A primary motivation of our research is the monitoring of physical, physiological, and biochemical parameters - in any environment and without activity restriction and behaviour modification - through using miniaturised, wireless Body Sensor Networks (BSN). Key research issues that are currently being addressed include novel sensor designs, ultra-low power microprocessor and wireless platforms, energy scavenging, biocompatibility, system integration and miniaturisation, processing-on-node technologies combined with novel ASIC design, autonomic sensor networks and light-weight communication protocols. Our research is aimed at addressing the future needs of life-long health, wellbeing and healthcare, particularly those related to demographic changes associated with an ageing population and patients with chronic illnesses. This research theme is therefore closely aligned with the IGHI’s vision of providing safe, effective and accessible technologies for both developed and developing countries.

Some of our latest works were exhibited at the 2015 Royal Society Summer Science Exhibition.


Citation

BibTex format

@article{Anastasova:2016:10.1016/j.bios.2016.09.038,
author = {Anastasova, S and Crewther, B and Bembnowicz, P and Curto, V and Ip, HMD and Rosa, B and Yang, GZ},
doi = {10.1016/j.bios.2016.09.038},
journal = {Biosensors and Bioelectronics},
pages = {139--145},
title = {A Wearable Multisensing Patch for Continuous Sweat Monitoring},
url = {http://dx.doi.org/10.1016/j.bios.2016.09.038},
volume = {93},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - In sport, exercise and healthcare settings, there is a need for continuous, non-invasive monitoring of biomarkers to assess human performance, health and wellbeing. Here we report the development of a flexible microfluidic platform with fully integrated sensing for on-body testing of human sweat. The system can simultaneously and selectively measure metabolite (e.g. lactate) and electrolytes (e.g. pH, sodium) together with temperature sensing for internal calibration. The construction of the platform is designed such that continuous flow of sweat can pass through an array of flexible microneedle type of sensors (50 µm diameter) incorporated in a microfluidic channel. Potentiometric sodium ion sensors were developed using a polyvinyl chloride (PVC) functional membrane deposited on an electrochemically deposited internal layer of Poly(3,4-ethylenedioxythiophene) (PEDOT) polymer. The pH sensing layer is based on a highly sensitive membrane of iridium oxide (IrOx). The amperometric-based lactate sensor consists of doped enzymes deposited on top of a semipermeable copolymer mebrane and outer polyurethane layers. Real-time data were collected from human subjects during cycle ergometry and treadmill running. A detailed comparison of sodium, lactate and cortisol from saliva is reported, demonstrating the potential of the multi-sensing platform for tracking these outcomes. In summary, a fully integrated sensor for continuous, simultaneous and selective measurement of sweat metabolites, electrolytes and temperature was achieved using a flexible microfluidic platform. This system can also transmit information wirelessly for ease of collection and storage, with the potential for real-time data analytics.
AU - Anastasova,S
AU - Crewther,B
AU - Bembnowicz,P
AU - Curto,V
AU - Ip,HMD
AU - Rosa,B
AU - Yang,GZ
DO - 10.1016/j.bios.2016.09.038
EP - 145
PY - 2016///
SN - 0956-5663
SP - 139
TI - A Wearable Multisensing Patch for Continuous Sweat Monitoring
T2 - Biosensors and Bioelectronics
UR - http://dx.doi.org/10.1016/j.bios.2016.09.038
UR - http://hdl.handle.net/10044/1/52700
VL - 93
ER -