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  • Journal article
    Heng JYY, Bismarck A, Lee AF, Wilson K, Williams DRet al., 2006,

    Anisotropic surface energetics and Wettability of macroscopic form I paracetamol crystals

    , LANGMUIR, Vol: 22, Pages: 2760-2769, ISSN: 0743-7463
  • Journal article
    Adcock IM, Chung KF, Caramori G, Ito Ket al., 2006,

    Kinase inhibitors and airway inflammation (Retracted article. See vol. 683, pg. 340, 2012)

    , EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 533, Pages: 118-132, ISSN: 0014-2999
  • Journal article
    Weinmayr G, Rzehak P, Büchele G, Björkstén B, Brunekreef B, Cookson WOC, Von Mutius E, Strachan DP, Weiland SKet al., 2006,

    International variation in prevalence of asthma symptoms and atopic sensitization: Results from phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II)

    , Allergo Journal, Vol: 15, Pages: 124-125, ISSN: 0941-8849

    Background: Atopy is generally considered to be an important risk factor for asthma. However, a literature analysis by Pearce et al. suggests that the role of atopy might have been overestimated in the past. The role of atopy in a wide range of study centers participating in ISAAC II was investigated. Methods: ISAAC II is a multicenter cross-sectional study investigating random samples of approximately 1,000 children per study center aged nine to eleven years according to the same standardized protocol. 29 study centers in 20 countries participated. Parents answered a detailed questionnaire on respiratory and atopic symptoms. In addition, skin prick tests were performed using six common inhalant allergens (Dermatophagoides pteronyssinus, Dermatophagoides farinae, cat, Alternaria tenuis, mixed tree pollen, mixed grass pollen). A skin prick test was defined positive, if the reaction to at least one allergen was ≥ 3 mm. Results: There was a large variation in the prevalence of wheeze in the past year ranging from < 1% in rural Ecuador and 3.3% in China to 22.2% in New Zealand and 26.3% in Brasil (Fig. 1). The prevalence of atopic wheeze, defined as wheeze plus a positive skin prick test, varied also largely between 0.1% in Ecuador and 13.4% in New Zealand, as did the prevalence of nonatopic wheeze from 0.5% in China to 20.9% in Brasil. The proportion of atopics varied strongly between centers and tended to be lower in low-income countries. Conclusion: The observed international pattern of asthma prevalence rates confirms findings of ISAAC phase I. Prevalence rates of wheeze were generally higher in high-income countries where they also tended to be more closely related to atopy. Further analyses of this relation are currently ongoing.

  • Journal article
    Morar N, Bowcock AM, Harper JI, Cookson WOCM, Moffatt MFet al., 2006,

    Investigation of the chromosome 17q25 <i>PSORS2</i> locus in atopic dermatitis

    , JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol: 126, Pages: 603-606, ISSN: 0022-202X
  • Journal article
    Ito K, Chung KF, Adcock IM, 2006,

    Update on glucocorticoid action and resistance

    , JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 117, Pages: 522-543, ISSN: 0091-6749
  • Journal article
    Varani K, Caramori G, Vincenzi F, Adcock I, Casolari P, Leung E, MacLennan S, Gessi S, Morello S, Barnes PJ, Ito K, Chung KF, Cavallesco G, Azzena G, Papi A, Borea PAet al., 2006,

    Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease

    , AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 173, Pages: 398-406, ISSN: 1073-449X
  • Journal article
    Solberg LC, Valdar W, Gauguier D, Nunez G, Taylor A, Arboledas-Hita C, Hernandez-Pliego P, Davidson S, Burns P, Bhattacharya S, Hough T, Higgs D, Klenerman P, Cookson WO, Zhang Y, Deacon RM, Rawlinset al., 2006,

    A Protocol for high throughput phenotyping, suitable for quantitative traits analysis in mice. Mammalian Genome 17: 129-146.

    , Mammalian Genome, ISSN: 0938-8990
  • Journal article
    Adcock IM, Ford P, Ito K, Barnes PJet al., 2006,

    Epigenetics and airways disease

    , Respiratory Research, Vol: 7, ISSN: 1465-993X
  • Journal article
    Aziz ZA, Wells AU, Bateman ED, Copley SJ, Desai SR, Grutters JC, Milne DG, Phillips GD, Smallwood D, Wiggins J, Wilsher ML, Hansell DMet al., 2006,

    Interstitial lung disease: Effects of thin-section CT on clinical decision making

    , RADIOLOGY, Vol: 238, Pages: 725-733, ISSN: 0033-8419
  • Journal article
    Solberg LC, Valdar W, Gauguier D, Nunez G, Taylor A, Burnett S, Arboledas-Hita C, Hernandez-Pliego P, Davidson S, Burns P, Bhattacharya S, Hough T, Higgs D, Klenerman P, Cookson WO, Zhang YM, Deacon RM, Rawlins JNP, Mott R, Flint Jet al., 2006,

    A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice

    , MAMMALIAN GENOME, Vol: 17, Pages: 129-146, ISSN: 0938-8990

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