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  • Journal article
    TOBIAS JAY, MERLIS S, 1970,

    LEVODOPA AND SCHIZOPHRENIA

    , JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, Vol: 211, Pages: 1857-&
  • Journal article
    Lucas F, Barber M, Wolstenholme WA, Geddes AJ, Graham GN, Morris HRet al., 1969,

    Mass-spectrometric determination of the amino acid sequences in peptides isolated from the protein silk fibroin of Bombyx mori.

    , Biochem J, Vol: 114, Pages: 695-702, ISSN: 0264-6021

    Several peptides were isolated from the protein silk fibroin of Bombyx mori by means of ion-exchange chromatography of a chymotryptic digest. The sequences of three of the peptides, Gly-Ala-Gly-Tyr, Gly-Val-Gly-Tyr and Gly-Ala-Gly-Ala-Gly-Ala-Gly-Tyr, were known from previous chemical work, but the sequence of the fourth, Gly-Ala-Gly-Val-Gly-Ala-Gly-Tyr, was previously only partially known. The necessary volatility for mass-spectrometric examination of the peptides was achieved by permethylation of the N-acetyl-peptide methyl ester derivatives. From the mass spectra it was possible to confirm the known sequences and to establish that of the partially known one. In one instance it was possible to deduce from the same mass spectrum the sequence of a main peptide component and that of a small amount of contaminating peptide. These results demonstrate for the first time the use of mass spectrometry in the determination of the amino acid sequences in peptides from a protein hydrolysate.
  • Journal article
    Morris HR, Geddes AJ, Graham GN, 1969,

    Some problems associated with the amino acid-sequence analysis of proteins by mass spectrometry.

    , Biochem J, Vol: 111, ISSN: 0264-6021
  • Journal article
    Cohen F, Sternberg M, 1965,

    [Trials with oxyphenbutazone in pediatrics].

    , Ann Pediatr (Paris), Vol: 12, Pages: 391-395, ISSN: 0066-2097
  • Journal article
    HD Williams, RK Poole,

    Reduction of ferric iron by Escherichia coli

    , Society for General Microbiology Quarterly, Vol: 10, Pages: 4-4
  • Thesis dissertation
    Laroche L,

    Phlebovirus, Leishmania and sand flies : interactions and impacts on biology and transmission of these pathogens

    <jats:title>Phlebovirus, Leishmania et phlébotomes : interactions et impacts sur la biologie et la transmission de ces agents pathogènes</jats:title> <jats:p xml:lang="fr">Les phlébotomes, présents dans toutes les régions intertropicales, sont des insectes diptères appartenant à la famille des Psychodidae et à la sous-famille des Phlebotominae. Une centaine d’espèces sont identifiées comme vecteurs dont 40% sont des vecteurs confirmés. Ces espèces sont impliquées dans la transmission de différents agents pathogènes tels que les leishmanies et les Phlebovirus. Les leishmanies sont des protozoaires Kinetoplastidae de la famille des Trypanosomatidae appartenant au genre Leishmania responsables de maladies parasitaires. Elles parasitent un large panel d’hôtes vertébrés, dont l’homme. Par exemple, Leishmania infantum est une espèce qui sévit sur le pourtour méditerranéen et qui peut provoquer des formes viscérales graves en absence de traitement. Les virus du genre Phlebovirus appartiennent à la famille des Phenuiviridae et à l'ordre des Bunyavirales. Certains Phlebovirus sont associés à des pathologies humaines, tel que le virus Toscana (TOSV) présentant une activité neurotrope. Le TOSV et le parasite Le. infantum co-circulent dans le bassin méditerranéen et partagent certaines espèces vectrices, telles que Phlebotomus perniciosus. Des études ont mis en évidence des co-infections chez des hôtes mammifères, mais aucune n'a pu le confirmer chez le phlébotome en population naturelle. Les interactions biologiques entre le TOSV et le phlébotome et entre ces deux agents pathogènes chez l’hôte et le vecteur sont encore méconnues.Dan
  • Journal article
    Xiao Y, Wigneshweraraj SR, Weinzierl R, Wang YP, Buck Met al.,

    Construction and functional analyses of a comprehensive sigma54 site-directed mutant library using alanine-cysteine mutagenesis.

    , Nucleic Acids Res., Vol: 37, Pages: 4482-4497
  • Journal article
    Cámara B, Liu M, Reynolds J, Shadrin A, Liu B, Kwok K, Simpson P, Weinzierl R, Severinov K, Cota E, Matthews S, Wigneshweraraj SRet al.,

    T7 phage protein Gp2 inhibits the Escherichia coli RNA polymerase by antagonizing stable DNA strand separation near the transcription start site.

