A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.


BibTex format

author = {Berthelot, M and Ashcroft, J and Boshier, P and Henry, FP and Hunter, J and Lo, B and Yang, G-Z and Leff, D},
doi = {10.1097/GOX.0000000000002437},
journal = {Plastic and Reconstructive Surgery Global Open},
pages = {1--8},
title = {Use of near infrared spectroscopy and implantable Doppler for postoperative monitoring of free tissue transfer for breast reconstruction: a systematic review and meta-analysis},
url = {http://dx.doi.org/10.1097/GOX.0000000000002437},
volume = {7},
year = {2019}

RIS format (EndNote, RefMan)

AB - Background: Failure to accurately assess the perfusion of free tissue transfer (FTT) in the early postoperative periodmay contribute to failure, which is a source of major patient morbidity and healthcare costs.Goal: This systematic review and meta-analysis aims to evaluate and appraise current evidence for the use of nearinfrared spectroscopy (NIRS) and/or implantable Doppler (ID) devices compared with conventional clinicalassessment (CCA) for postoperative monitoring of FTT in reconstructive breast surgery.Methods: A systematic literature search was performed in accordance with the PRISMA guidelines. Studies in humansubjects published within the last decade relevant to the review question were identified. Meta-analysis using randomeffects models of FTT failure rate and STARD scoring were then performed on the retrieved publications.Results: 19 studies met the inclusions criteria. For NIRS and ID, the mean sensitivity for the detection of FTT failure is99.36% and 100% respectively, with average specificity of 99.36% and 97.63% respectively. From studies withsufficient reported data, meta-analysis results demonstrated that both NIRS (OR = 0.09 [0.02, 0.36], P < 0.001) and ID(OR = 0.39 [0.27, 0.95], P = 0.04) were associated with significant reduction of FTT failure rates compared to CCA.Conclusion: The use of ID and NIRS provide equivalent outcomes in detecting FTT failure and were superior to CCA.The ability to acquire continuous objective physiological data regarding tissue perfusion is a perceived advantage ofthese techniques. Reduced clinical staff workload and minimised hospital costs are also perceived as positiveconsequences of their use.
AU - Berthelot,M
AU - Ashcroft,J
AU - Boshier,P
AU - Henry,FP
AU - Hunter,J
AU - Lo,B
AU - Yang,G-Z
AU - Leff,D
DO - 10.1097/GOX.0000000000002437
EP - 8
PY - 2019///
SN - 2169-7574
SP - 1
TI - Use of near infrared spectroscopy and implantable Doppler for postoperative monitoring of free tissue transfer for breast reconstruction: a systematic review and meta-analysis
T2 - Plastic and Reconstructive Surgery Global Open
UR - http://dx.doi.org/10.1097/GOX.0000000000002437
UR - https://insights.ovid.com/crossref?an=01720096-201910000-00019
UR - http://hdl.handle.net/10044/1/71943
VL - 7
ER -