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  • Journal article
    Tarafder MR, Balolong E, Carabin H, Bélisle P, Tallo V, Joseph L, Alday P, Gonzales RON, Riley S, Olveda R, McGarvey STet al., 2005,

    A cross-sectional study of the prevalence of intensity of infection with Schistosoma japonicum in 50 irrigated and rain-fed villages in Samar Province, the Philippines

    , BMC public health, Vol: 6, Pages: 61-61
  • Journal article
    Trotter C, Samuelsson S, Perrocheau A, de Greeff S, de Melker H, Heuberger S, Ramsay Met al., 2005,

    Ascertainment of meningococcal disease in Europe.

    , Euro Surveill, Vol: 10, Pages: 247-250

    Meningococcal disease surveillance in most countries is based upon a combination of statutory notification systems and laboratory reporting, both of which are recognised to underestimate the true burden of disease. The incidence of meningococcal disease varies throughout Europe, and although there are many reasons for this, it is important to quantify the degree of under-ascertainment in order to validate international comparisons. Here, we review the literature on the ascertainment of meningococcal disease in Europe and the available methods for estimating the degree of under-reporting. We found that the sensitivity of surveillance varies between countries and over time, with estimates ranging from 40% to 96%. We identified five methods suitable for conducting ascertainment studies, from simple comparative studies to more complicated capture-recapture and regression analyses. Studies of ascertainment may be used to identify weaknesses and biases in surveillance data, and facilitate the improvement of these systems. These findings are relevant to the surveillance of other infectious diseases, particularly those with lower mortality and a lower public profile than meningococcal disease, for which ascertainment may be worse.

  • Journal article
    Pitman RJ, Cooper BS, Trotter CL, Gay NJ, Edmunds WJet al., 2005,

    Entry screening for severe acute respiratory syndrome (SARS) or influenza: policy evaluation

    , BRITISH MEDICAL JOURNAL, Vol: 331, Pages: 1242-1243, ISSN: 0959-8146
  • Journal article
    Filipe JAN, Boussinesq M, Renz A, Collins RC, Vivas-Martinez S, Grillet ME, Little MP, Basáñez MGet al., 2005,

    Human infection patterns and heterogeneous exposure in river blindness

    , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 102, Pages: 15265-15270, ISSN: 0027-8424
  • Journal article
    Blower S, 2005,

    Modeling the potential public health impact of imperfect HIV vaccines

    , JOURNAL OF INFECTIOUS DISEASES, Vol: 192, Pages: 1494-1495, ISSN: 0022-1899
  • Journal article
    van Sighem A, Danner S, Ghani AC, Gras L, Anderson RM, de Wolf Fet al., 2005,

    Mortality in patients with successful initial response to highly active antiretroviral therapy is still higher than in non-HIV-Infected individuals

    , JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Vol: 40, Pages: 212-218, ISSN: 1525-4135
  • Journal article
    Gregson S, Nyamukapa CA, Garnett GP, Wambe M, Lewis JJC, Mason PR, Chandiwana SK, Anderson RMet al., 2005,

    HIV infection and reproductive health in teenage women orphaned and made vulnerable by AIDS in Zimbabwe

    , AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, Vol: 17, Pages: 785-794, ISSN: 0954-0121
  • Journal article
    Woodroffe R, Donnelly CA, Johnston WT, Bourne FJ, Cheeseman CL, Clifton-Hadley RS, Cox DR, Gettinby G, Hewinson RG, Le Fevre AM, McInerney JP, Morrison WIet al., 2005,

    Spatial association of <i>Mycobacterium bovis</i> infection in cattle and badgers <i>Meles meles</i>

    , JOURNAL OF APPLIED ECOLOGY, Vol: 42, Pages: 852-862, ISSN: 0021-8901
  • Journal article
    Nusbaum C, Zody MC, Borowsky ML, Kamal M, Kodira CD, Taylor TD, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Abouelleil A, Allen NR, Anderson S, Bloom T, Bugalter B, Butler J, Cook A, DeCaprio D, Engels R, Garber M, Gnirke A, Hafez N, Hall JL, Norman CH, Itoh T, Jaffe DB, Kuroki Y, Lehoczky J, Lui A, Macdonald P, Mauceli E, Mikkelsen TS, Naylor JW, Nicol R, Nguyen C, Noguchi H, O'Leary SB, O'Neill K, Piqani B, Smith CL, Talamas JA, Topham K, Totoki Y, Toyoda A, Wain HM, Young SK, Zeng Q, Zimmer AR, Fujiyama A, Hattori M, Birren BW, Sakaki Y, Lander ESet al., 2005,

    DNA sequence and analysis of human chromosome 18.

    , Nature, Vol: 437, Pages: 551-555

    Chromosome 18 appears to have the lowest gene density of any human chromosome and is one of only three chromosomes for which trisomic individuals survive to term. There are also a number of genetic disorders stemming from chromosome 18 trisomy and aneuploidy. Here we report the finished sequence and gene annotation of human chromosome 18, which will allow a better understanding of the normal and disease biology of this chromosome. Despite the low density of protein-coding genes on chromosome 18, we find that the proportion of non-protein-coding sequences evolutionarily conserved among mammals is close to the genome-wide average. Extending this analysis to the entire human genome, we find that the density of conserved non-protein-coding sequences is largely uncorrelated with gene density. This has important implications for the nature and roles of non-protein-coding sequence elements.

  • Journal article
    Ferguson NM, Donnelly CA, Hooper J, Ghani AC, Fraser C, Bartley LM, Rode RA, Vernazza P, Lapins D, Mayer SL, Anderson RMet al., 2005,

    Adherence to antiretroviral therapy and its impact on clinical outcome in HIV-infected patients

    , JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 2, Pages: 349-363, ISSN: 1742-5689

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