In this section
@article{Allen:2025:10.1002/smll.202411220,
author = {Allen, ME and Sun, Y and Chan, CL and Paez-Perez, M and Ces, O and Elani, Y and Contini, C},
doi = {10.1002/smll.202411220},
journal = {Small},
title = {Thermally Driven Dynamic Behaviors in Polymeric Vesicles.},
url = {http://dx.doi.org/10.1002/smll.202411220},
year = {2025}
}
TY - JOUR
AB - Stimuli-responsive polymeric vesicles offer a versatile platform for mimicking dynamic cell-like behaviors for synthetic cell applications. In this study, thermally responsive polymeric droplets derived from poly(ethylene oxide)-poly(butylene oxide) (PEO-PBO) polymersomes, aiming to create synthetic cell models that mimic key biological functions are developed. Upon heating, the nanoscale vesicles undergo fusion, transforming into sponge-like microscale droplets enriched with membrane features. By modulating the temperature, these droplets display dynamic properties such as contractility, temperature-induced fusion, and cargo trapping, including small molecules and bacteria, thereby demonstrating their ability to dynamically interface with biological entities. The findings demonstrate the potential of our sponge-like droplets in synthetic cell applications, contributing to the understanding of PEO-PBO polymersomes' unique characteristics, expanding the capabilities of synthetic cell structures, and representing an exciting possibility for advancing soft matter engineering to cell-like behaviors.
AU - Allen,ME
AU - Sun,Y
AU - Chan,CL
AU - Paez-Perez,M
AU - Ces,O
AU - Elani,Y
AU - Contini,C
DO - 10.1002/smll.202411220
PY - 2025///
TI - Thermally Driven Dynamic Behaviors in Polymeric Vesicles.
T2 - Small
UR - http://dx.doi.org/10.1002/smll.202411220
UR - https://www.ncbi.nlm.nih.gov/pubmed/40042428
ER -
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