@article{COOKSON:1986:10.1111/j.1365-2222.1986.tb01977.x,
author = {COOKSON, WOCM and MUSK, AW and RYAN, G},
doi = {10.1111/j.1365-2222.1986.tb01977.x},
journal = {Clinical & Experimental Allergy},
pages = {425--432},
title = {Associations between asthma history, atopy, and nonspecific bronchial responsiveness in young adults},
url = {http://dx.doi.org/10.1111/j.1365-2222.1986.tb01977.x},
volume = {16},
year = {1986}
}

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TY  - JOUR
AB  - In 105 subjects taken from a student population and aged between 15 and 30 there was a strong positive association between the presence of the atopic state, defined by skin tests, and a high level of nonspecific bronchial responsiveness to methacholine (χ2= 10·5, d.f. = 2, P= 0·01). Regression analysis showed a history of asthma, and the symptom of wheeze, to be predominantly predicted by the degree of bronchial responsiveness (R2= 31%), with only a minor independent contribution from the degree of atopy (R2 a furthur 5%). The genetic or other reasons for the association between bronchial responsiveness and atopy may have importance in understanding the aetiology of allergic asthma. Copyright © 1986, Wiley Blackwell. All rights reserved
AU  - COOKSON,WOCM
AU  - MUSK,AW
AU  - RYAN,G
DO  - 10.1111/j.1365-2222.1986.tb01977.x
EP  - 432
PY  - 1986///
SN  - 0954-7894
SP  - 425
TI  - Associations between asthma history, atopy, and nonspecific bronchial responsiveness in young adults
T2  - Clinical & Experimental Allergy
UR  - http://dx.doi.org/10.1111/j.1365-2222.1986.tb01977.x
VL  - 16
ER  - 

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