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  • Journal article
    BOUSSAC A, RUTHERFORD AW, 1988,

    NATURE OF THE INHIBITION OF THE OXYGEN-EVOLVING ENZYME OF PHOTOSYSTEM-II INDUCED BY NACL WASHING AND REVERSED BY THE ADDITION OF CA-2+ OR SR-2+

    , BIOCHEMISTRY, Vol: 27, Pages: 3476-3483, ISSN: 0006-2960
    • Cite
    • Citations: 238
  • Journal article
    BURT A, KRAMER DL, NAKATSURU K, SPRY Cet al., 1988,

    THE TEMPO OF REPRODUCTION IN HYPHESSOBRYCON-PULCHRIPINNIS (CHARACIDAE), WITH A DISCUSSION ON THE BIOLOGY OF MULTIPLE SPAWNING IN FISHES

    , ENVIRONMENTAL BIOLOGY OF FISHES, Vol: 22, Pages: 15-27, ISSN: 0378-1909
    • Cite
    • Citations: 91
  • Journal article
    SPANU P, BONFANTEFASOLO P, 1988,

    CELL-WALL-BOUND PEROXIDASE-ACTIVITY IN ROOTS OF MYCORRHIZAL ALLIUM-PORRUM

    , NEW PHYTOLOGIST, Vol: 109, Pages: 119-124, ISSN: 0028-646X
  • Journal article
    ERDJUMENT H, LANE DA, LOWE GDO, PANICO M, DIMARZO V, MORRIS HRet al., 1988,

    ANTITHROMBIN GLASGOW - SUBSTITUTION OF ARG393 TO HIS AT THE REACTIVE SITE

    , BRITISH JOURNAL OF HAEMATOLOGY, Vol: 69, Pages: 121-121, ISSN: 0007-1048
  • Journal article
    HILL BL, DRICKAMER K, BRODSKY FM, PARHAM Pet al., 1988,

    IDENTIFICATION OF THE PHOSPHORYLATION SITES OF CLATHRIN LIGHT CHAIN LCB

    , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 263, Pages: 5499-5501
    • Cite
    • Citations: 46
  • Journal article
    ERDJUMENT H, LANE DA, PANICO M, DIMARZO V, MORRIS HRet al., 1988,

    SINGLE AMINO-ACID SUBSTITUTIONS IN THE REACTIVE SITE OF ANTITHROMBIN LEADING TO THROMBOSIS - CONGENITAL SUBSTITUTION OF ARGININE-393 TO CYSTEINE IN ANTITHROMBIN NORTHWICK PARK AND TO HISTIDINE IN ANTITHROMBIN GLASGOW

    , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 263, Pages: 5589-5593
    • Cite
    • Citations: 85
  • Journal article
    STYRING S, RUTHERFORD AW, 1988,

    DEACTIVATION KINETICS AND TEMPERATURE-DEPENDENCE OF THE S-STATE TRANSITIONS IN THE OXYGEN-EVOLVING SYSTEM OF PHOTOSYSTEM-II MEASURED BY ELECTRON-PARAMAGNETIC-RES SPECTROSCOPY

    , BIOCHIMICA ET BIOPHYSICA ACTA, Vol: 933, Pages: 378-387, ISSN: 0006-3002
    • Cite
    • Citations: 141
  • Journal article
    DEMANGE P, BATEMAN A, DELL A, ABDALLAH MAet al., 1988,

    STRUCTURE OF AZOTOBACTIN D, A SIDEROPHORE OF AZOTOBACTER-VINELANDII STRAIN-D (CCM-289)

    , BIOCHEMISTRY, Vol: 27, Pages: 2745-2752, ISSN: 0006-2960
    • Cite
    • Citations: 69
  • Journal article
    MELLOW TE, HALBERG D, DRICKAMER K, 1988,

    ENDOCYTOSIS OF N-ACETYLGLUCOSAMINE-CONTAINING GLYCOPROTEINS BY RAT FIBROBLASTS EXPRESSING A SINGLE SPECIES OF CHICKEN LIVER GLYCOPROTEIN RECEPTOR

    , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 263, Pages: 5468-5473
    • Cite
    • Citations: 30
  • Journal article
    COATES ARM, COOKSON J, STERNBERG MJE, 1988,