    , Proc Natl Acad Sci USA, Vol: 107, Pages: 2247-2252
  • Journal article
    Weinzierl RO, Axton JM, Ghysen A, Akam Met al.,

    Ultrabithorax mutations in constant and variable regions of the protein coding sequence.

    , Genes & Dev., Vol: 1, Pages: 386-397
  • Patent
    Collins J, Mann D, Armstrong A, Low Cet al.,

    CDC25 inhibitors

    , GB 1005980.6
  • Conference paper
    Ho KK, Mann DJ,

    The Role of Nuclear PtdIns(4,5)P2 turnover in Mammalian Cell Cycle

    , Gordon Research Conference on Signal Transduction Within the Nucleus
  • Conference paper
    Child ES, Mann DJ,

    Role of the cyclin encoded by human Herpesvirus 8 in the deregulation of the cell cycle

    , UK Molecular Biology and Cancer Network meeting
  • Conference paper
    Mann DJ, Jones NC,

    E2F-1 but not E2F-4 can overcome p16-induced cell cycle arrest.

    , Cold Spring Harbor meeting on The Cell Cycle
  • Conference paper
    Mann DJ, Jones NC,

    Use of cdk-specific inhibitors to analyse the G1/S transition in mammalian cells

    , DNA Tumour Viruses
  • Conference paper
    Mann DJ, Cohen PTW,

    Protein serine/threonine phosphatase V, the D. melanogaster homologue of S. cerevisiae SIT4

    , FASEB meeting on Protein Phosphatases
  • Conference paper
    Mann DJ, Cohen PTW,

    Identification of a novel Drosophila protein phosphatase, PPV

    , EMBO-FEBS meeting on Protein Phosphatases
  • Patent
    Weinzierl RO,

    Chromatin Topology

    , 0116453.2
  • Software
    Gilestro GF, Cirelli C,

    pySolo

    pySolo is a multiplatform software for analysis of sleep and locomotor activity in Drosophila melanogaster. pySolo provides a user-friendly graphic interface and it has been developed with the specific aim of being accessible, portable, fast and easily expandable through an intuitive plug-in structure. Support for development of additional plug-ins is provided through a community website. AVAILABILITY: Software and documentation are located at (http://www.pysolo.net). pySolo is a free software released under the GNU General Public License.
  • Journal article
    TR BMAH,

    Buck and Hoover, An ATPase R-Finger Leaves Its Print on Transcriptional Activation, Structure (2010), doi:10.1016/j.str.2010.10.002
  • Journal article
    Stumpf MHTTXSTTGJCEMBJWPMPH,

    M. Huvet, T. Toni, X. Sheng, T. Thorne, G. Jovanovic, C. Engl, M. Buck, J.W. Pinney, M.P.H. Stumpf. Mapping the evolution of the Phage shock protein (Psp) response system: interplay between protein function, genomic organization and system function, Molecular Biology Evolution (In Press)

    , Molecular Biology Evolution (In Press)
  • Journal article
    Aukauloo A, Leibl W, Rutherford AW,

    Water photolysis by molecular biomimetics

    , ACTUALITE CHIMIQUE, Pages: 42-49, ISSN: 0151-9093
  • Journal article
    Pitelka LF, Gardner RH, Ash J, Berry S, Gitay H, Noble IR, Saunders A, Bradshaw RHW, Brubaker L, Clark JS, Davis MB, Sugita S, Dyer JM, Hengeveld R, Hope G, Huntley B, King GA, Lavorel S, Mack RN, Malanson GP, McGlone M, Prentice IC, Rejmanek Met al.,

    Plant migration and climate change (vol 85, pg 464, 1997)

    , AMERICAN SCIENTIST, Vol: 85, Pages: 501-501, ISSN: 0003-0996
  • Journal article
    Pitelka LF, Gardner RH, Ash J, Berry S, Gitay H, Noble IR, Saunders A, Bradshaw RHW, Brubaker L, Clark JS, Davis MB, Sugita S, Dyer JM, Hengeveld R, Hope G, Huntley B, King GA, Lavorel S, Mack RN, Malanson GP, McGlone M, Prentice IC, Rejmanek Met al.,

    Plant migration and climate change

    , AMERICAN SCIENTIST, Vol: 85, Pages: 464-473, ISSN: 0003-0996
  • Book chapter
    Song J, mermaz B, Liu F,

    RNA ImmunoPrecipitation protocol to identify protein-RNA interaction in Arabidopsis thaliana
  • Journal article
    Maitner BS, Pearse W, Roehrdanz P, Enquist BJ, Sanderson MJet al.,

