Centre for Molecular Immunology and Inflammation
Exploring key molecular pathways in autoimmunity, inflammation and cancer
The Centre for Molecular Immunology and Inflammation studies the key molecular pathways that drive and regulate autoimmune/inflammatory diseases and cancer. This research utilises a broad range of approaches, including genetic screens, biochemical analysis of signalling pathways, biophysical and structural analyses, ‘omics’ technologies and drug discovery. Conditional genetic models and patient investigations are used to dissect the function of the molecular pathways studied in autoimmunity and cancer. The overarching goal is to develop new therapies through increased mechanistic understanding at the molecular level.
Key research areas include haematological and solid cancers, psoriasis and inflammatory bowel disease.
Funding sources have included the Medical Research Council, Cancer Research UK, Bloodwise, British Heart Foundation, National Psoriasis Foundation, the National Institutes of Health and the NIHR Imperial BRC.
Professor Steven Ley
Personal detailsProfessor Steven Ley Co-Director, Centre for Molecular Immunology and Inflammation
Send email+44 (0)20 8816 2463
Steve Ley is Professor and Chair of Molecular Immunology. His group studies the regulation and function of key MAP kinase and NF-kB signalling pathways in inflammation and immunity.
Commonwealth Building, Hammersmith Campus
Professor Guido Franzoso
Personal detailsProfessor Guido Franzoso Co-Director, Centre for Molecular Immunology and Inflammation
Send email+44 (0)20 3313 8421
Guido Franzoso is Professor and Chair of Signal Transduction and Inflammation and holds an Honorary position at Imperial College NHS Trust. His research interest is the regulation and function of NF-κB transcription factors.
10N8, Commonwealth Building, Hammersmith Campus
Professor Danny Altmann
Danny Altmann heads a lab at the Hammersmith Hospital Campus of Imperial, with expertise in the HLA system, antigen discovery, T cell subsets and NK cells.
7S7, Hammersmith Hospital, Hammersmith Campus
Professor Victor Tybulewicz
Personal detailsProfessor Victor Tybulewicz Affiliated Principal Investigator (Francis Crick Institute)
Send email+44 (0)20 3796 1612
Professor Victor Tybulewicz is a Senior Group Leader and Associated Research Director at the Francis Crick Institute and a Professor at Imperial College. Read full details of Professor Tybulewicz's research interests .
L2-2720, Francis Crick Institute, The Francis Crick Institute