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• Journal article
  FRANKS NP, LIEB WR, 1987,

  WHAT IS THE MOLECULAR NATURE OF GENERAL ANESTHETIC TARGET SITES

  , TRENDS IN PHARMACOLOGICAL SCIENCES, Vol: 8, Pages: 169-174, ISSN: 0165-6147
  • Author Web Link
  • Cite
  • Citations: 169
• Journal article
  TAYLOR ME, LEANING MS, SUMMERFIELD JA, 1987,

  UPTAKE AND PROCESSING OF GLYCOPROTEINS BY RAT HEPATIC MANNOSE RECEPTOR

  , AMERICAN JOURNAL OF PHYSIOLOGY, Vol: 252, Pages: E690-E698, ISSN: 0002-9513
  • Cite
  • Citations: 18
• Journal article
  REES MCP, DIMARZO V, TIPPINS JR, MORRIS HR, TURNBULL ACet al., 1987,

  LEUKOTRIENE RELEASE BY HUMAN-FETAL MEMBRANES, DECIDUA AND PLACENTA

  , BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol: 23, Pages: P637-P638, ISSN: 0306-5251
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• Journal article
  POST MJD, QUENCER RM, GREEN BA, MONTALVO BM, TOBIAS JA, SOWERS JJ, LEVIN IHet al., 1987,

  INTRAMEDULLARY SPINAL-CORD METASTASES, MAINLY OF NONNEUROGENIC ORIGIN

  , AMERICAN JOURNAL OF ROENTGENOLOGY, Vol: 148, Pages: 1015-1022, ISSN: 0361-803X
  • Cite
• Journal article
  PRENTICE IC, VANDERMAAREL E, 1987,

  THEORY AND MODELS IN VEGETATION SCIENCE - PROCEEDINGS OF THE SYMPOSIUM THEORY AND MODELS IN VEGETATION SCIENCE HELD IN UPPSALA, JULY 8-13, 1985 - PREFACE

  , VEGETATIO, Vol: 69, Pages: 3-3, ISSN: 0042-3106
  • Author Web Link
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  • Citations: 1
• Journal article
  LEEMANS R, PRENTICE IC, 1987,

  DESCRIPTION AND SIMULATION OF TREE-LAYER COMPOSITION AND SIZE DISTRIBUTIONS IN A PRIMEVAL PICEA-PINUS FOREST

  , VEGETATIO, Vol: 69, Pages: 147-156, ISSN: 0042-3106
  • Cite
  • Citations: 75
• Journal article
  BURT A, BELL G, 1987,

  MAMMALIAN CHIASMA FREQUENCIES AS A TEST OF 2 THEORIES OF RECOMBINATION

  , NATURE, Vol: 326, Pages: 803-805, ISSN: 0028-0836
  • Cite
  • Citations: 180
• Journal article
  COATES ARM, COOKSON J, BARTON GJ, ZVELEBIL MJ, STERNBERG MJEet al., 1987,

  AIDS VACCINE PREDICTIONS

  , NATURE, Vol: 326, Pages: 549-550, ISSN: 0028-0836
  • Author Web Link
  • Cite
  • Citations: 47
• Journal article
  KAMISANGO K, DELL A, BALLOU CE, 1987,

  BIOSYNTHESIS OF THE MYCOBACTERIAL O-METHYLGLUCOSE LIPOPOLYSACCHARIDE - CHARACTERIZATION OF PUTATIVE INTERMEDIATES IN THE INITIATION, ELONGATION, AND TERMINATION REACTIONS

  , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 262, Pages: 4580-4586
  • Cite
  • Citations: 29
• Journal article
  BLUNDELL TL, SIBANDA BL, STERNBERG MJE, THORNTON JMet al., 1987,

  KNOWLEDGE-BASED PREDICTION OF PROTEIN STRUCTURES AND THE DESIGN OF NOVEL MOLECULES

  , NATURE, Vol: 326, Pages: 347-352, ISSN: 0028-0836
  • Author Web Link
  • Cite
  • Citations: 586
• Journal article
  JACKSON AP, SEOW HF, HOLMES N, DRICKAMER K, PARHAM Pet al., 1987,

  CLATHRIN LIGHT-CHAINS CONTAIN BRAIN-SPECIFIC INSERTION SEQUENCES AND A REGION OF HOMOLOGY WITH INTERMEDIATE FILAMENTS

  , NATURE, Vol: 326, Pages: 154-159, ISSN: 0028-0836
  • Author Web Link
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  • Citations: 128
• Journal article
  BRODSKY FM, GALLOWAY CJ, BLANK GS, JACKSON AP, SEOW HF, DRICKAMER K, PARHAM Pet al., 1987,

  LOCALIZATION OF CLATHRIN LIGHT-CHAIN SEQUENCES MEDIATING HEAVY-CHAIN BINDING AND COATED VESICLE DIVERSITY

  , NATURE, Vol: 326, Pages: 203-205, ISSN: 0028-0836
  • Author Web Link
  • Cite
  • Citations: 61
• Journal article
  LOEB JA, DRICKAMER K, 1987,

