@article{Moffatt:1992:10.1111/j.1365-2222.1992.tb00128.x,
author = {Moffatt, MF and Sharp, PA and Faux, JA and Young, RP and Cookson, WO and Hopkin, JM},
doi = {10.1111/j.1365-2222.1992.tb00128.x},
journal = {Clin Exp Allergy},
pages = {1046--1051},
title = {Factors confounding genetic linkage between atopy and chromosome 11q.},
url = {http://dx.doi.org/10.1111/j.1365-2222.1992.tb00128.x},
volume = {22},
year = {1992}
}

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TY  - JOUR
AB  - The results of testing for linkage between atopy and the chromosome 11 marker D11S97 is shown for all the 723 subjects genotyped by us up to January 1992. Lod score estimations were confounded by the high population prevalence of atopy, maternal inheritance of atopy at the 11q locus, genetic heterogeneity, and excess of atopy in families not ascertained through a single proband. Affected sib-pair analysis shows evidence for linkage which is not dependent on the definition of atopy or model specification. We suggest that presentation of sib-pair data will be suitable for meta-analysis of the different studies of genetic linkage and atopy.
AU  - Moffatt,MF
AU  - Sharp,PA
AU  - Faux,JA
AU  - Young,RP
AU  - Cookson,WO
AU  - Hopkin,JM
DO  - 10.1111/j.1365-2222.1992.tb00128.x
EP  - 1051
PY  - 1992///
SN  - 0954-7894
SP  - 1046
TI  - Factors confounding genetic linkage between atopy and chromosome 11q.
T2  - Clin Exp Allergy
UR  - http://dx.doi.org/10.1111/j.1365-2222.1992.tb00128.x
UR  - https://www.ncbi.nlm.nih.gov/pubmed/1486532
VL  - 22
ER  - 

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