    APPENDIX C. Re-scaling phylogenetic branches to reflect trait evolution

    , THE UNIVERSITY OF ARIZONA GRADUATE COLLEGE, Vol: 1001, Pages: 86-86
  • Book
    Panossian B,

    Genome profiling of vancomycin-resistant enterococcal clinical Isolates from Lebanon
  • Thesis dissertation
    Chen S-Y,

    On subannual variability in the abyssal ocean

    <jats:p>The abyssal ocean is a critical yet understudied component of the climate system and is of growing economic interest. This thesis combines field observations and numerical modeling to advance our understanding of subannual variability in the abyssal ocean and its broader implications. First, hydrographic measurements from the Clarion-Clipperton Zone of the tropical eastern North Pacific are used to characterize the structure and variability of the bottom mixed layer (BML) in a region targeted for deep-sea mining. The observations reveal a spatially and temporally variable BML with a mean thickness of ∼250m and influenced by interactions with mesoscale eddies and abyssal thermal fronts. A simplified model of sediment transport suggests that such variations in BML structure could significantly influence the dispersal of sediments resuspended by seabed mining activities. Second, idealized model experiments are conducted to explore the genesis of benthic storms – episodes of strong near-bottom flows and sediment entrainment – underneath an unstable, surface-intensified jet resembling the Gulf Stream east of Cape Hatteras. In these experiments, the baroclinic instability of the jet gives rise to deep cyclonic and anticyclonic eddies through eddy barotropization and produces high levels of eddy kinetic energy at abyssal depths through the convergence of vertical eddy pressure fluxes. The near-bottom currents are comparable in magnitude to those observed during benthic storms, with vertical shears strong enough to produce BMLs up to 𝒪(100)m thick. Deep cyclonic eddies transport particles from near the bottom over the entire BML and could contribute to benthic nepheloid layers. The results suggest that the abyssal response to the intrinsic instability of surface-intensified currents could contribute significantly to subannual variability near the seafloor. Third, a model simulation of western North Atlantic circulation is performed to study th
  • Journal article
    Majumdar A, Upadhyay MK, Giri B, Karwadiya J, Bose S, Jaiswal MKet al.,

    Iron Oxide Doped Rice Biochar Reduces Soil-Plant Arsenic Stress, Improves Nutrient Values: An Amendment Towards Sustainable Development Goals

    , SSRN Electronic Journal
  • Thesis dissertation
    Yen P-S,

    Transgenic mosquitoes for controlling transmission of arboviruses

    <jats:title>Moustiques transgéniques pour contrôler la transmission des arbovirus</jats:title> <jats:p xml:lang="fr">Les arbovirus (virus transmis par des arthropodes) sont à l'origine de maladies humaines telles que la dengue, le chikungunya ou encore le Zika. Le moustique Aedes aegypti, est le vecteur majeur de ces trois arbovirus. La faible efficacité des méthodes de contrôle des populations de moustiques, principalement réalisées au moyen d'insecticides chimiques ouvre un champ de développement de nouvelles approches en lutte antivectorielle. Le moustique, hôte vecteur, contrôle la réplication virale en limitant les réponses immunitaires antivirales. La machinerie RNA interférence (RNAi) est la voie jouant un rôle majeur dans l'immunité antivirale chez le moustique. Alors que le rôle des deux voies, siRNA (" small interfering RNA ") et piRNA (" piwi-interfering RNA "), est de mieux en mieux compris dans les réactions antivirales du vecteur, peu de connaissances sont disponibles à ce jour en ce qui concernent les interactions entre la voie miRNA (" micro RNA ") et les arbovirus. Ainsi, nous proposons une analyse détaillée des mécanismes par lesquels les miARN tentent de réguler la réplication virale chez le moustique. Dans la première partie de la thèse, nous avons effectué une analyse génomique pour identifier les miRNAs pouvant interagir chez Ae. aegypti avec divers lignées/génotypes des virus chikungunya (CHIKV), de dengue (DENV) et de Zika. Avec l'aide d'outils de prédiction faisant appel à divers algorithmes, plusieurs sites de liaison de miARN avec différents lignées/génotypes de chaque arbovirus ont été identifiés. Nous avons ens
  • Journal article
    DAVIS KR, DARVILL AG, ALBERSHEIM P, DELL Aet al.,

    HOST-PATHOGEN INTERACTIONS .30. CHARACTERIZATION OF ELICITORS OF PHYTOALEXIN ACCUMULATION IN SOYBEAN RELEASED FROM SOYBEAN CELL-WALLS BY ENDOPOLYGALACTURONIC ACID LYASE

    , ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, Vol: 41, Pages: 39-48, ISSN: 0939-5075
    • Cite
    • Citations: 44

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