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• Journal article
  DELL A, TILLER PR, 1986,

  A NOVEL MASS-SPECTROMETRIC PROCEDURE TO RAPIDLY DETERMINE THE POSITION OF O-ACYLATED RESIDUES IN THE SEQUENCE OF NATURALLY-OCCURRING OLIGOSACCHARIDES

  , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 135, Pages: 1126-1134, ISSN: 0006-291X
  • Cite
  • Citations: 34
• Journal article
  VINSON GP, WHITEHOUSE BJ, BATEMAN A, DELL Aet al., 1986,

  ACTIONS OF N-TERMINAL FRAGMENTS OF ACTH ON STEROIDOGENESIS IN RAT ADRENAL-CELLS

  , JOURNAL OF ENDOCRINOLOGY, Vol: 108, Pages: 125-125, ISSN: 0022-0795
  • Author Web Link
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• Journal article
  VANTONGEREN O, PRENTICE IC, 1986,

  A SPATIAL SIMULATION-MODEL FOR VEGETATION DYNAMICS

  , VEGETATIO, Vol: 65, Pages: 163-173, ISSN: 0042-3106
  • Author Web Link
  • Cite
  • Citations: 41
• Journal article
  LAFERTE S, FUKUDA M, FUKUDA MN, DELL A, DENNIS JWet al., 1986,

  STRUCTURES OF GLYCOSPHINGOLIPIDS OF THE METASTATIC MOUSE-TUMOR MDAY-D2 AND ITS NONMETASTATIC LECTIN-RESISTANT MUTANT MDW4

  , PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, Vol: 27, Pages: 1-1, ISSN: 0197-016X
  • Author Web Link
  • Cite
  • Citations: 2
• Journal article
  FUKUDA MN, DELL A, TILLER PR, VARKI A, KLOCK JC, FUKUDA Met al., 1986,

  STRUCTURE OF A NOVEL SIALYLATED FUCOSYL LACTO-N-NOR-HEXAOSYLCERAMIDE ISOLATED FROM CHRONIC MYELOGENOUS LEUKEMIA-CELLS

  , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 261, Pages: 2376-2383
  • Cite
  • Citations: 50
• Journal article
  TIPPINS JR, DIMARZO V, PANICO M, MORRIS HR, MACINTYRE Iet al., 1986,

  INVESTIGATION OF THE STRUCTURE ACTIVITY RELATIONSHIP OF HUMAN CALCITONIN GENE-RELATED PEPTIDE (CGRP)

  , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 134, Pages: 1306-1311, ISSN: 0006-291X
  • Cite
  • Citations: 72
• Journal article
  RAMMENSEE HG, ROBINSON PJ, CRISANTI A, BEVAN MJet al., 1986,

  RESTRICTED RECOGNITION OF BETA-2-MICROGLOBULIN BY CYTOTOXIC LYMPHOCYTES-T

  , NATURE, Vol: 319, Pages: 502-504, ISSN: 0028-0836
  • Author Web Link
  • Cite
  • Citations: 63
• Journal article
  ABRAHAM D, DANIEL P, DELL A, OATES J, SIDEBOTHAM R, WINCHESTER Bet al., 1986,

  STRUCTURAL-ANALYSIS OF THE MAJOR URINARY OLIGOSACCHARIDES IN FELINE ALPHA-MANNOSIDOSIS

  , BIOCHEMICAL JOURNAL, Vol: 233, Pages: 899-904, ISSN: 0264-6021
  • Cite
  • Citations: 26
• Journal article
  MELTON LD, MCNEIL M, DARVILL AG, ALBERSHEIM P, DELL Aet al., 1986,

  STRUCTURE OF PLANT-CELL WALLS .17. STRUCTURAL CHARACTERIZATION OF OLIGOSACCHARIDES ISOLATED FROM THE PECTIC POLYSACCHARIDE RHAMNOGALACTURONAN-II