    PREDICTION AND COMPARISON OF ANTIGENIC DETERMINANTS OF HUMAN AND MONKEY AIDS VIRUSES

    , JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 25, Pages: R18-R19, ISSN: 0022-2615
  • Journal article
    FUKUDA MN, DELL A, SCARTEZZINI P, 1988,

    DEFECT IN N-ACETYLGLUCOSAMINYLTRANSFERASE-II (GNT-II) IN HEPATOCYTE AND LYMPHOCYTE-B OF CONGENITAL DYSERYTHROPOIETIC ANEMIA TYPE-II (HEMPAS)

    , FASEB JOURNAL, Vol: 2, Pages: A560-A560, ISSN: 0892-6638
  • Journal article
    LINDBERG B, LEONTEIN K, LINDQUIST U, SVENSON SB, WRANGSELL G, DELL A, ROGERS Met al., 1988,

    STRUCTURAL STUDIES OF THE O-ANTIGEN POLYSACCHARIDE OF SALMONELLA-THOMPSON, SEROGROUP-C1 (6,7)

    , CARBOHYDRATE RESEARCH, Vol: 174, Pages: 313-322, ISSN: 0008-6215
    • Cite
    • Citations: 47
  • Journal article
    YORK WS, OATES JE, VANHALBEEK H, DARVILL AG, ALBERSHEIM P, TILLER PR, DELL Aet al., 1988,

    STRUCTURE OF PLANT-CELL WALLS .21. LOCATION OF THE ORTHO-ACETYL SUBSTITUENTS ON A NONASACCHARIDE REPEATING UNIT OF SYCAMORE EXTRACELLULAR XYLOGLUCAN

    , CARBOHYDRATE RESEARCH, Vol: 173, Pages: 113-132, ISSN: 0008-6215
    • Cite
    • Citations: 67
  • Journal article
    MORRIS HR, MASENTO MS, TAYLOR GW, JERMYN KA, KAY RRet al., 1988,

    STRUCTURE ELUCIDATION OF 2 DIFFERENTIATION INDUCING FACTORS (DIF-2 AND DIF-3) FROM THE CELLULAR SLIME-MOLD DICTYOSTELIUM-DISCOIDEUM

    , BIOCHEMICAL JOURNAL, Vol: 249, Pages: 903-906, ISSN: 0264-6021
    • Cite
    • Citations: 91
  • Journal article
    RUTHERFORD AW, SEIBERT M, METZ JG, 1988,

    CHARACTERIZATION OF THE LOW-FLUORESCENT (LF1) MUTANT OF SCENEDESMUS BY ELECTRON-PARAMAGNETIC-RES

    , BIOCHIMICA ET BIOPHYSICA ACTA, Vol: 932, Pages: 171-176, ISSN: 0006-3002
    • Cite
    • Citations: 31
  • Journal article
    DIMARZO V, TIPPINS JR, GALADARI SHI, MORRIS HRet al., 1988,

    NEUROPEPTIDES AND LEUKOTRIENE BIOSYNTHESIS - THE EFFECT OF CALCITONIN, PEPTIDE HISTIDINE VALINE-42, HELODERMIN, NEUROPEPTIDE-Y AND GALANIN

    , NEUROPEPTIDES, Vol: 11, Pages: 169-172, ISSN: 0143-4179
  • Journal article
    Rutherford AW, Seibert M, Metz JG, 1988,

