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  • Journal article
    Musk AW, de Klerk NH, Cookson WO, Morgan WKet al., 1988,

    Radiographic abnormalities and duration of employment in Western Australian iron-ore miners.

    , Med J Aust, Vol: 148, Pages: 332-334, ISSN: 0025-729X

    Plain chest radiographs of 788 Pilbara iron-ore miners from Western Australia have been examined by two independent observers for evidence of pneumoconiosis. The prevalence of any radiographic abnormality (a profusion grade of 0/1 or greater on the International Labour Office [ILO] scale) was 6.7% for Reader 1 and 9.9% for Reader 2. The prevalence of a definite radiographic abnormality (a profusion grade of 1/0 or greater on the ILO scale) was 1.9% for Reader 1 and 2.8% for Reader 2. The prevalence of any abnormality, as identified by either or by both observers, was significantly related to age. The relationship between a radiographic abnormality and the duration of employment was less clear. The results indicate a need for more detailed and comprehensive studies of the effects of iron-ore dust in this industry.
  • Journal article
    SHAFFER PM, ARST HN, ESTBERG L, FERNANDO L, LY T, SITTER Met al., 1988,

    AN ASPARAGINASE OF ASPERGILLUS-NIDULANS IS SUBJECT TO OXYGEN REPRESSION IN ADDITION TO NITROGEN METABOLITE REPRESSION

    , FASEB JOURNAL, Vol: 2, Pages: A1783-A1783, ISSN: 0892-6638
  • Journal article
    Sibbald B, 1988,

    Dominant inheritance of atopic immunoglobulin-E responsiveness.

    , Lancet, Vol: 1, ISSN: 0140-6736
  • Journal article
    Cookson WO, Hopkin JM, 1988,

    Dominant inheritance of atopic immunoglobulin-E responsiveness.

    , Lancet, Vol: 1, Pages: 86-88, ISSN: 0140-6736

    The familial occurrence of atopy, defined by skin prick test responses and serum immunoglobulin-E (IgE) titres to common inhaled allergens, was studied in 239 members of 40 nuclear and 3 extended families. 90% of the atopic children in the nuclear families had at least one demonstrably atopic parent. In each extended family, atopy was vertically transmitted, and 31 of 47 (66%) offspring of marriages between atopic and unaffected parents were atopic. Of the designated atopic subjects, 83% admitted to symptoms suggesting atopic disease but only 30% regarded themselves as having any such disorder. It is suggested that atopy, the propensity to produce IgE in response to common, usually inhaled, allergens, is inherited as an autosomal dominant character but that its clinical expression depends on interaction with other factors.
  • Journal article
    Higgins RM, Cookson WO, Lane DJ, John SM, McCarthy GL, McCarthy STet al., 1987,

    Cardiac arrhythmias caused by nebulised beta-agonist therapy.

    , Lancet, Vol: 2, Pages: 863-864, ISSN: 0140-6736
  • Journal article
    Cookson WO, 1987,

    Bronchodilator action of the anti-histaminic terfenadine.

    , Br J Clin Pharmacol, Vol: 24, Pages: 120-121, ISSN: 0306-5251
  • Journal article
    ARST HN, 1987,

    FIXING ON AN ENIGMA

    , MICROBIOLOGICAL SCIENCES, Vol: 4, Pages: 58-58, ISSN: 0265-1351
  • Journal article
    Arst HN, 1987,

    Fixing on an enigma.

    , Microbiol Sci, Vol: 4, ISSN: 0265-1351
  • Journal article
    Kingsbury AC, Frost F, Cookson WO, 1987,

    Dysgerminoma, gonadoblastoma, and testicular germ cell neoplasia in phenotypically female and male siblings with 46 XY genotype.

    , Cancer, Vol: 59, Pages: 288-291, ISSN: 0008-543X

    46 XY gonadal dysgenesis is a syndrome characterized by a female phenotype with streak gonads and complicated by the frequent occurrence of germ cell tumors. The syndrome and the risk of malignant disease occur in female siblings sharing the XY genotype, and screening of female siblings and prophylactic gonadectomy in those affected is generally recommended. A family of four siblings is described in which two phenotypically female XY children and one male each have developed germ cell tumors, demonstrating that brothers of affected sisters may also be at risk.
  • Journal article
    Higgins RM, Cookson WOCM, Lane DJ, John SM, McCarthy GL, McCarthy STet al., 1987,

    Cardiac arrhythmias caused by nebulised beta-agonist therapy

    , Lancet, Vol: 2, ISSN: 0140-6736

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