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• Journal article
  BAX B, BLABER M, FERGUSON G, STERNBERG MJE, WALLS PHet al., 1993,

  PREDICTION OF THE 3-DIMENSIONAL STRUCTURES OF THE NERVE GROWTH-FACTOR AND EPIDERMAL GROWTH-FACTOR BINDING-PROTEINS (KALLIKREINS) AND AN HYPOTHETICAL STRUCTURE OF THE HIGH-MOLECULAR-WEIGHT COMPLEX OF EPIDERMAL GROWTH-FACTOR WITH ITS BINDING-PROTEIN

  , PROTEIN SCIENCE, Vol: 2, Pages: 1229-1241, ISSN: 0961-8368
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  • Citations: 13
• Journal article
  KHOO KH, MORRIS HR, DELL A, 1993,

  FAB-MS SEQUENCING OF MYCOBACTERIAL GLYCOLIPID ANTIGENS

  , GLYCOCONJUGATE JOURNAL, Vol: 10, Pages: 335-335, ISSN: 0282-0080
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• Journal article
  REASON AJ, MORRIS HR, DELL A, 1993,

  MASS-SPECTROMETRIC ANALYSIS OF THE GLYCOSYLATION OF THE ENZYME LECITHIN-CHOLESTEROL ACYL TRANSFERASE

  , GLYCOCONJUGATE JOURNAL, Vol: 10, Pages: 279-279, ISSN: 0282-0080
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• Journal article
  MULLER HM, CRAMPTON JM, DELLATORRE A, SINDEN R, CRISANTI Aet al., 1993,

  MEMBERS OF A TRYPSIN GENE FAMILY IN ANOPHELES-GAMBIAE ARE INDUCED IN THE GUT BY BLOOD MEAL

  , EMBO JOURNAL, Vol: 12, Pages: 2891-2900, ISSN: 0261-4189
  • Author Web Link
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  • Citations: 151
• Journal article
  FRANKS NP, LIEB WR, 1993,

  SELECTIVE ACTIONS OF VOLATILE GENERAL-ANESTHETICS AT MOLECULAR AND CELLULAR-LEVELS

  , BRITISH JOURNAL OF ANAESTHESIA, Vol: 71, Pages: 65-76, ISSN: 0007-0912
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  • Citations: 217
• Journal article
  CHARALAMBOUS M, SHELLEY AJ, ARZUBE M, 1993,

  DISTRIBUTION AND TAXONOMIC STATUS OF CHROMOSOMAL FORMS OF THE ONCHOCERCIASIS VECTOR SIMULIUM-EXIGUUM IN CENTRAL ECUADOR

  , MEDICAL AND VETERINARY ENTOMOLOGY, Vol: 7, Pages: 299-303, ISSN: 0269-283X
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  • Citations: 11
• Journal article
  MULLER HM, RECKMANN I, HOLLINGDALE MR, BUJARD H, ROBSON KJH, CRISANTI Aet al., 1993,

  THROMBOSPONDIN RELATED ANONYMOUS PROTEIN (TRAP) OF PLASMODIUM-FALCIPARUM BINDS SPECIFICALLY TO SULFATED GLYCOCONJUGATES AND TO HEPG2 HEPATOMA-CELLS SUGGESTING A ROLE FOR THIS MOLECULE IN SPOROZOITE INVASION OF HEPATOCYTES

  , EMBO JOURNAL, Vol: 12, Pages: 2881-2889, ISSN: 0261-4189
  • Author Web Link
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  • Citations: 176
• Journal article
  MULLER HM, RANUCCI L, POZIO E, CRISANTI Aet al., 1993,

  A METHOD FOR COLLECTING LARGE QUANTITIES OF CRYPTOSPORIDIUM PARASITES

  , PARASITOLOGY TODAY, Vol: 9, Pages: 261-263, ISSN: 0169-4758
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  • Citations: 6
• Journal article
  Müller HM, Vizioli I, della Torre A, Crisanti Aet al., 1993,

  Temporal and spatial expression of serine protease genes in Anopheles gambiae.

  , Parassitologia, Vol: 35 Suppl, Pages: 73-76, ISSN: 0048-2951

  Serine proteases play a crucial role during the digestion of the blood meal in the mosquito gut. The isolation and the analysis of the genomic organisation of the corresponding genes may lead to the characterization of gut-specific, inducible promoters, suitable for the expression of anti-parasitic agents in the gut of transgenic mosquitoes. We report here on the identification of a trypsin and a chymotrypsin gene family of Anopheles gambiae. Following a blood meal, the transcription of all members of the two identified gene clusters, seven trypsin genes (Antryp1-7) and two chymotrypsin genes (Anchym1-2), is induced. Recombinant Antryp1 and Antryp2, expressed in E. coli, were both active in vitro against blood proteins. Moreover, mouse sera raised against Antryp1, Anchym1 and Anchym2 recognized the corresponding proteases among the proteins of a lysate prepared from dissected guts of An. gambiae mosquitoes.

