A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.


BibTex format

author = {Chen, C-M and Kwasnicki, RM and Curto, VF and Yang, G-Z and Lo, BPL},
doi = {10.1109/JSEN.2019.2917122},
journal = {IEEE Sensors Journal},
pages = {8233--8240},
title = {Tissue oxygenation sensor and an active in vitro phantom for sensor Validation},
url = {http://dx.doi.org/10.1109/JSEN.2019.2917122},
volume = {19},
year = {2019}

RIS format (EndNote, RefMan)

AB - A free flap is a tissue reconstruction procedure where healthy tissue is harvested to cover up vital structures after wound debridement. Microvascular anastomoses are carried out to join the arteries and veins of the flap with recipient vessels near the target site. Continuous monitoring is required to identify the flap failure and enable early intervention to salvage the flap. Although there are medical instruments that can assist surgeons in monitoring flap viability, high upfront costs and time-consuming data interpretation have hindered the use of such technologies in practice. Surgeons still rely largely on the clinical examination to monitor flaps after operations. This paper presents a low-cost, low-power (6.6 mW), and miniaturized Hamlyn StO 2 (tissue oxygen saturation) sensor that can be embodied as a plaster and attached to a flap for real-time monitoring. Similar to the design of oxygen saturation (SpO 2 /SaO 2 ) sensors, the Hamlyn StO 2 sensor was designed based on photoplethysmography (PPG), but with a different target of quantifying tissue perfusion rather than capturing pulsatile flow. To understand the spectral response to oxygenation/deoxygenation and vascular flow, an active in vitro silicone phantom was developed. The new sensor was validated using the silicone phantom and compared with a commercially available photospectroscopy and laser Doppler machine (O2C, LEA, Germany). In addition, in vivo experiments were conducted using a brachial pressure cuff forearm ischemia model. The experiment results have shown a high correlation between the proposed sensor and the O2C machine (r = 0.672 and p <; 0.001), demonstrating the potential value of the of the proposed low-cost sensor in post-operative free flap monitoring.
AU - Chen,C-M
AU - Kwasnicki,RM
AU - Curto,VF
AU - Yang,G-Z
DO - 10.1109/JSEN.2019.2917122
EP - 8240
PY - 2019///
SN - 1530-437X
SP - 8233
TI - Tissue oxygenation sensor and an active in vitro phantom for sensor Validation
T2 - IEEE Sensors Journal
UR - http://dx.doi.org/10.1109/JSEN.2019.2917122
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000481964500049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - https://ieeexplore.ieee.org/document/8715803
UR - http://hdl.handle.net/10044/1/75181
VL - 19
ER -