  , CARBOHYDRATE RESEARCH, Vol: 146, Pages: 279-305, ISSN: 0008-6215
  • Cite
  • Citations: 51
• Journal article
  MCNEIL M, DARVILL J, DARVILL AG, ALBERSHEIM P, VANVEEN R, HOOYKAAS P, SCHILPEROORT R, DELL Aet al., 1986,

  HOST SYMBIONT INTERACTIONS .15. THE DISCERNIBLE, STRUCTURAL FEATURES OF THE ACIDIC POLYSACCHARIDES SECRETED BY DIFFERENT RHIZOBIUM SPECIES ARE THE SAME

  , CARBOHYDRATE RESEARCH, Vol: 146, Pages: 307-326, ISSN: 0008-6215
  • Cite
  • Citations: 65
• Journal article
  RUTHERFORD AW, 1986,

  HOW CLOSE IS THE ANALOGY BETWEEN THE REACTION CENTER OF PHOTOSYSTEM-II AND THAT OF PURPLE BACTERIA

  , BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 14, Pages: 15-17, ISSN: 0300-5127
  • Author Web Link
  • Cite
  • Citations: 67
• Journal article
  DAVIS KR, DARVILL AG, ALBERSHEIM P, DELL Aet al., 1986,

  HOST-PATHOGEN INTERACTIONS .29. OLIGOGALACTURONIDES RELEASED FROM SODIUM POLYPECTATE BY ENDOPOLYGALACTURONIC ACID LYASE ARE ELICITORS OF PHYTOALEXINS IN SOYBEAN

  , PLANT PHYSIOLOGY, Vol: 80, Pages: 568-577, ISSN: 0032-0889
  • Cite
  • Citations: 141
• Journal article
  GREENWALD SE, LEVER MJ, MACINTYRE I, MORRIS HR, TIPPINS JRet al., 1986,

  THE EFFECT OF HUMAN CALCITONIN GENE-RELATED PEPTIDE (CGRP) ON THE PIG CORONARY CIRCULATION

  , JOURNAL OF PHYSIOLOGY-LONDON, Vol: 371, Pages: P67-P67, ISSN: 0022-3751
  • Author Web Link
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• Journal article
  HOLLAND EC, DRICKAMER K, 1986,

  SIGNAL RECOGNITION PARTICLE MEDIATES THE INSERTION OF A TRANSMEMBRANE PROTEIN WHICH HAS A CYTOPLASMIC NH2 TERMINUS

  , JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 261, Pages: 1286-1292
  • Cite
  • Citations: 48
• Journal article
  ELLIOTT JR, HAYDON DA, 1986,

  MAPPING OF GENERAL ANESTHETIC TARGET SITES

  , NATURE, Vol: 319, Pages: 77-78, ISSN: 0028-0836
  • Author Web Link
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  • Citations: 14
• Journal article
  Prentice IC, Webb T, 1986,

  Pollen percentages, tree abundances and the Fagerlind effect

  , Journal of Quaternary Science, Vol: 1, Pages: 35-43, ISSN: 0267-8179

  Pollen diagrams traditionally are read as if pollen percentages were linearly related to relative tree abundances, although the slopes and intercepts of these relationships are accepted to differ among taxa. Corresponding map patterns of modern pollen and tree percentages support this assumption of linearity, which also underlies the use of linear regression on percentage data for pollen‐tree calibration. Fagerlind, however, showed that the theoretical relationship need not be linear and may be confounded by interdependencies among taxa. Regressions and scatter plots of modern pollen and tree percentages are here compared with results of extended R‐value (ERV) models, which correct for the ‘Fagerlind effect’. Three data sets from Wisconsin and Michigan, USA illustrate that regression coefficients provide a first approximation to their ERV equivalents, but scatter plots derived from the ERV analyses show reduced scatter about linearised relationships. Copyright © 1986 John Wiley & Sons, Ltd

  • Abstract
  • Cite
  • Citations: 141
• Journal article
  RUTHERFORD AW, ACKER S, 1986,

