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  • Conference paper
    Stasiuk GJ, Minuzzi F, Sae-Heng M, Long NJ, Rutter GAet al., 2013,

    Dual modal MR/fluorescent zinc sensing probes for in vivo beta cell imaging

    , 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Publisher: SPRINGER, Pages: S211-S211, ISSN: 0012-186X
  • Journal article
    Haslop A, Wells L, Murphy P, Gee A, Long N, Plisson Cet al., 2013,

    Novel <SUP>18</SUP>F-labelled phosphonium cations as imaging agents of the mitochondrial membrane potential during apoptosis

    , JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Vol: 56, Pages: S143-S143, ISSN: 0362-4803
  • Journal article
    Haslop A, Gee A, Plisson C, Long Net al., 2013,

    Fully automated radiosynthesis of [1-(2-[18F]fluoroethyl),1H[1,2,3]triazole 4-ethylene] triphenylphosphonium bromide as a potential positron emission tomography tracer for imaging apoptosis

    , JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Vol: 56, Pages: 313-316, ISSN: 0362-4803
  • Conference paper
    Bakewell CM, Thi-Phuong-Anh C, Haaf M, Williams CK, Long NJ, Auffrant A, Platel RHet al., 2013,

    <i>Bis</i>(quinolinolato)aluminium ethyl and yttrium phosphasalen complexes: New <i>iso</i>-selective initiators for <i>rac</i>-lactide ring-opening polymerisation

    , Symposium on Physicochemical Characterization of Organic Matter - Past, Present, Future, and Role of Environment / 245th National Spring Meeting of the American-Chemical-Society (ACS), Publisher: AMER CHEMICAL SOC, ISSN: 0065-7727
  • Journal article
    Bakewell C, Thi-Phuong-Anh C, Le Goff XF, Long NJ, Auffrant A, Williams CKet al., 2013,

    Yttrium Phosphasalen Initiators for <i>rac</i>-Lactide Polymerization

    , ORGANOMETALLICS, Vol: 32, Pages: 1475-1483, ISSN: 0276-7333
    • Cite
    • Citations: 59
  • Journal article
    Inkpen MS, White AJP, Albrecht T, Long NJet al., 2013,

    Rapid Sonogashira cross-coupling of iodoferrocenes and the unexpected cyclo-oligomerization of 4-ethynylphenylthioacetate

    , Chem. Commun.
  • Journal article
    Stasiuk GJ, Long NJ, 2013,

    The ubiquitous DOTA and its derivatives: the impact of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid on biomedical imaging

    , CHEMICAL COMMUNICATIONS, Vol: 49, Pages: 2732-2746, ISSN: 1359-7345
  • Journal article
    Tietz O, Kamaly N, Smith G, Shamsaei E, Bhakoo KK, Long NJ, Aboagye EOet al., 2013,

    Design, synthesis and in vitro characterization of fluorescent and paramagnetic CXCR4-targeted imaging agents.

    , Am J Nucl Med Mol Imaging, Vol: 3, Pages: 372-383, ISSN: 2160-8407

    The G-protein coupled C-X-C chemokine receptor type 4 (CXCR4) is highly overexpressed in a range of cancers and is therefore an excellent biomarker for cancer imaging. To this end targeted iron oxide nanoparticles were developed and utilised for in vitro imaging of MDA-MB-231 breast cancer cells overexpressing the CXCR4 receptor. Nanoparticles comprising an iron oxide core, encapsulated in a stabilising epichlorohydrin crossed-linked dextran polymer, were conjugated to a cyclopentapeptide with affinity to the CXCR4 receptor. The particles were characterized for their size, surface charge and r2 relaxivity at 4.7 T. MR imaging of the CXCR4 receptor with targeted iron oxide nanoparticles revealed an approximately 3-fold increase in T2 signal enhancement of MDA-MB-231 cells compared to non-targeted controls. Prussian blue staining of labeled MDA-MB-231 cells revealed darker and more intense staining of the cellular membrane. This study demonstrates the potential of targeted iron oxide nanoparticles for the imaging of the CXCR4 receptor by magnetic resonance imaging (MRI).
  • Journal article
    Inkpen MS, Du S, Driver M, Albrecht T, Long NJet al., 2013,

    Oxidative purification of halogenated ferrocenes

    , Dalton Transactions, Vol: 42, Pages: 2813-2816
  • Journal article
    Gallo J, Long NJ, Aboagye EO, 2013,

    Magnetic nanoparticles as contrast agents in the diagnosis and treatment of cancer

    , CHEMICAL SOCIETY REVIEWS, Vol: 42, Pages: 7816-7833, ISSN: 0306-0012
    • Cite
    • Citations: 202
  • Journal article
    Inkpen MS, Albrecht T, Long NJ, 2013,

    Branched Redox-Active Complexes for the Study of Novel Charge Transport Processes

    , Organometallics, Vol: 32, Pages: 6053-6060
  • Journal article
    Stasiuk GJ, Smith H, Wylezinska-Arridge M, Tremoleda JL, Trigg W, Luthra SK, Iveson VM, Gavins FNE, Long NJet al., 2013,

    Gd<SUP>3+</SUP> cFLFLFK conjugate for MRI: a targeted contrast agent for FPR1 in inflammation

    , CHEMICAL COMMUNICATIONS, Vol: 49, Pages: 564-566, ISSN: 1359-7345
    • Cite
    • Citations: 30
  • Journal article
    Bakewell C, Thi-Phuong-Anh C, Long N, Le Goff XF, Auffrant A, Williams CKet al., 2012,

    Yttrium Phosphasalen Initiators for <i>rac</i>-Lactide Polymerization: Excellent Rates and High Iso-Selectivities

    , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 134, Pages: 20577-20580, ISSN: 0002-7863
    • Cite
    • Citations: 206
  • Journal article
    Stasiuk GJ, Faulkner S, Long NJ, 2012,

    Novel imaging chelates for drug discovery

    , CURRENT OPINION IN PHARMACOLOGY, Vol: 12, Pages: 576-582, ISSN: 1471-4892
  • Journal article
    Tate CW, Gee AD, Vilar R, White AJP, Long NJet al., 2012,

    Reversible carbon monoxide binding at copper(I) P-S-X (<i>X</i>=N, O) coordination polymers

    , JOURNAL OF ORGANOMETALLIC CHEMISTRY, Vol: 715, Pages: 39-42, ISSN: 0022-328X

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Professor Nick Long
Email: n.long@imperial.ac.uk
Telephone: +44 (0)20 7594 5781

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