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• Journal article
  Gregson S, Adamson S, Papaya S, Mundondo J, Nyamukapa CA, Mason PR, Garnett GP, Chandiwana SK, Foster G, Anderson RMet al., 2007,

  Impact and Process Evaluation of Integrated Community and Clinic-Based HIV-1 Control: A Cluster-Randomised Trial in Eastern Zimbabwe

  , PLOS Medicine, Vol: 4, Pages: 545-555, ISSN: 1549-1277

  BackgroundHIV-1 control in sub-Saharan Africa requires cost-effective and sustainable programmes that promote behaviour change and reduce cofactor sexually transmitted infections (STIs) at the population and individual levels.Methods and FindingsWe measured the feasibility of community-based peer education, free condom distribution, income-generating projects, and clinic-based STI treatment and counselling services and evaluated their impact on the incidence of HIV-1 measured over a 3-y period in a cluster-randomised controlled trial in eastern Zimbabwe. Analysis of primary outcomes was on an intention-to-treat basis. The income-generating projects proved impossible to implement in the prevailing economic climate. Despite greater programme activity and knowledge in the intervention communities, the incidence rate ratio of HIV-1 was 1.27 (95% confidence interval [CI] 0.92–1.75) compared to the control communities. No evidence was found for reduced incidence of self-reported STI symptoms or high-risk sexual behaviour in the intervention communities. Males who attended programme meetings had lower HIV-1 incidence (incidence rate ratio 0.48, 95% CI 0.24–0.98), and fewer men who attended programme meetings reported unprotected sex with casual partners (odds ratio 0.45, 95% CI 0.28–0.75). More male STI patients in the intervention communities reported cessation of symptoms (odds ratio 2.49, 95% CI 1.21–5.12).ConclusionsIntegrated peer education, condom distribution, and syndromic STI management did not reduce population-level HIV-1 incidence in a declining epidemic, despite reducing HIV-1 incidence in the immediate male target group. Our results highlight the need to assess the community-level impact of interventions that are effective amongst targeted population sub-groups.

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• Journal article
  Phuc HK, Andreasen MH, Burton RS, Vass C, Epton MJ, Pape G, Fu G, Condon KC, Scaife S, Donnelly CA, Coleman PG, White-Cooper H, Alphey Let al., 2007,

  Late-acting dominant lethal genetic systems and mosquito control

  , BMC Biology, Vol: 5, ISSN: 1741-7007
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• Conference paper
  Hardell L, Walker MJ, Walhjalt B, Friedman LS, Richter EDet al., 2007,

  Secret ties to industry and conflicting interests in cancer research

  , International Conference on Ethical Considerations and Future Challenges in Occupational and Enviromental Health, Publisher: WILEY, Pages: 227-233, ISSN: 0271-3586
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  • Citations: 52
• Journal article
  Basanez M-G, Razali K, Renz A, Kelly Det al., 2007,

  Density-dependent host choice by disease vectors:: epidemiological implications of the ideal free distribution

  , TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, Vol: 101, Pages: 256-269, ISSN: 0035-9203
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  • Citations: 22
• Journal article
  Hallett TB, Lewis JJC, Lopman BA, Nyamukapa CA, Mushati P, Wambe M, Garnett GP, Gregson Set al., 2007,

  Age at first sex and HIV infection in rural Zimbabwe

  , STUDIES IN FAMILY PLANNING, Vol: 38, Pages: 1-10, ISSN: 0039-3665
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  • Citations: 61
• Journal article
  Kwok KO, Leung GM, Lam WY, Riley Set al., 2007,

  Using models to identify routes of nosocomial infection: a large hospital outbreak of SARS in Hong Kong.

  , Proc Biol Sci, Vol: 274, Pages: 611-617
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• Conference paper
  Cauchemez S, Ferguson NM, 2007,

  The role of mathematical modelling in pandemic preparedness

  , 17th European Congress of Clinical Microbiology and Infectious Diseases/25th International Congress of Chemotherapy, Publisher: ELSEVIER SCIENCE BV, Pages: S16-S16, ISSN: 0924-8579
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• Journal article
  Clarke PS, Ghani AC, 2007,

  A note on parameter estimation for variant Creutzfeldt-Jakob disease epidemic models

  , STATISTICS IN MEDICINE, Vol: 26, Pages: 546-552, ISSN: 0277-6715
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  • Citations: 1
• Journal article
  Gregson S, Mushati P, Nyamukapa C, 2007,

  Adult mortality and erosion of household viability in AIDS-afflicted towns, estates, and villages in eastern Zimbabwe

  , JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Vol: 44, Pages: 188-195, ISSN: 1525-4135
  • Author Web Link
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  • Citations: 26
• Journal article
  Bottomley C, Isham V, Basanez M-G, 2007,

  Population biology of multispecies helminth infection:: Competition and coexistence

  , JOURNAL OF THEORETICAL BIOLOGY, Vol: 244, Pages: 81-95, ISSN: 0022-5193
  • Author Web Link
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  • Citations: 12

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