BibTex format
@article{Young:1994:10.1111/j.1365-2222.1994.tb00931.x,
author = {Young, RP and Dekker, JW and Wordsworth, BP and Schou, C and Pile, KD and Matthiesen, F and Rosenberg, WM and Bell, JI and Hopkin, JM and Cookson, WO},
doi = {10.1111/j.1365-2222.1994.tb00931.x},
journal = {Clin Exp Allergy},
pages = {431--439},
title = {HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens.},
url = {http://dx.doi.org/10.1111/j.1365-2222.1994.tb00931.x},
volume = {24},
year = {1994}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - In order to test for human histocompatibility leucocyte antigens (HLA) class II restriction of IgE responses, 431 subjects from 83 families were genotyped at the HLA-DR and HLA-DP loci and serotyped for IgE responses to six major allergens from common aero-allergen sources. A possible excess of HLA-DR1 was found in subjects who were responsive to Fel d I compared with those who were not (Odds Ratio (OR) = 2, P = 0.002), and a possible excess of HLA-DR4 was found in subjects responsive to Alt a I (OR = 1.9, P = 0.006). Increased sharing of HLA-DR/DP haplotypes was seen in sibling pairs responding to both allergens. Der p I, Der p II, Phl p V and Can f I were not associated with any definite excess of HLA-DR alleles. No significant correlations were seen with HLA-DP genotype and reactivity to any of the allergens. The results suggest class II HLA restriction is insufficient to account for individual differences in reactivity to common allergens.
AU - Young,RP
AU - Dekker,JW
AU - Wordsworth,BP
AU - Schou,C
AU - Pile,KD
AU - Matthiesen,F
AU - Rosenberg,WM
AU - Bell,JI
AU - Hopkin,JM
AU - Cookson,WO
DO - 10.1111/j.1365-2222.1994.tb00931.x
EP - 439
PY - 1994///
SN - 0954-7894
SP - 431
TI - HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens.
T2 - Clin Exp Allergy
UR - http://dx.doi.org/10.1111/j.1365-2222.1994.tb00931.x
UR - https://www.ncbi.nlm.nih.gov/pubmed/8087654
VL - 24
ER -