A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.


BibTex format

author = {Berthelot, M and Henry, FP and Hunter, J and Leff, D and Wood, S and Jallali, N and Dex, E and Ladislava, L and Lo, B and Yang, GZ},
doi = {10.1117/1.JBO.24.6.067001},
journal = {Journal of Biomedical Optics},
pages = {067001--1--067001--8},
title = {Pervasive wearable device for free tissue transfer monitoring based on advanced data analysis: clinical study report},
url = {http://dx.doi.org/10.1117/1.JBO.24.6.067001},
volume = {24},
year = {2019}

RIS format (EndNote, RefMan)

AB - Free tissue transfer (FTT) surgery for breast reconstruction following mastectomy has become a routineoperation with high success rates. Although failure is low, it can have a devastating impact on patient recovery,prognosis and psychological well-being. Continuous and objective monitoring of tissue oxygen saturation (StO2) hasshown to reduce failure rates through rapid detection time of postoperative vascular complications. We have developeda pervasive wearable wireless device that employs near infrared spectroscopy (NIRS) to continuously monitor FTTviaStO2measurement. Previously tested on different models, this paper introduces the results of a clinical study. Thegoal of the study is to demonstrate the developed device can reliably detectStO2variations in a clinical setting: 14patients were recruited. Advanced data analysis were performed on theStO2variations, the relativeStO2gradientchange, and, the classification of theStO2within different clusters of blood occlusion level (from 0% to 100% at 25%step) based on previous studies made on a vascular phantom and animals. The outcomes of the clinical study concurwith previous experimental results and the expected biological responses. This suggests the device is able to correctlydetect perfusion changes and provide real-time assessment on the viability of the FTT in a clinical setting.
AU - Berthelot,M
AU - Henry,FP
AU - Hunter,J
AU - Leff,D
AU - Wood,S
AU - Jallali,N
AU - Dex,E
AU - Ladislava,L
AU - Lo,B
AU - Yang,GZ
DO - 10.1117/1.JBO.24.6.067001
EP - 1
PY - 2019///
SN - 1083-3668
SP - 067001
TI - Pervasive wearable device for free tissue transfer monitoring based on advanced data analysis: clinical study report
T2 - Journal of Biomedical Optics
UR - http://dx.doi.org/10.1117/1.JBO.24.6.067001
UR - https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-24/issue-06/067001/Pervasive-wearable-device-for-free-tissue-transfer-monitoring-based-on/10.1117/1.JBO.24.6.067001.full?SSO=1
UR - http://hdl.handle.net/10044/1/70600
VL - 24
ER -