar R, Rodger FE, Fraser HM, Eidne KAet al., 1999,

  Isolation and characterisation of the marmoset gonadotrophin releasing hormone receptor:: Ser<SUP>140</SUP> of the DRS motif is substituted by Phe

  , JOURNAL OF ENDOCRINOLOGY, Vol: 163, Pages: 447-456, ISSN: 0022-0795
  • Author Web Link
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  • Citations: 22

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