A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.


Citation

BibTex format

@inproceedings{He:2020:10.1117/12.2545516,
author = {He, C and Chang, J and He, H and Liu, S and Elson, DS and Ma, H and Booth, MJ},
doi = {10.1117/12.2545516},
publisher = {SPIE},
title = {GRIN lens based polarization endoscope – from conception to application},
url = {http://dx.doi.org/10.1117/12.2545516},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - CPAPER
AB - Graded index (GRIN) lenses focus light through a radially symmetric refractive index profile. It is not widely appreciated that the ion-exchange process that creates the index profile also causes a radially symmetric birefringence variation. This property is usually considered a nuisance, such that manufacturing processes are optimized to keep it to a minimum. Here, a new Mueller matrix (MM) polarimeter based on a spatially engineered polarization state generating array and GRIN lens cascade for measuring the MM of a region of a sample in a single-shot is presented. We explore using the GRIN lens cascade for a functional analyzer to calculate multiple Stokes vectors and the MM of the target in a snapshot. A designed validation sample is used to test the reliability of this polarimeter. To understand more potential biomedical applications, human breast ductal carcinoma slides at two pathological progression stages are detected by this polarimeter. The MM polar decomposition parameters then can be calculated from the measured MMs, and quantitatively compared with the equivalent data sampled by a MM microscope. The results indicate that the polarimeter and the measured polarization parameters are capable of differentiating the healthy and carcinoma status of human breast tissue efficiently. It has potential to act as a polarization detected fiber-based probe to assist further minimally invasive clinical diagnosis.
AU - He,C
AU - Chang,J
AU - He,H
AU - Liu,S
AU - Elson,DS
AU - Ma,H
AU - Booth,MJ
DO - 10.1117/12.2545516
PB - SPIE
PY - 2020///
TI - GRIN lens based polarization endoscope – from conception to application
UR - http://dx.doi.org/10.1117/12.2545516
UR - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11251/2545516/GRIN-lens-based-polarization-endoscope--from-conception-to-application/10.1117/12.2545516.full?SSO=1
ER -