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• Conference paper
  Casey D, Wylie D, Gallo J, Dent M, Salehi-Reyhani A, Wilson R, Brooks N, Long N, Willison K, Klug D, Neil M, Neale S, Cooper J, Ces Oet al., 2015,

  A novel, all-optical tool for controllable and non-destructive poration of cells with single-micron resolution

  , Bio-Optics: Design and Application 2015, Publisher: Optical Society of America

  We demonstrate controllable poration within ≈1 µm regions of individual cells, mediated by a near-IR laser interacting with thin-layer amorphous silicon substrates. This technique will allow new experiments in single-cell biology, particularly in neuroscience.

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• Journal article
  Duerrbeck A, Gorelik S, Hobley J, Yong AM, Subramanian GS, Hor A, Long Net al., 2015,

  New solid-state Eu(III)-containing metallo-supramolecular polymers: morphology control and optical wave-guiding properties

  , JOURNAL OF MATERIALS CHEMISTRY C, Vol: 3, Pages: 8992-9002, ISSN: 2050-7526
  • Author Web Link
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  • Citations: 14
• Book chapter
  Gallo J, Long NJ, 2015,

  NANOPARTICULATE MRI CONTRAST AGENTS

  , CHEMISTRY OF MOLECULAR IMAGING, Editors: Long, Wong, Publisher: JOHN WILEY & SONS INC, Pages: 199-224, ISBN: 978-1-118-09327-6
  • Author Web Link
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  • Citations: 1
• Book chapter
  Long NJ, Wong W-T, 2015,

  PREFACE

  , Chemistry of Molecular Imaging, Editors: Long, Wong, Publisher: JOHN WILEY & SONS INC, Pages: IX-U9, ISBN: 978-1-118-09327-6
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• Journal article
  Inkpen MS, White AJP, Albrecht T, Long NJet al., 2014,

  Avoiding problem reactions at the ferrocenyl-alkyne motif: a convenient synthesis of model, redox-active complexes for molecular electronics

  , DALTON TRANSACTIONS, Vol: 43, Pages: 15287-15290, ISSN: 1477-9226
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• Journal article
  Hurtubise VL, McArdle JM, Naeem S, Toscani A, White AJP, Long NJ, Wilton-Ely JDETet al., 2014,

  Multimetallic Complexes and Functionalized Nanoparticles Based on Unsymmetrical Dithiocarbamate Ligands with Allyl and Propargyl Functionality

  , INORGANIC CHEMISTRY, Vol: 53, Pages: 11740-11748, ISSN: 0020-1669
  • Author Web Link
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  • Citations: 20
• Journal article
  Haslop A, Wells L, Gee A, Plisson C, Long Net al., 2014,

  One-Pot Multi-Tracer Synthesis of Novel <SUP>18</SUP>F-Labeled PET Imaging Agents

  , MOLECULAR PHARMACEUTICS, Vol: 11, Pages: 3818-3822, ISSN: 1543-8384
  • Author Web Link
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  • Citations: 27
• Journal article
  Gallo J, Kamaly N, Lavdas I, Stevens E, Nguyen Q, Wylezinska-Arridge M, Aboagye EO, Long NJet al., 2014,

  CXCR4-targeted and MMP-responsive iron oxide nanoparticles for enhanced magnetic resonance imaging

  , Angewandte Chemie International Edition, Vol: 53, Pages: 9550-9554, ISSN: 1521-3773

  MRI offers high spatial resolution with excellent tissue penetration but it has limited sensitivity and the commonly administered contrast agents lack specificity. In this study, two sets of iron oxide nanoparticles (IONPs) were synthesized that were designed to selectively undergo copper-free click conjugation upon sensing of matrix metalloproteinase (MMP) enzymes, thereby leading to a self-assembled superparamagnetic nanocluster network with T2 signal enhancement properties. For this purpose, IONPs with bioorthogonal azide and alkyne surfaces masked by polyethylene glycol (PEG) layers tethered to CXCR4-targeted peptide ligands were synthesized and characterized. The IONPs were tested in vitro and T2 signal enhancements of around 160 % were measured when the IONPs were incubated with cells expressing MMP2/9 and CXCR4. Simultaneous systemic administration of the bioorthogonal IONPs in tumor-bearing mice demonstrated the signal-enhancing ability of these ‘smart’ self-assembling nanomaterials.

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• Conference paper
  Williams CK, Bakewell C, Long N, Auffrant Aet al., 2014,

  Stereoblock polylactide: New, highly active, and iso-selective catalysts based on group 3/lanthanide phosphasalen complexes

  , 248th National Meeting of the American-Chemical-Society (ACS), Publisher: AMER CHEMICAL SOC, ISSN: 0065-7727
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• Journal article
  Bakewell C, White AJP, Long NJ, Williams CKet al., 2014,

  Metal-Size Influence in Iso-Selective Lactide Polymerization

  , Angewandte Chemie-International Edition, Vol: 53, Pages: 9226-9230, ISSN: 1521-3773

  Iso-selective initiators for the ring-opening polymerization (ROP) of rac-lactide are rare outside of Group 13. We describe the first examples of highly iso-selective lutetium initiators. The phosphasalen lutetium ethoxide complex shows excellent iso-selectivity, with a Pi value of 0.81–0.84 at 298 K, excellent rates, and high degrees of polymerization control. Conversely, the corresponding La derivative exhibits moderate heteroselectivity (Ps=0.74, 298 K). Thus, the choice of metal center is shown to be crucial in determining the level and mode of stereocontrol. The relative order of rates for the series of complexes is inversely related to metallic covalent radius: that is, La>Y>Lu.

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• Conference paper
  Wells L, Haslop A, Coello C, Keat N, Gee A, Passchier J, Long N, Plisson Cet al., 2014,

  Evaluation of novel phosphonium cations as imaging agents for changes in mitochondrial membrane potential

  , Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging (SNMMI), Publisher: SOC NUCLEAR MEDICINE INC, ISSN: 0161-5505
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  • Citations: 3
• Journal article
  Phanopoulos A, Brown NJ, White AJP, Long NJ, Miler PWet al., 2014,

  Synthesis, Characterization, and Reactivity of Ruthenium Hydride Complexes of N-Centered Triphosphine Ligands

  , INORGANIC CHEMISTRY, Vol: 53, Pages: 3742-3752, ISSN: 0020-1669
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  • Citations: 33
• Conference paper
  Genicio N, Gallo J, Dziasko M, Long NJ, Shortt AJet al., 2014,

  Biofunctionalized heavy metal free quantum dots (QD) as a tool for tracking transplanted limbal epithelial cells

  , Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404
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• Journal article
  Kealey S, White AJP, Gee AD, Long NJet al., 2014,

  Evaluation of [<SUP>12</SUP>C/<SUP>11</SUP>C] Carbon Monoxide Binding to Copper( I) Tris( pyrazolyl) borate Complexes

  , EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Vol: 2014, Pages: 1896-1905, ISSN: 1434-1948
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  • Citations: 12
• Journal article
  Ghani SFA, Wright M, Paramo JG, Bottrill M, Green M, Long N, Thanou Met al., 2014,

  Three bisphosphonate ligands improve the water solubility of quantum dots

  , FARADAY DISCUSSIONS, Vol: 175, Pages: 153-169, ISSN: 1359-6640
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  • Citations: 5

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