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Conference paperGrigoryeva O, Slisenko O, Bismarck A, et al., 2007,
Effect of specific interactions on structure-property relationships of thermoplastic IPNs based on polyurethane and styrene-<i>co</i>-acrylic acid ionomers
, 3rd International Symposium on Reactive Polymers in Inhomogeneous Systems, in Melts and at Interfaces, Publisher: WILEY-V C H VERLAG GMBH, Pages: 233-239, ISSN: 1022-1360- Author Web Link
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- Citations: 8
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Journal articleHeng JYY, Pearse DF, Thielmann F, et al., 2007,
Methods to determine surface energies of natural fibres: A review
, Composite Interfaces, Vol: 14, Pages: 581-604 -
Journal articleBismarck A, Hofmeler M, Doerner G, 2007,
Effect of hot water immersion on the performance of carbon reinforced unidirectional poly(ether ether ketone) (PEEK) composites:: Stress rupture under end-loaded bending
, COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, Vol: 38, Pages: 407-426, ISSN: 1359-835X- Author Web Link
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- Citations: 36
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Journal articleAndres-Enguix I, Caley A, Yustos R, et al., 2007,
Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channelfrom Lymnaea stagnalis
, Journal of Biological Chemistry, Vol: 282, Pages: 20977-20990, ISSN: 0021-9258 -
Journal articleFisher MC, 2007,
Attila Lorincz: Nucleic acid testing for human disease, 2006
, Human Genetics, Vol: 122, Pages: 115-116, ISSN: 1432-1203 -
Journal articleBaltazar-Y-Jimenez A, Bismarck A, 2007,
Surface modification of lignocellulosic fibres in atmospheric air pressure plasma
, GREEN CHEMISTRY, Vol: 9, Pages: 1057-1066, ISSN: 1463-9262- Author Web Link
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- Citations: 43
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Book chapterBismarck A, Springer J, 2007,
Grundlagen der Kunststoff-Metallhaftung
, Handbuch Kunststoff-Metallisierung, Editors: Suchentrunk, Bad Saulgau/Württ., Publisher: Eugen G. Leuze Verlag, Pages: 24-45 -
Conference paperByrne B, 2007,
Expression, purification, and crystallisation of membrane proteins
, Conference of the NATO Advanced Study Institute on Evolving Methods for Macromolecular Cystallography, Publisher: SPRINGER, Pages: 11-23 -
Journal articleSchrettl M, Bignell E, Kragl C, et al., 2007,
Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection
, PLoS Pathogens, Vol: 3Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for virulence, but non-existent in humans, presenting a rare opportunity to strategize therapeutically against this pathogen. We have previously demonstrated that A. fumigatus excretes fusarinine C and triacetylfusarinine C to capture extracellular iron, and uses ferricrocin for hyphal iron storage. Here, we delineate pathways of intra- and extracellular siderophore biosynthesis and show that A. fumigatus synthesizes a developmentally regulated fourth siderophore, termed hydroxyferricrocin, employed for conidial iron storage. By inactivation of the nonribosomal peptide synthetase SidC, we demonstrate that the intracellular siderophores are required for germ tube formation, asexual sporulation, resistance to oxidative stress, catalase A activity, and virulence. Restoration of the conidial hydroxyferricrocin content partially rescues the virulence of the apathogenic siderophore null mutant DeltasidA, demonstrating an important role for the conidial siderophore during initiation of infection. Abrogation of extracellular siderophore biosynthesis following inactivation of the acyl transferase SidF or the nonribosomal peptide synthetase SidD leads to complete dependence upon reductive iron assimilation for growth under iron-limiting conditions, partial sensitivity to oxidative stress, and significantly reduced virulence, despite normal germ tube formation. Our findings reveal distinct cellular and disease-related roles for intra- and extracellular siderophores during mammalian Aspergillus infection.
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Journal articleMenner A, Ikem V, Salgueiro M, et al., 2007,
High internal phase emulsion templates solely stabilised by functionalised titania nanoparticles
, CHEMICAL COMMUNICATIONS, Pages: 4274-4276, ISSN: 1359-7345- Author Web Link
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- Citations: 226
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