    Characterisation of the low-fluorescent (LF1) mutant of Scenedesmus by EPR

    , Bba Bioenergetics, Vol: 932, Pages: 171-176, ISSN: 0005-2728

    An EPR study of the low fluorescent mutant, LF1, of the green alga, Scenedesmus obliquus, has been performed and the following results were obtained. (1) Stable photoinduced charge separation occurs at low temperature forming the characteristic EPR signals from Q<sup>-</sup><inf>A</inf>Fe<sup>2+</sup>, the primary semiquinone-iron complex, indicating no major structural modification of the electron acceptor complex in the LF1 mutant. (2) The source of the electron in this reaction at 200 K is a component, probably a chlorophyll molecule, which gives rise to an EPR signal at g ≈ 2.0026 when photooxidized; in the wild type the S<inf>2</inf> manganese multiline EPR signal is generated under these conditions. (3) Contrary to a previous report (Biochim. Biophys. Acta 682 (1982) 106-114), Signal II is present in the dark in LF1; however, it exhibits different microwave power saturation characteristics from those of Signal II in the wild type. These results show that the LF1 mutant has a functional reaction centre which lacks the redox active manganese of the O<inf>2</inf>-evolving enzyme. In addition, as reported previously, cytochrome b-559 is in the low-potential, oxidized form in LF1, while it is largely in the high-potential, reduced form in the wild-type. This effect is thought to be only indirectly related to the 34 kDa to the 36 kDa change in D<inf>1</inf> polypeptide size, which is assumed to be responsible for the lack of Mn binding in the LF1 mutant. © 1988.
  • Journal article
    Cramer W, Prentice IC, 1988,

    Simulation of regional soil moisture deficits on a European scale

    , Norsk Geografisk Tidsskrift, Vol: 42, Pages: 149-151, ISSN: 0029-1951

    A simple deterministic simulation model for landscape-scale soil water deficits has been developed. Standard weather station data are used to estimate ‘daily’ precipitation and actual (regional) evapo- ranspiration (AET). The balance is added to soil moisture, which is accounted by a simple bucket nodel. AET is the daily integral of the lesser of supply and demand: Supply is governed by current oil moisture, demand by estimated net radiation and temperature. The model estimates geographical atterns of soil water deficit at a scale suitable for comparison with the distributions of plant species md vegetation types. The model provides a way of quantifying soil moisture stress in biogeographical esearch. © 1988 Taylor & Francis Group, LLC.
  • Journal article
    Marino G, Pucci P, Malorni A, Morris HRet al., 1988,

    Analysis of post-translational modifications by FAB mass spectrometry.

    , Adv Exp Med Biol, Vol: 231, Pages: 651-657, ISSN: 0065-2598
  • Journal article
    RK Poole, HD Williams, 1988,

    Formation of a 680 nm absorbing form of the cytochrome bd oxidase complex of Escherichia coli by reaction of hydrogen peroxide with the ferric form

    , FEBS Letters, Vol: 231, Pages: 243-246
  • Journal article
    HD Williams, RK Poole, 1988,

    Cytochromes Acetobacter pasteurianus NCIB 6428: Reaction with oxygen of cytochrome o in cells, membranes, and non-sedimentable subcellular fractions

    , Current Microbiology, Vol: 16, Pages: 277-280
  • Journal article
    CRISANTI A, LAPERA G, LENZI A, GANDINI L, DONDERO F, SPAGNOLI L, DISILVERIO Fet al., 1988,

    STUDY ON AUTO-ANTIGENS OF SPERM CELL-SURFACE - PRELIMINARY DATA ON BIOCHEMICAL-ANALYSIS

    , EOS-RIVISTA DI IMMUNOLOGIA ED IMMUNOFARMACOLOGIA, Vol: 8, Pages: 274-277, ISSN: 0392-6699
  • Book chapter
    Postma PW, Broekhuizen CP, Schuitema A, Vogler AP, Lengeler JWet al., 1988,

    Carbohydrate transport and metabolism in Escherichia coli and Salmonella typhimurium: regulation by the PEP:Carbohydrate Phosphotransferase System. In: Molecular basis of biomembrane transport

    , Molecular basis of biomembrane transport, Editors: Palmieri, Quagliariello, Pages: 43-52
  • Journal article
    KAY RR, BERKS M, TRAYNOR D, TAYLOR GW, MASENTO MS, MORRIS HRet al., 1988,

    SIGNALS CONTROLLING CELL-DIFFERENTIATION AND PATTERN-FORMATION IN DICTYOSTELIUM

    , DEVELOPMENTAL GENETICS, Vol: 9, Pages: 579-587, ISSN: 0192-253X
  • Journal article
    FUKUDA MN, MASRI K, DELL A, 1988,

    DEFECT IN GALACTOSYLTRANSFERASE (GT) FOUND IN A VARIANT OF CONGENITAL DYSERYTHROPOIETIC ANEMIA TYPE-II (HEMPAS) PATIENT

    , GLYCOCONJUGATE JOURNAL, Vol: 5, Pages: 332-332, ISSN: 0282-0080
  • Journal article
    Levitan ES, Schofield PR, Burt DR, Rhee LM, Wisden W, Kohler M, Fujita N, Rodriguez HF, Stephenson A, Darlison MG, Barnard EA, Seeburg PHet al., 1988,

