Sensing

A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.

2 column colour block - Research areas

Body Sensor Networks

Body Sensor Networks

The last decade has witnessed a rapid surge of interest in new sensing and monitoring devices for healthcare and the use of wireless wearable devices for clinical applications. One key development in this area is implantable in vivo monitoring and intervention devices.
Surgical Implants

Surgical Implants

One of the major focuses of the Hamlyn Centre is the development of miniaturised sensors embodied either as smart surgical appliances or implants to enhance the safety of surgical procedures, enhance patient care, and also the patient's quality of life.

2 column colour block - Research areas 2

ESPRIT

IoT and Smart Environments

Our main research in IoT and smart environments is focussed on the challenges of ambient sensing through the introduction of novel sensing platforms, self-configuration approaches, self-adaptive techniques, and seamless integration with wearable sensors.
Smart Environments

ESPRIT

The vision of ESPRIT is to position UK at the forefront of pervasive sensing in elite sports and promote its wider application in public life-long health, wellbeing and healthcare. Our work addresses some of the key challenges related to miniaturised wearable sensors for sports.

Citation

BibTex format

@article{Kim:2020:10.1002/adom.201901934,
author = {Kim, JA and Wales, D and Thompson, A and Yang, G-Z},
doi = {10.1002/adom.201901934},
journal = {Advanced Optical Materials},
pages = {1--12},
title = {Fiber-optic SERS probes fabricated using two-photon polymerization for rapid detection of bacteria},
url = {http://dx.doi.org/10.1002/adom.201901934},
volume = {8},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - This study presents a novel fiber-optic surface-enhanced Raman spectroscopy (SERS) probe (SERS-on-a-tip) fabricated using a simple, two-step protocol based on off-the-shelf components and materials, with a high degree of controllability and repeatability. Two-photon polymerization and subsequent metallization was adopted to fabricate a range of SERS arrays on both planar substrates and end-facets of optical fibers. For the SERS-on-a-tip probes, a limit of detection of 10-7 M (Rhodamine 6G) and analytical enhancement factors of up to 1300 were obtained by optimizing the design, geometry and alignment of the SERS arrays on the tip of the optical fiber. Furthermore, strong repeatability and consistency were achieved for the fabricated SERS arrays, demonstrating that the technique may be suitable for large-scale fabrication procedures in the future. Finally, rapid SERS detection of live Escherichia coli cells was demonstrated using integration times in the milliseconds to seconds range. This result indicates strong potential for in vivo diagnostic use, particularly for detection of infections. Moreover, to the best of our knowledge, this represents the first report of detection of live, unlabeled bacteria using a fiber-optic SERS probe.
AU  - Kim,JA
AU  - Wales,D
AU  - Thompson,A
AU  - Yang,G-Z
DO  - 10.1002/adom.201901934
EP  - 12
PY  - 2020///
SN  - 2195-1071
SP  - 1
TI  - Fiber-optic SERS probes fabricated using two-photon polymerization for rapid detection of bacteria
T2  - Advanced Optical Materials
UR  - http://dx.doi.org/10.1002/adom.201901934
UR  - https://onlinelibrary.wiley.com/doi/full/10.1002/adom.201901934
UR  - http://hdl.handle.net/10044/1/75908
VL  - 8
ER  -
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