  THE CHICKEN RECEPTOR FOR ENDOCYTOSIS OF GLYCOPROTEINS CONTAINS A CLUSTER OF N-ACETYLGLUCOSAMINE-BINDING SITES

  , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 262, Pages: 3022-3029
  • Cite
  • Citations: 66
• Journal article
  PRENTICE IC, BERGLUND BE, OLSSON T, 1987,

  QUANTITATIVE FOREST-COMPOSITION SENSING CHARACTERISTICS OF POLLEN SAMPLES FROM SWEDISH LAKES

  , BOREAS, Vol: 16, Pages: 43-54, ISSN: 0300-9483
  • Cite
  • Citations: 102
• Journal article
  BRYANT SH, STERNBERG MJE, 1987,

  COMPARISON OF PROTEIN STRUCTURAL PROFILES BY INTERACTIVE COMPUTER-GRAPHICS

  , JOURNAL OF MOLECULAR GRAPHICS, Vol: 5, Pages: 4-&, ISSN: 0263-7855
  • Author Web Link
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  • Citations: 8
• Journal article
  PRENTICE IC, VANTONGEREN O, DESMIDT JT, 1987,

  SIMULATION OF HEATHLAND VEGETATION DYNAMICS

  , JOURNAL OF ECOLOGY, Vol: 75, Pages: 203-219, ISSN: 0022-0477
  • Cite
  • Citations: 13
• Journal article
  DRICKAMER K, MCCREARY V, 1987,

  EXON STRUCTURE OF A MANNOSE-BINDING PROTEIN GENE REFLECTS ITS EVOLUTIONARY RELATIONSHIP TO THE ASIALOGLYCOPROTEIN RECEPTOR AND NONFIBRILLAR COLLAGENS

  , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 262, Pages: 2582-2589
  • Cite
  • Citations: 84
• Journal article
  LU DP, BALLOU CE, DEFAYE J, DELL Aet al., 1987,

  SYNTHESIS OF 6-DEOXYMALTOOLIGOSACCHARIDES AND A STUDY OF THEIR LIPID-BINDING PROPERTIES

  , CARBOHYDRATE RESEARCH, Vol: 160, Pages: 171-184, ISSN: 0008-6215
  • Cite
  • Citations: 7
• Journal article
  BEIJER C, RUTHERFORD AW, 1987,

  THE IRON-QUINONE ACCEPTOR COMPLEX IN RHODOSPIRILLUM-RUBRUM CHROMATOPHORES STUDIED BY ELECTRON-PARAMAGNETIC-RES

  , BIOCHIMICA ET BIOPHYSICA ACTA, Vol: 890, Pages: 169-178, ISSN: 0006-3002
  • Cite
  • Citations: 23
• Journal article
  BARTON GJ, STERNBERG MJE, 1987,

  EVALUATION AND IMPROVEMENTS IN THE AUTOMATIC ALIGNMENT OF PROTEIN SEQUENCES

  , PROTEIN ENGINEERING, Vol: 1, Pages: 89-94, ISSN: 0269-2139
  • Cite
  • Citations: 105
• Journal article
  VOGLER AP, LENGELER JW, 1987,

  INDIRECT ROLE OF ADENYLATE-CYCLASE AND CYCLIC-AMP IN CHEMOTAXIS TO PHOSPHOTRANSFERASE SYSTEM CARBOHYDRATES IN ESCHERICHIA-COLI K-12

  , JOURNAL OF BACTERIOLOGY, Vol: 169, Pages: 593-599, ISSN: 0021-9193
  • Cite
  • Citations: 22
• Journal article
  STYRING S, MIYAO M, RUTHERFORD AW, 1987,

  FORMATION AND FLASH-DEPENDENT OSCILLATION OF THE S2-STATE MULTILINE ELECTRON-PARAMAGNETIC-RES SIGNAL IN AN OXYGEN-EVOLVING PHOTOSYSTEM-II PREPARATION LACKING THE 3 EXTRINSIC PROTEINS IN THE OXYGEN-EVOLVING SYSTEM

  , BIOCHIMICA ET BIOPHYSICA ACTA, Vol: 890, Pages: 32-38, ISSN: 0006-3002
  • Cite
  • Citations: 27
• Journal article
  Mathis P, Rutherford AW, 1987,

  The Primary Reactions of Photosystems I and II of Algae and Higher Plants

  , New Comprehensive Biochemistry, Vol: 15, Pages: 63-96, ISSN: 0167-7306

  This chapter discusses the primary reactions of photosystems I and II of algae and higher plants. In photosynthetic organisms, the “primary reactions” fulfil the objective of converting the energy of light into a primary form of chemical energy which lasts for a time compatible with ordinary biochemical processes—that is, milliseconds. In these reactions, a rather large fraction, approximately 40%, of the photon energy is stored as chemical free energy. The primary reactions can be viewed from two major perspectives. Firstly, from a photochemical point of view: pigment molecules are excited to their lowest excited singlet state, which reacts in an electron transfer reaction, the first step of a process of charge separation. Secondly, from a biochemical point of view the reactions take place in highly organized complexes, the reaction centres, which are made up of several classes of molecules that cooperate in fulfilling complementary roles, such as: architectural support, light absorption, energy transfer and electron transfer. All oxygenic organisms, ranging from cyanobacteria to algae and higher plants, contain photosystem I (PS I) and PS II reaction centres, with only minor variations in spite of their large taxonomic and ecological diversity. © 1987, Elsevier B.V. All rights reserved.