  ORIENTATION OF THE PRIMARY DONOR IN ISOLATED PHOTOSYSTEM-II REACTION CENTERS STUDIED BY ELECTRON-PARAMAGNETIC RESONANCE

  , BIOPHYSICAL JOURNAL, Vol: 49, Pages: 101-102, ISSN: 0006-3495
  • Author Web Link
  • Cite
  • Citations: 7
• Journal article
  POST MJD, SHELDON JJ, HENSLEY GT, SOILA K, TOBIAS JA, CHAN JC, QUENCER RM, MOSKOWITZ LBet al., 1986,

  CENTRAL-NERVOUS-SYSTEM DISEASE IN ACQUIRED-IMMUNODEFICIENCY-SYNDROME - PROSPECTIVE CORRELATION USING CT, MR IMAGING, AND PATHOLOGICAL-STUDIES

  , RADIOLOGY, Vol: 158, Pages: 141-148, ISSN: 0033-8419
  • Cite
• Journal article
  BARTLEIN PJ, PRENTICE IC, WEBB T, 1986,

  CLIMATIC RESPONSE SURFACES FROM POLLEN DATA FOR SOME EASTERN NORTH-AMERICAN TAXA

  , JOURNAL OF BIOGEOGRAPHY, Vol: 13, Pages: 35-57, ISSN: 0305-0270
  • Author Web Link
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  • Citations: 250
• Conference paper
  TOBIAS JA, CAIN JR, SOILA KP, SHELDON JPet al., 1986,

  USEFULNESS OF MAGNETIC-RESONANCE-IMAGING (MRI) IN THE DIAGNOSIS OF RENAL-VEIN THROMBOSIS (RVT)

  , Publisher: ELSEVIER SCIENCE INC, Pages: 206-206, ISSN: 0085-2538
  • Cite
• Journal article
  TURNBULL CGN, CROZIER A, SCHNEIDER G, 1986,

  HPLC-BASED METHODS FOR THE IDENTIFICATION OF GIBBERELLIN CONJUGATES - METABOLISM OF [H-3] GIBBERELLIN-A4 IN SEEDLINGS OF PHASEOLUS-COCCINEUS

  , PHYTOCHEMISTRY, Vol: 25, Pages: 1823-1828, ISSN: 0031-9422
  • Cite
  • Citations: 26
• Journal article
  FRANKS NP, LIEB WR, 1986,

  THE PHARMACOLOGY OF SIMPLE MOLECULES

  , ARCHIVES OF TOXICOLOGY, Pages: 27-37, ISSN: 0340-5761
  • Author Web Link
  • Cite
  • Citations: 13
• Journal article
  BEVIS PJR, LYNCH C, HILLYARD CJ, AZRIA M, ATTINGER M, MORRIS HR, MACINTYRE Iet al., 1986,

  THE PLASMA-CALCIUM MODULATING EFFECTS OF CALCITONIN GENE-RELATED PEPTIDE

  , BONE, Vol: 7, Pages: 149-149, ISSN: 8756-3282
  • Author Web Link
  • Cite
• Journal article
  Franks NP, Lieb WR, 1986,

  The pharmacology of simple molecules.

  , Arch Toxicol Suppl, Vol: 9, Pages: 27-37, ISSN: 0171-9750

  The biological effects of simple molecules have traditionally been ascribed to their actions on the lipid portions of biological membranes. However, at the low concentrations of these molecules which induce general anaesthesia or have acute toxic effects in animals, changes in lipid bilayer properties are so small that they are unlikely to be relevant biologically. On the other hand, these molecules do inhibit the activity of a pure lipid-free protein, with ED50 concentrations which are essentially identical to the biological ED50 and LD50 concentrations. Moreover, the well-known but puzzling cutoffs in potencies in homologous series of compounds are also found with this enzyme. The accumulating evidence now suggests that the pharmacological effects of low concentrations of relatively inert agents are best explained in terms of their direct binding to amphiphilic pockets of circumscribed dimensions on proteins.

