A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.
Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.
@article{Vyas:2018:10.1364/BOE.9.004649,
author = {Vyas, K and Hughes, M and Gil, Rosa B and Yang, GZ},
doi = {10.1364/BOE.9.004649},
journal = {Biomedical Optics Express},
pages = {4649--4664},
title = {Fiber bundle shifting endomicroscopy for high resolution imaging},
url = {http://dx.doi.org/10.1364/BOE.9.004649},
volume = {9},
year = {2018}
}
TY - JOUR
AB - Flexible endomicroscopes commonly use coherent fiber bundles with high core densities to facilitate high-resolution in vivo imaging during endoscopic and minimally-invasive procedures. However, under-sampling due to the inter-core spacing limits the spatial resolution, making it difficult to resolve smaller cellular features. Here, we report a compact and rapid piezoelectric transducer (PZT) based bundle-shifting endomicroscopy system in which a super-resolution (SR) image is restored from multiple pixelation-limited images by computational means. A miniaturized PZT tube actuates the fiber bundle behind a GRIN micro-lens and a Delaunay triangulation based algorithm reconstructs an enhanced SR image. To enable real-time cellular-level imaging, imaging is performed using a line-scan confocal laser endomicroscope system with a raw frame rate of 120 fps, delivering up to 2 times spatial resolution improvement for a field of view of 350 µm at a net frame rate of 30 fps. The resolution enhancement is confirmed using resolution phantoms and ex vivo fluorescence endomicroscopy imaging of human breast specimens is demonstrated.
AU - Vyas,K
AU - Hughes,M
AU - Gil,Rosa B
AU - Yang,GZ
DO - 10.1364/BOE.9.004649
EP - 4664
PY - 2018///
SN - 2156-7085
SP - 4649
TI - Fiber bundle shifting endomicroscopy for high resolution imaging
T2 - Biomedical Optics Express
UR - http://dx.doi.org/10.1364/BOE.9.004649
UR - http://hdl.handle.net/10044/1/62703
VL - 9
ER -