  • Abstract
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• Journal article
  MUGGLETON S, KING RD, STERNBERG MJE, 1993,

  PROTEIN SECONDARY STRUCTURE PREDICTION USING LOGIC-BASED MACHINE LEARNING

  , PROTEIN ENGINEERING, Vol: 6, Pages: 549-549, ISSN: 0269-2139
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  • Citations: 3
• Journal article
  HIRST JD, STERNBERG MJE, 1993,

  PREDICTION OF ATP-BINDING MOTIFS - A COMPARISON OF A PERCEPTRON-TYPE NEURAL-NETWORK AND A CONSENSUS SEQUENCE METHOD (VOL 4, PG 615, 1991)

  , PROTEIN ENGINEERING, Vol: 6, Pages: 549-554, ISSN: 0269-2139
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  • Citations: 1
• Journal article
  Müller HM, Scarselli E, Crisanti A, 1993,

  Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum in parasite-host cell interactions.

  , Parassitologia, Vol: 35 Suppl, Pages: 69-72, ISSN: 0048-2951

  Thrombospondin related anonymous protein (TRAP) of Plasmodium falciparum is characterized by the presence of an amino acid motif based on the sequence Trp-Ser-Pro-Cys-Ser-Val-Thr-Cys-Gly (WSPCSVTCG) that is found in a growing family of proteins. The sequence WSPCSVTCG is considered to confer sulpho-galactosyl-cerebroside (sulphatide) binding properties to antistasin, TSP, CS protein and properdin. The observation that TRAP is localized both on the micronemes and on the surface of P. falciparum sporozoites would suggest a role played by TRAP, and its putative sulphated glycoconjugates binding motif, in the recognition and/or entry of hepatocytes by the sporozoite. Our results indicated that TRAP constructs, expressed in E. coli, bind to sulpho-galactosyl-cerebrosides (sulphatides) and to the surface of HepG2 cells using the conserved amino acid motif WSPCSVTCG. Antisera raised against TRAP constructs inhibited sporozoite invasion of HepG2 cells thus suggesting, thus, that TRAP may be one of the parasite-encoded molecules implicated in the sporozoite invasion of hepatocytes. Moreover, the possibility that TRAP antibodies may be relevant in malaria immunity is supported by the results obtained in a prospective study conducted in a malaria endemic area. In adolescents, the presence of TRAP antibodies, before malaria transmission, correlated positively with the control of parasite density.

  • Abstract
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• Journal article
  KHOO KH, MORRIS HR, MCDOWELL RA, DELL A, MACCARANA M, LINDAHL Uet al., 1993,

  FABMS DERIVATIZATION STRATEGIES FOR THE ANALYSIS OF HEPARIN-DERIVED OLIGOSACCHARIDES

  , CARBOHYDRATE RESEARCH, Vol: 244, Pages: 205-223, ISSN: 0008-6215
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  • Citations: 34
• Journal article
  PICKETT SD, STERNBERG MJE, 1993,

  EMPIRICAL SCALE OF SIDE-CHAIN CONFORMATIONAL ENTROPY IN PROTEIN-FOLDING

  , JOURNAL OF MOLECULAR BIOLOGY, Vol: 231, Pages: 825-839, ISSN: 0022-2836
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  • Citations: 246
• Journal article
  PRENTICE IC, BARTLEIN PJ, WEBB T, 1993,

  VEGETATION AND CLIMATE-CHANGE IN EASTERN NORTH-AMERICA SINCE THE LAST GLACIAL MAXIMUM (VOL 72, PG 2038, 1993)

  , ECOLOGY, Vol: 74, Pages: 998-998, ISSN: 0012-9658
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  • Citations: 3
• Journal article
  SICILIANO RA, MORRIS HR, MCDOWELL RA, AZADI P, ROGERS ME, BENNETT HPJ, DELL Aet al., 1993,

  THE LEWIS-X EPITOPE IS A MAJOR NONREDUCING STRUCTURE IN THE SULFATED N-GLYCANS ATTACHED TO ASN-65 OF BOVINE PROOPIOMELANOCORTIN

  , GLYCOBIOLOGY, Vol: 3, Pages: 225-239, ISSN: 0959-6658
  • Author Web Link
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  • Citations: 42
• Journal article
  RANUCCI L, MULLER HM, LAROSA G, RECKMANN I, MORALES MAG, SPANO F, POZIO E, CRISANTI Aet al., 1993,

  CHARACTERIZATION AND IMMUNOLOCALIZATION OF A CRYPTOSPORIDIUM PROTEIN CONTAINING REPEATED AMINO-ACID MOTIFS

  , INFECTION AND IMMUNITY, Vol: 61, Pages: 2347-2356, ISSN: 0019-9567
  • Author Web Link
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  • Citations: 61
• Journal article
  KELLY CK, PURVIS A, 1993,

