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• Journal article
  Anderson RM, 1998,

  Tuberculosis: Old problems and new approaches

  , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 95, Pages: 13352-13354, ISSN: 0027-8424
  • Cite
  • Citations: 10
• Journal article
  Brant SR, Fu YF, Fields CT, Baltazar R, Ravenhill G, Pickles MR, Rohal PM, Mann J, Kirschner BS, Jabs EW, Bayless TM, Hanauer SB, Cho JHet al., 1998,

  American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12

  , GASTROENTEROLOGY, Vol: 115, Pages: 1056-1061, ISSN: 0016-5085
  • Author Web Link
  • Cite
  • Citations: 115
• Journal article
  Day S, Ward H, Ghani A, Bell G, Goan U, Parker M, Claydon E, Ison C, Kinghorn G, Weber Jet al., 1998,

  Sexual histories, partnerships and networks associated with the transmission of gonorrhoea

  , INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 9, Pages: 666-671, ISSN: 0956-4624
  • Cite
  • Citations: 22
• Journal article
  Rodriguez-Moran P, Kelly C, Williams TM, Hjelle Bet al., 1998,

  Hantavirus infection in the Four Corners region of USA in 1998

  , LANCET, Vol: 352, Pages: 1353-1353, ISSN: 0140-6736
  • Cite
  • Citations: 6
• Journal article
  Whittaker CA, Desimone DW, 1998,

  Molecular cloning and developmental expression of the Xenopus homolog of integrin alpha 4.

  , Ann N Y Acad Sci, Vol: 857, Pages: 56-73, ISSN: 0077-8923

  Integrin receptors containing an alpha 4 subunit mediate cell-cell adhesion by binding to VCAM and MadCAM-1 in addition to supporting cell-extracellular matrix (ECM) adhesion by binding to the alternatively spliced V-region of fibronectin (FN). Studies in chick and mouse embryos have implicated these integrins in neural crest migration, myotube formation, heart development, and placentation. Because integrin-FN adhesive interactions have been shown to play essential roles in mammalian development, studies were initiated of integrin alpha 4 in amphibian embryos, which are better suited to experimental analyses of the earliest stages of embryogenesis. Here, the cDNA cloning and pattern of expression of the Xenopus laevis homolog of integrin alpha 4 is reported. Xenopus alpha 4 is 55% identical at the amino-acid level to both its human and mouse counterparts, including conservation of an alpha 4-specific protease cleavage site, 11 potential N-linked glycosylation sites, and 24 cysteine residues. In situ hybridization analysis reveals that transcripts encoding alpha 4 are expressed in epidermis and the branchial arches. Although alpha 4 transcripts can be detected as early as gastrulation, the protein is observed only after tailbud stages of development and is spatially restricted to the epidermis and gills of tadpole stage embryos. From these data it is concluded that Xenopus integrin alpha 4 has structural features in common with other vertebrate alpha 4 homologs, but is detected in a more restricted tissue distribution during development than alpha 4 in other species.

  • Abstract
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• Journal article
  Gregson S, Machekano R, Donnelly CA, Mbizvo MT, Anderson RM, Katzenstein DAet al., 1998,

  Estimating HIV incidence from age-specific prevalence data: comparison with concurrent cohort estimates in a study of male factory workers, Harare, Zimbabwe

  , AIDS, Vol: 12, Pages: 2049-2058, ISSN: 0269-9370
  • Cite
  • Citations: 19
• Journal article
  Austin DJ, White NJ, Anderson RM, 1998,

  The dynamics of drug action on the within-host population growth of infectious agents: Melding pharmacokinetics with pathogen population dynamics

  , JOURNAL OF THEORETICAL BIOLOGY, Vol: 194, Pages: 313-339, ISSN: 0022-5193
  • Cite
  • Citations: 81
• Journal article
  Grassly NC, Xiang Z, Ariyoshi K, Aaby P, Jensen H, van der Loeff MS, Dias F, Whittle H, Breuer Jet al., 1998,

  Mortality among human immunodeficiency virus type 2-positive villagers in rural Guinea-Bissau is correlated with viral genotype

  , JOURNAL OF VIROLOGY, Vol: 72, Pages: 7895-7899, ISSN: 0022-538X
  • Author Web Link
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  • Citations: 19
• Journal article
  Ghani AC, Donnelly CA, Garnett GP, 1998,

  Sampling biases and missing data in explorations of sexual partner networks for the spread of sexually transmitted diseases

  , Statistics in Medicine, Vol: 17, Pages: 2079-2097, ISSN: 0277-6715

  The structures of sexual partner networks are important in determining patterns of transmission of STDs including HIV. Empirical data on sexual partnerships and sexual partner networks collected through sampling individuals are a non-random sample of partnerships and network structures even if individuals are sampled randomly. This has the potential to bias estimates of measures describing the sexual partner network. In addition, biases may be introduced through non-response and missing data. Using Monte Carlo simulation, we investigate the biases that are introduced in estimated measures of the sexual partner network through three common sampling methods. The results indicate that substantial systematic biases are introduced. The direction and magnitude of these biases suggest that, by ignoring them, the risk for the establishment and persistence of infection in a population may be underestimated.

  • Abstract
  • Cite
  • Citations: 84
• Journal article
  Ghani AC, Donnelly CA, Garnett GP, 1998,

  Sampling biases and missing data in explorations of sexual partner networks for the spread of sexually transmitted diseases

  , STATISTICS IN MEDICINE, Vol: 17, Pages: 2079-2097, ISSN: 0277-6715
  • Author Web Link
  • Cite
  • Citations: 74

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