  • Abstract
  • Author Web Link
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• Journal article
  RAWLINGS CJ, TAYLOR WR, NYAKAIRU J, FOX J, STERNBERG MJEet al., 1986,

  USING PROLOG TO REPRESENT AND REASON ABOUT PROTEIN-STRUCTURE

  , LECTURE NOTES IN COMPUTER SCIENCE, Vol: 225, Pages: 536-543, ISSN: 0302-9743
  • Author Web Link
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• Journal article
  BRAIN SD, MACINTYRE I, TIPPINS JR, MORRIS HR, WILLIAMS TJet al., 1986,

  THE VASODILATOR ACTIVITY OF HUMAN ALPHA-CALCITONIN GENE-RELATED PEPTIDE AND RELATED STRUCTURES

  , ACTA PHARMACOLOGICA ET TOXICOLOGICA, Vol: 59, Pages: 147-147, ISSN: 0001-6683
  • Author Web Link
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• Book chapter
  Koufopanou V, 1986,

  The cost of reproduction

  , Oxford Surveys in Evolutionary Biology Vol. 3
  • Cite
• Journal article
  JANSSON PE, LONNGREN J, WIDMALM G, LEONTEIN K, SLETTENGREN K, SVENSON SB, WRANGSELL G, DELL A, TILLER PRet al., 1985,

  STRUCTURAL STUDIES OF THE O-ANTIGEN POLYSACCHARIDES OF KLEBSIELLA O5 AND ESCHERICHIA-COLI O8

  , CARBOHYDRATE RESEARCH, Vol: 145, Pages: 59-66, ISSN: 0008-6215
  • Cite
  • Citations: 88
• Journal article
  BRAIN SD, MACINTYRE I, MORRIS HR, TIPPINS JR, WILLIAMS TJet al., 1985,

  COULD THE POTENT VASODILATOR CALCITONIN GENE-RELATED PEPTIDE BE THE MEDIATOR OF THE FLARE RESPONSE IN HUMAN-SKIN

  , REGULATORY PEPTIDES, Vol: 13, Pages: 92-92, ISSN: 0167-0115
  • Author Web Link
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  • Citations: 1
• Journal article
  Southan C, Thompson E, Panico M, Etienne T, Morris HR, Lane DAet al., 1985,

  Characterization of peptides cleaved by plasmin from the C-terminal polymerization domain of human fibrinogen.

  , J Biol Chem, Vol: 260, Pages: 13095-13101, ISSN: 0021-9258

  The C-terminal region of the fibrinogen gamma chain is known to participate in several functional interactions including fibrin polymerization. This part of the molecule is retained on the gamma chain of fragment D (FgD) when fibrinogen is digested by plasmin in the presence of calcium to produce the fragment D-fragment E (FgD X FgE) complex but is lost if FgD is prepared in the absence of calcium. In an attempt to characterize the C-terminal polymerization domain we have used three techniques to examine this further degradation of FgD following the addition of EDTA and plasmin. Analysis of the digestion by sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed a progressive cleavage of the gamma chain to two small remnants. The polymerization-inhibitory activity of the whole digest was studied using acid-solubilized fibrin. A progressive loss of inhibitory activity was associated with gamma chain shortening, reaching greater than a 120-fold reduction at the end of digestion. The cleavage of peptides was followed by reverse-phase high performance liquid chromatography and the release of a characteristic peptide triplet was associated with gamma chain cleavage. Manual sequencing, amino acid analysis, and fast atom bombardment mass spectrometry established the three peptides as gamma 303-356, 357-373, and 374-405. These peptides have sequences in common with those peptides recently reported by other investigators to be potent polymerization inhibitors. However, when a mixture of the three peptides was added in a 200-fold molar excess to polymerizing fibrin, no inhibitory activity could be demonstrated. It is concluded that the C-terminal polymerization domain of fibrinogen may be an extended region which includes the sequence gamma 303-405, when this is contiguous with the remainder of the gamma chain.

  • Abstract
  • Author Web Link
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