  SEED SIZE AND ESTABLISHMENT CONDITIONS IN TROPICAL TREES - ON THE USE OF TAXONOMIC RELATEDNESS IN DETERMINING ECOLOGICAL PATTERNS

  , OECOLOGIA, Vol: 94, Pages: 356-360, ISSN: 0029-8549
  • Author Web Link
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  • Citations: 92
• Journal article
  DRICKAMER K, 1993,

  CA2+-DEPENDENT CARBOHYDRATE-RECOGNITION DOMAINS IN ANIMAL PROTEINS

  , CURRENT OPINION IN STRUCTURAL BIOLOGY, Vol: 3, Pages: 393-400, ISSN: 0959-440X
  • Author Web Link
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  • Citations: 226
• Journal article
  PRENTICE IC, 1993,

  CLIMATE-CHANGE - PROCESS AND PRODUCTION

  , NATURE, Vol: 363, Pages: 209-210, ISSN: 0028-0836
  • Cite
  • Citations: 7
• Journal article
  SAMBASIVAM H, RASSOULI M, MURRAY RK, NAGPURKAR A, MOOKERJEA S, AZADI P, DELL A, MORRIS HRet al., 1993,

  STUDIES ON THE CARBOHYDRATE MOIETY AND ON THE BIOSYNTHESIS OF RAT C-REACTIVE PROTEIN

  , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 268, Pages: 10007-10016, ISSN: 0021-9258
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  • Citations: 15
• Journal article
  VERREY F, DRICKAMER K, 1993,

  DETERMINANTS OF OLIGOMERIC STRUCTURE IN THE CHICKEN LIVER GLYCOPROTEIN RECEPTOR

  , BIOCHEMICAL JOURNAL, Vol: 292, Pages: 149-155, ISSN: 0264-6021
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  • Citations: 12
• Journal article
  DYNLACHT BD, WEINZIERL ROJ, ADMON A, TJIAN Ret al., 1993,

  THE DTAF(II)80 SUBUNIT OF DROSOPHILA TFIID CONTAINS BETA-TRANSDUCIN REPEATS

  , NATURE, Vol: 363, Pages: 176-179, ISSN: 0028-0836
  • Author Web Link
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  • Citations: 118
• Journal article
  ZIMMERMANN JL, BOUSSAC A, RUTHERFORD AW, 1993,

  THE MANGANESE CENTER OF OXYGEN-EVOLVING AND CA2+-DEPLETED PHOTOSYSTEM .2. A PULSED EPR SPECTROSCOPY STUDY

  , BIOCHEMISTRY, Vol: 32, Pages: 4831-4841, ISSN: 0006-2960
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  • Citations: 60
• Journal article
  FRANKS NP, ABRAHAM MH, LIEB WR, 1993,

  MOLECULAR-ORGANIZATION OF LIQUID N-OCTANOL - AN X-RAY-DIFFRACTION ANALYSIS

  , JOURNAL OF PHARMACEUTICAL SCIENCES, Vol: 82, Pages: 466-470, ISSN: 0022-3549
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  • Citations: 92
• Journal article
  TAYLOR ME, 1993,

  RECOGNITION OF COMPLEX CARBOHYDRATES BY THE MACROPHAGE MANNOSE RECEPTOR

  , BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 21, Pages: 468-473, ISSN: 0300-5127
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  • Citations: 35
• Journal article
  DRICKAMER K, 1993,

  RECOGNITION OF COMPLEX CARBOHYDRATES BY CA2+-DEPENDENT ANIMAL LECTINS

  , BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 21, Pages: 456-459, ISSN: 0300-5127
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  • Citations: 47
• Journal article
  BERRIGAN D, CHARNOV EL, PURVIS A, HARVEY PHet al., 1993,

  PHYLOGENETIC CONTRASTS AND THE EVOLUTION OF MAMMALIAN LIFE-HISTORIES

  , EVOLUTIONARY ECOLOGY, Vol: 7, Pages: 270-278, ISSN: 0269-7653
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  • Citations: 22
• Journal article
  CHIPPINDALE AK, LEROI AM, KIM SB, ROSE MRet al., 1993,

  PHENOTYPIC PLASTICITY AND SELECTION IN DROSOPHILA LIFE-HISTORY EVOLUTION .1. NUTRITION AND THE COST OF REPRODUCTION

  , JOURNAL OF EVOLUTIONARY BIOLOGY, Vol: 6, Pages: 171-193, ISSN: 1010-061X
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  • Citations: 361
• Journal article
  SPANU P, BOLLER T, KENDE H, 1993,

  DIFFERENTIAL ACCUMULATION OF TRANSCRIPTS OF 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE GENES IN TOMATO PLANTS INFECTED WITH PHYTOPHTHORA-INFESTANS AND IN ELICITOR-TREATED TOMATO CELL-SUSPENSIONS

  , JOURNAL OF PLANT PHYSIOLOGY, Vol: 141, Pages: 557-562, ISSN: 0176-1617
  • Author Web Link
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  • Citations: 37

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