In this section
@article{Moffatt:1999:10.1016/s0952-7915(99)00024-2,
author = {Moffatt, MF and Cookson, WO},
doi = {10.1016/s0952-7915(99)00024-2},
journal = {Curr Opin Immunol},
pages = {606--609},
title = {Genetics of asthma and inflammation: the status.},
url = {http://dx.doi.org/10.1016/s0952-7915(99)00024-2},
volume = {11},
year = {1999}
}
TY - JOUR
AB - Genome-wide screens are consistently finding linkage between asthma-associated traits and specific chromosomal loci. Several loci coincide with linkages to other inflammatory diseases, suggesting the presence of common pathways in their pathogenesis. Candidate-gene studies have found an association between a CD14 polymorphism and IgE levels, suggesting a mechanism for the increased prevalence of allergic disease. A polymorphism in Fc epsilon RI-beta shows parent-of-origin effects when associated with severe infantile eczema, further illustrating the complexity of gene-environment effects on the developing immune system.
AU - Moffatt,MF
AU - Cookson,WO
DO - 10.1016/s0952-7915(99)00024-2
EP - 609
PY - 1999///
SN - 0952-7915
SP - 606
TI - Genetics of asthma and inflammation: the status.
T2 - Curr Opin Immunol
UR - http://dx.doi.org/10.1016/s0952-7915(99)00024-2
UR - https://www.ncbi.nlm.nih.gov/pubmed/10631542
VL - 11
ER -
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