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• Journal article
  Baggaley RF, Boily MC, White RG, Alary Met al., 2006,

  Risk of HIV-1 transmission for parenteral exposure and blood transfusion: a systematic review and meta-analysis

  , AIDS, Vol: 20, Pages: 805-812, ISSN: 0269-9370
  • Cite
  • Citations: 147
• Journal article
  Garnett GP, Garcia-Calleja JM, Rehle T, Gregson Set al., 2006,

  Behavioural data as an adjunct to HIV surveillance data

  , SEXUALLY TRANSMITTED INFECTIONS, Vol: 82, Pages: I57-I62, ISSN: 1368-4973
  • Author Web Link
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  • Citations: 25
• Journal article
  A Mahomva, S Greby, S Dube, 2006,

  HIV prevalence and trends from data in Zimbabwe, 1997–2004

  , Vol: 82
  • Author Web Link
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• Journal article
  Griffin JT, Fraser C, Gras L, de Wolf F, Ghani ACet al., 2006,

  The effect on treatment comparisons of different measurement frequencies in human immunodeficiency virus observational databases

  , AMERICAN JOURNAL OF EPIDEMIOLOGY, Vol: 163, Pages: 676-683, ISSN: 0002-9262
  • Author Web Link
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  • Citations: 11
• Journal article
  Hallett TB, Aberle-Grasse J, Boulos LM, Cayemittes MPA, Cheluget B, Chipeta J, Dorrington R, Dube S, Ekra AK, Garcia-Calleja JM, Garnett GP, Greby S, Gregson S, Grove JT, Hader S, Hanson J, Hladik W, Ismail S, Kassim S, Kirungi W, Kouassi L, Mahomva A, Marum L, Maurice C, Nolan M, Rehle T, Stover J, Walker Net al., 2006,

  Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti

  , SEXUALLY TRANSMITTED INFECTIONS, Vol: 82, Pages: I1-I8, ISSN: 1368-4973
  • Cite
  • Citations: 81
• Journal article
  Garnett GP, Gregson S, Stanecki KA, 2006,

  Criteria for detecting and understanding changes in the risk of HIV infection at a national level in generalised epidemics

  , SEXUALLY TRANSMITTED INFECTIONS, Vol: 82, Pages: I48-I51, ISSN: 1368-4973
  • Author Web Link
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  • Citations: 21
• Journal article
  Vlahov D, Celentano DD, 2006,

  Access to highly active antiretroviral therapy for injection drug users: adherence, resistance, and death.

  , Cad Saude Publica, Vol: 22, Pages: 705-718, ISSN: 0102-311X

  Injection drug users (IDUs) continue to comprise a major risk group for HIV infection throughout the world and represent the focal population for HIV epidemics in Asia and Eastern Europe/Russia. HIV prevention programs have ranged from HIV testing and counseling, education, behavioral and network interventions, drug abuse treatment, bleach disinfection of needles, needle exchange and expanded syringe access, as well as reducing transition to injection and primary substance abuse prevention. With the advent of highly active antiretroviral therapy (HAART) in 1996, dramatic clinical improvements have been seen. In addition, the treatment's impact on reducing HIV viral load (and therefore transmission by all routes) provides a stronger rationale for an expansion of the focus on prevention to emphasize early identification and treatment of HIV infected individuals. However, treatment of IDUs has many challenges including adherence, resistance and relapse to high risk behaviors, all of which impact issues of access and ultimately effectiveness of potent antiretroviral treatment. A major current challenge in addressing the HIV epidemic revolves around an appropriate approach to HIV treatment for IDUs.

  • Abstract
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• Journal article
  Hagenaars TJ, Donnelly CA, Ferguson NM, 2006,

  Epidemiological analysis of data for scrapie in Great Britain

  , EPIDEMIOLOGY AND INFECTION, Vol: 134, Pages: 359-367, ISSN: 0950-2688
  • Author Web Link
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  • Citations: 12
• Journal article
  Baggaley RF, Garnett GP, Ferguson NM, 2006,

  Modelling the impact of antiretroviral use in resource-poor settings

  , PLOS MEDICINE, Vol: 3, Pages: 493-504, ISSN: 1549-1277
  • Author Web Link
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  • Citations: 127
• Journal article
  Zody MC, Garber M, Sharpe T, Young SK, Rowen L, O'Neill K, Whittaker CA, Kamal M, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Kodira CD, Madan A, Qin S, Yang X, Abbasi N, Abouelleil A, Arachchi HM, Baradarani L, Birditt B, Bloom S, Bloom T, Borowsky ML, Burke J, Butler J, Cook A, DeArellano K, DeCaprio D, Dorris L, Dors M, Eichler EE, Engels R, Fahey J, Fleetwood P, Friedman C, Gearin G, Hall JL, Hensley G, Johnson E, Jones C, Kamat A, Kaur A, Locke DP, Madan A, Munson G, Jaffe DB, Lui A, Macdonald P, Mauceli E, Naylor JW, Nesbitt R, Nicol R, O'Leary SB, Ratcliffe A, Rounsley S, She X, Sneddon KMB, Stewart S, Sougnez C, Stone SM, Topham K, Vincent D, Wang S, Zimmer AR, Birren BW, Hood L, Lander ES, Nusbaum Cet al., 2006,

  Analysis of the DNA sequence and duplication history of human chromosome 15.

  , Nature, Vol: 440, Pages: 671-675

  Here we present a finished sequence of human chromosome 15, together with a high-quality gene catalogue. As chromosome 15 is one of seven human chromosomes with a high rate of segmental duplication, we have carried out a detailed analysis of the duplication structure of the chromosome. Segmental duplications in chromosome 15 are largely clustered in two regions, on proximal and distal 15q; the proximal region is notable because recombination among the segmental duplications can result in deletions causing Prader-Willi and Angelman syndromes. Sequence analysis shows that the proximal and distal regions of 15q share extensive ancient similarity. Using a simple approach, we have been able to reconstruct many of the events by which the current duplication structure arose. We find that most of the intrachromosomal duplications seem to share a common ancestry. Finally, we demonstrate that some remaining gaps in the genome sequence are probably due to structural polymorphisms between haplotypes; this may explain a significant fraction of the gaps remaining in the human genome.

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