  • Abstract
  • Cite
  • Citations: 36
• Journal article
  Bryant SH, Sternberg MJE, 1987,

  Colour plates

  , Journal of Molecular Graphics, Vol: 5, Pages: 25-28, ISSN: 0263-7855
  • Cite
• Journal article
  Taylor ME, Leaning MS, Summerfield JA, 1987,

  Uptake and processing of glycoproteins by rat hepatic mannose receptor

  , American Journal of Physiology Endocrinology and Metabolism, Vol: 252, Pages: E690-E698, ISSN: 0193-1849

  A linear compartmental model has been developed for the in vivo metabolism of glycoproteins. The model is applied to the interpretation of dynamic data from the rat on agalactoorosomucoid (AGOR), an N-acetylglucosamine (GlcNAc)-terminated glycoprotein, and three neoglycoproteins terminating in mannose [mannose³⁶-bovine serum albumin (Man-BSA)] or glucose [maltose²⁹-BSA (Mal²⁹-BSA) and maltose⁸-BSA (Mal⁸-BSA)]. All of these proteins are taken up by the Man/GlcNAc receptor on hepatic sinusoidal cells. The rate of uptake was found to be determined by sugar type (Man-BSA, 0.78 min^-1 > Mal²⁹-BSA, 0.13 min^-1), sugar density (Mal²⁹-BSA > Mal⁸-BSA), and the geometry of the sugar display (AGOR, 0.51 min^-1 > Mal²⁹-BSA). Intracellular transport from the cell membrane to the lysosomes was slower for Man-BSA (~3 min) than for the other ligands (~0 min), suggesting that receptor-ligand uncoupling was slower for Man-BSA for which the receptor had the highest affinity or that extralysosomal catabolism of the other ligands occurred. Catabolism was also determined by the carbohydrate moiety of the ligand; it was greater for Mal²⁹-BSA and Mal⁸-BSA (≥0.8 min^-1) than for Man-BSA (0.27 min^-1), and AGOR, with a complex oligosaccharide, was most resistant to degradation (0.14 min^-1). An understanding of these structural features of glycoproteins that influence hepatic uptake, transport, and catabolism will be of value in drug targeting and for enzyme replacement in lysosomal storage disorders. Special emphasis is placed on model identifiability before experimentation as an aid in experiment des

  • Abstract
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  • Citations: 15
• Journal article
  DIMARZO V, TIPPINS JR, MORRIS HR, 1987,

  NEUROPEPTIDES AND LEUKOTRIENE RELEASE - EFFECT OF PEPTIDE HISTIDINE ISOLEUCINE AND SECRETIN IN PLATELET ACTIVATING FACTOR-STIMULATED RAT LUNG

  , NEUROPEPTIDES, Vol: 9, Pages: 51-58, ISSN: 0143-4179
  • Author Web Link
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  • Citations: 10
• Journal article
  LAFERTE S, FUKUDA MN, FUKUDA M, DELL A, DENNIS JWet al., 1987,

  GLYCOSPHINGOLIPIDS OF LECTIN-RESISTANT MUTANTS OF THE HIGHLY METASTATIC MOUSE-TUMOR CELL-LINE, MDAY-D2

  , CANCER RESEARCH, Vol: 47, Pages: 150-159, ISSN: 0008-5472
  • Cite
  • Citations: 38
• Journal article
  HD Williams, RK Poole, 1987,

  Low temperature spectrophotometric studies of cytochromes a1 and d in Acetobacter pasteurianus (NCIB 6428)

  , Biochemical Society Transactions, Vol: 14, Pages: 1215-1216
  • Cite
• Journal article
  ZAIDI M, CHAMBERS TJ, TIPPINS J, MORRIS HR, MACINTYRE Iet al., 1987,

  STRUCTURAL MODIFICATIONS OF HUMAN CGRP AND THEIR EFFECT ON OSTEOCLASTIC BONE-RESORPTION

  , BONE, Vol: 8, Pages: 265-265, ISSN: 8756-3282
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• Journal article
  Tippins JR, Di Marzo V, Morris HR, 1987,

  Effect of vasoactive intestinal peptide and calcitonin gene-related peptide on leukotriene release from guinea pig and rat lung.

  , Adv Prostaglandin Thromboxane Leukot Res, Vol: 17B, Pages: 1028-1032, ISSN: 0732-8141
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