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  • Journal article
    HULL EP, GREEN PM, ARST HN, SCAZZOCCHIO Cet al., 1989,

    CLONING AND PHYSICAL CHARACTERIZATION OF THE L-PROLINE CATABOLISM GENE-CLUSTER OF ASPERGILLUS-NIDULANS

    , MOLECULAR MICROBIOLOGY, Vol: 3, Pages: 553-559, ISSN: 0950-382X
  • Journal article
    Cookson WO, Craddock CF, Benson MK, Durham SRet al., 1989,

    Falls in peripheral eosinophil counts parallel the late asthmatic response.

    , Am Rev Respir Dis, Vol: 139, Pages: 458-462, ISSN: 0003-0805

    Peripheral eosinophil counts were measured at intervals before and after control and allergen inhalation in 14 asthmatic subjects. A relative fall in eosinophil counts was noted 9 h after allergen challenge, in contrast to the diurnal increase seen on the control day (p = 0.005). This fall in eosinophil count correlated strongly with the magnitude of the late asthmatic response (r = -0.72, p = 0.003) and with the changes in bronchial responsiveness to histamine at 3 and 24 h after allergen was given (r = 0.54, p = 0.044 and r = 0.82, p less than 0.001, respectively). The findings demonstrate eosinophil kinetics are related to the occurrence of late-phase reactions and to the associated worsening of bronchial hyperreactivity.

  • Journal article
    De Klerk NH, Cookson WOC, Musk AW, Armstrong BK, Clancy JJet al., 1989,

    Natural history of pleural thickening after exposure to crocidolite

    , undefined

    The effect of exposure to crocidolite asbestos on pleural thickening is investigated.

  • Journal article
    ARST HN, TOLLERVEY D, CADDICK MX, 1989,

    A TRANSLOCATION ASSOCIATED, LOSS-OF-FUNCTION MUTATION IN THE NITROGEN METABOLITE REPRESSION REGULATORY GENE OF ASPERGILLUS-NIDULANS CAN REVERT INTRACISTRONICALLY

    , MOLECULAR AND GENERAL GENETICS, Vol: 215, Pages: 364-367, ISSN: 0026-8925
  • Conference paper
    SPANU P, BOLLER T, 1989,

    ETHYLENE BIOSYNTHESIS IN TOMATO INFECTED BY PHYTOPHTHORA-INFESTANS

    , CONF ON BIOCHEMICAL AND PHYSIOLOGICAL ASPECTS OF ETHYLENE PRODUCTION IN LOWER AND HIGHER PLANTS, Publisher: KLUWER ACADEMIC PUBL, Pages: 255-260
  • Book chapter
    Scazzocchio C, Arst HN, 1989,

    Regulation of nitrate assimilation in Aspergillus nidulans

    , Molecular and genetic aspects of nitrate assimilation, Editors: Wray, Kinghorn, Oxford, Publisher: Oxford University Press, Pages: 299-313
  • Journal article
    MACRAE WD, BUXTON FP, SIBLEY S, GARVEN S, GWYNNE DI, DAVIES RW, ARST HNet al., 1988,

    A PHOSPHATE-REPRESSIBLE ACID-PHOSPHATASE GENE FROM ASPERGILLUS-NIGER - ITS CLONING, SEQUENCING AND TRANSCRIPTIONAL ANALYSIS

    , GENE, Vol: 71, Pages: 339-348, ISSN: 0378-1119
  • Journal article
    Durham SR, Craddock CF, Cookson WO, Benson MKet al., 1988,

    Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses.

    , J Allergy Clin Immunol, Vol: 82, Pages: 764-770, ISSN: 0091-6749

    Changes in airway responsiveness to histamine after allergen inhalation challenge were studied in 14 nonsmoking atopic adult subjects with asthma. Inhalation challenges with allergen and with phosphate-buffered saline (control challenge) were performed single blind in random order, with an interval of 14 days. The development of a late asthmatic response was accompanied by an increase in airway histamine responsiveness that was significant when it was compared with the airway histamine responsiveness after the control challenge at 3 hours (p less than 0.01), 24 hours (p less than 0.01), and 48 hours (p less than 0.02), with recovery at 2 weeks after allergen inhalation. The 3-hour changes in airway responsiveness occurred independently of changes in airway caliber and correlated with the magnitude of the subsequent late response (r = 0.86; p less than 0.001). These results suggest that the tissue events (possibly airway inflammation) that underlie the late asthmatic response may occur before this response becomes clinically apparent.

  • Journal article
    CERVONE F, CASTORIA R, SPANU P, BONFANTEFASOLO Pet al., 1988,

    PECTINOLYTIC ACTIVITY IN SOME ERICOID MYCORRHIZAL FUNGI

    , TRANSACTIONS OF THE BRITISH MYCOLOGICAL SOCIETY, Vol: 91, Pages: 537-539, ISSN: 0007-1536
  • Journal article
    ARST HN, 1988,

    LOCALIZATION OF SEVERAL CHROMOSOME-I GENES OF ASPERGILLUS-NIDULANS - IMPLICATIONS FOR MITOTIC RECOMBINATION

    , MOLECULAR AND GENERAL GENETICS, Vol: 213, Pages: 545-547, ISSN: 0026-8925

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