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  • Journal article
    Durham SR, Craddock CF, Cookson WO, Benson MKet al., 1988,

    Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses.

    , J Allergy Clin Immunol, Vol: 82, Pages: 764-770, ISSN: 0091-6749

    Changes in airway responsiveness to histamine after allergen inhalation challenge were studied in 14 nonsmoking atopic adult subjects with asthma. Inhalation challenges with allergen and with phosphate-buffered saline (control challenge) were performed single blind in random order, with an interval of 14 days. The development of a late asthmatic response was accompanied by an increase in airway histamine responsiveness that was significant when it was compared with the airway histamine responsiveness after the control challenge at 3 hours (p less than 0.01), 24 hours (p less than 0.01), and 48 hours (p less than 0.02), with recovery at 2 weeks after allergen inhalation. The 3-hour changes in airway responsiveness occurred independently of changes in airway caliber and correlated with the magnitude of the subsequent late response (r = 0.86; p less than 0.001). These results suggest that the tissue events (possibly airway inflammation) that underlie the late asthmatic response may occur before this response becomes clinically apparent.
  • Journal article
    CERVONE F, CASTORIA R, SPANU P, BONFANTEFASOLO Pet al., 1988,

    PECTINOLYTIC ACTIVITY IN SOME ERICOID MYCORRHIZAL FUNGI

    , TRANSACTIONS OF THE BRITISH MYCOLOGICAL SOCIETY, Vol: 91, Pages: 537-539, ISSN: 0007-1536
  • Journal article
    ARST HN, 1988,

    LOCALIZATION OF SEVERAL CHROMOSOME-I GENES OF ASPERGILLUS-NIDULANS - IMPLICATIONS FOR MITOTIC RECOMBINATION

    , MOLECULAR AND GENERAL GENETICS, Vol: 213, Pages: 545-547, ISSN: 0026-8925
  • Journal article
    SHAFFER PM, ARST HN, ESTBERG L, FERNANDO L, LY T, SITTER Met al., 1988,

    AN ASPARAGINASE OF ASPERGILLUS-NIDULANS IS SUBJECT TO OXYGEN REPRESSION IN ADDITION TO NITROGEN METABOLITE REPRESSION

    , MOLECULAR AND GENERAL GENETICS, Vol: 212, Pages: 337-341, ISSN: 0026-8925
    • Cite
    • Citations: 28
  • Journal article
    SPANU P, BONFANTEFASOLO P, 1988,

    CELL-WALL-BOUND PEROXIDASE-ACTIVITY IN ROOTS OF MYCORRHIZAL ALLIUM-PORRUM

    , NEW PHYTOLOGIST, Vol: 109, Pages: 119-124, ISSN: 0028-646X
  • Journal article
    Musk AW, de Klerk NH, Cookson WO, Morgan WKet al., 1988,

    Radiographic abnormalities and duration of employment in Western Australian iron-ore miners.

    , Med J Aust, Vol: 148, Pages: 332-334, ISSN: 0025-729X

    Plain chest radiographs of 788 Pilbara iron-ore miners from Western Australia have been examined by two independent observers for evidence of pneumoconiosis. The prevalence of any radiographic abnormality (a profusion grade of 0/1 or greater on the International Labour Office [ILO] scale) was 6.7% for Reader 1 and 9.9% for Reader 2. The prevalence of a definite radiographic abnormality (a profusion grade of 1/0 or greater on the ILO scale) was 1.9% for Reader 1 and 2.8% for Reader 2. The prevalence of any abnormality, as identified by either or by both observers, was significantly related to age. The relationship between a radiographic abnormality and the duration of employment was less clear. The results indicate a need for more detailed and comprehensive studies of the effects of iron-ore dust in this industry.
  • Journal article
    SHAFFER PM, ARST HN, ESTBERG L, FERNANDO L, LY T, SITTER Met al., 1988,

    AN ASPARAGINASE OF ASPERGILLUS-NIDULANS IS SUBJECT TO OXYGEN REPRESSION IN ADDITION TO NITROGEN METABOLITE REPRESSION

    , FASEB JOURNAL, Vol: 2, Pages: A1783-A1783, ISSN: 0892-6638
  • Journal article
    Sibbald B, 1988,

    Dominant inheritance of atopic immunoglobulin-E responsiveness.

    , Lancet, Vol: 1, ISSN: 0140-6736
  • Journal article
    Cookson WO, Hopkin JM, 1988,

    Dominant inheritance of atopic immunoglobulin-E responsiveness.

    , Lancet, Vol: 1, Pages: 86-88, ISSN: 0140-6736

    The familial occurrence of atopy, defined by skin prick test responses and serum immunoglobulin-E (IgE) titres to common inhaled allergens, was studied in 239 members of 40 nuclear and 3 extended families. 90% of the atopic children in the nuclear families had at least one demonstrably atopic parent. In each extended family, atopy was vertically transmitted, and 31 of 47 (66%) offspring of marriages between atopic and unaffected parents were atopic. Of the designated atopic subjects, 83% admitted to symptoms suggesting atopic disease but only 30% regarded themselves as having any such disorder. It is suggested that atopy, the propensity to produce IgE in response to common, usually inhaled, allergens, is inherited as an autosomal dominant character but that its clinical expression depends on interaction with other factors.
  • Journal article
    Higgins RM, Cookson WO, Lane DJ, John SM, McCarthy GL, McCarthy STet al., 1987,

    Cardiac arrhythmias caused by nebulised beta-agonist therapy.

    , Lancet, Vol: 2, Pages: 863-864, ISSN: 0140-6736

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