    Structural and functional basis for GABAA receptor heterogeneity

    , Nature, Vol: 335, Pages: 76-79, ISSN: 0028-0836

    When gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in vertebrate brain, binds to its receptor it activates a chloride channel. Neurotransmitter action at the GABAA receptor is potentiated by both benzodiazepines and barbiturates which are therapeutically useful drugs (reviewed in ref. 1). There is strong evidence that this receptor is heterogeneous. We have previously isolated complementary DNAs encoding an alpha- and a beta-subunit and shown that both are needed for expression of a functional GABAA receptor. We have now isolated cDNAs encoding two additional GABAA receptor alpha-subunits, confirming the heterogeneous nature of the receptor/chloride channel complex and demonstrating a molecular basis for it. These alpha-subunits are differentially expressed within the CNS and produce, when expressed with the beta-subunit in Xenopus oocytes, receptor subtypes which can be distinguished by their apparent sensitivity to GABA. Highly homologous receptor subtypes which differ functionally seem to be a common feature of brain receptors.
  • Journal article
    Wisden W, Morris BJ, Darlison MG, Hunt SP, Barnard EAet al., 1988,

    Distinct GABAA receptor alpha subunit mRNAs show differential patterns of expression in bovine brain

    , Neuron, Vol: 1, Pages: 937-947, ISSN: 0896-6273

    Specific oligonucleotide probes have been used to visualize the regional and cellular distribution of the mRNAs encoding three structurally distinct GABAA receptor alpha subunits in bovine brain. In situ hybridization analysis showed that these transcripts differ in distribution and in relative abundance. In frontal cortex the alpha 1 and alpha 2 transcripts are most abundant in layers II-IV, whereas the alpha 3 mRNA is most abundant in layers V and VI. In the hippocampal complex, the alpha transcripts are differentially distributed in the entorhinal cortex and subiculum. The alpha 2 transcript is enriched in the dentate gyrus and CA4/CA3 regions of the hippocampus. In the cerebellum, essentially only the alpha 1 transcript is detectable in granule cells, Purkinje cells, and stellate/basket cells. These results suggest that the different alpha subunits represent components of distinct GABAA receptor subtypes.
  • Journal article
    TERBRAAK CJF, PRENTICE IC, 1988,

    A THEORY OF GRADIENT ANALYSIS

    , ADVANCES IN ECOLOGICAL RESEARCH, Vol: 18, Pages: 271-317, ISSN: 0065-2504
    • Cite
    • Citations: 156
  • Journal article
    Bartoloni A, Pizza M, Gross R, Perugini M, Arico B, Domenighini M, Rappuoli Ret al., 1988,

    Engineering bacterial toxin for the development of new vaccine against pertussis.

    , Tokai J Exp Clin Med, Vol: 13 Suppl, Pages: 217-222, ISSN: 0385-0005

    Bordetella pertussis is the causative agent of whooping cough. The cellular pertussis vaccine introduced in the forties is highly effective and is widely used, but its reactogenicity has led to public concern regarding its safety. The attempts to reduce the side effects associated with pertussis immunization have led to the preparation of acellular B. pertussis products: one composed of detoxified pertussis toxin (PT) and filamentous haemagglutinin (FHA), another one composed only of detoxified PT and a third vaccine composed of detoxified PT, FHA and serotypes 1, 3 of fimbriae. In our laboratories we have approached the study of pertussis toxin, the molecule present in all the proposed acellular pertussis vaccines and one of the main virulence factors of B. Pertussis, with the aim of producing new acellular pertussis vaccines by using recombinant DNA techniques.
  • Journal article
    CAIRNS MT, ALVAREZ J, PANICO M, GIBBS AF, MORRIS HR, CHAPMAN D, BALDWIN SAet al., 1987,

    INVESTIGATION OF THE STRUCTURE AND FUNCTION OF THE HUMAN-ERYTHROCYTE GLUCOSE TRANSPORTER BY PROTEOLYTIC DISSECTION

    , BIOCHIMICA ET BIOPHYSICA ACTA, Vol: 905, Pages: 295-310, ISSN: 0006-3002
    • Cite
    • Citations: 98

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