@article{Citarella:2024:10.1016/j.heliyon.2024.e29591,
author = {Citarella, BW and Kartsonaki, C and Ibáñez-Prada, ED and Gonçalves, BP and Baruch, J and Escher, M and Pritchard, MG and Wei, J and Philippy, F and Dagens, A and Hall, M and Lee, J and Kutsogiannis, DJ and Wils, EJ and Fernandes, MA and Tirupakuzhi, Vijayaraghavan BK and Panda, PK and Martin-Loeches, I and Ohshimo, S and Fatoni, AZ and Horby, P and Dunning, J and Rello, J and Merson, L and Rojek, A and Vaillant, M and Olliaro, P and Reyes, LF and Moharam, SA and Abdalasalam, S and Abdalhadi, AA and Abdalla, NR and Abdalla, W and Abdalrheem, AH and Abdalsalam, A and Abdeewi, S and Abdelgaum, EH and Abdelhalim, M and Abdelkabir, M and Abdelrahman, I and Abdukahil, SA and Abdulbaqi, LA and Abdulhamid, S and Abdulhamid, W and Abdulkadir, NN and Abdulwahed, E and Abdunabi, R and Abe, R and Abel, L and Abodina, AM and Abrous, A and Absil, L and Jabal, KA and Salah, NA and Abusalama, A and Abuzaid, TA and Acharya, S and Acker, A and Adam, E and Adem, S and Ademnou, M and Adewhajah, F and Adri},
doi = {10.1016/j.heliyon.2024.e29591},
journal = {Heliyon},
title = {Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms},
url = {http://dx.doi.org/10.1016/j.heliyon.2024.e29591},
volume = {10},
year = {2024}
}

Download

TY  - JOUR
AB  - Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83–0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders.
AU  - Citarella,BW
AU  - Kartsonaki,C
AU  - Ibáñez-Prada,ED
AU  - Gonçalves,BP
AU  - Baruch,J
AU  - Escher,M
AU  - Pritchard,MG
AU  - Wei,J
AU  - Philippy,F
AU  - Dagens,A
AU  - Hall,M
AU  - Lee,J
AU  - Kutsogiannis,DJ
AU  - Wils,EJ
AU  - Fernandes,MA
AU  - Tirupakuzhi,Vijayaraghavan BK
AU  - Panda,PK
AU  - Martin-Loeches,I
AU  - Ohshimo,S
AU  - Fatoni,AZ
AU  - Horby,P
AU  - Dunning,J
AU  - Rello,J
AU  - Merson,L
AU  - Rojek,A
AU  - Vaillant,M
AU  - Olliaro,P
AU  - Reyes,LF
AU  - Moharam,SA
AU  - Abdalasalam,S
AU  - Abdalhadi,AA
AU  - Abdalla,NR
AU  - Abdalla,W
AU  - Abdalrheem,AH
AU  - Abdalsalam,A
AU  - Abdeewi,S
AU  - Abdelgaum,EH
AU  - Abdelhalim,M
AU  - Abdelkabir,M
AU  - Abdelrahman,I
AU  - Abdukahil,SA
AU  - Abdulbaqi,LA
AU  - Abdulhamid,S
AU  - Abdulhamid,W
AU  - Abdulkadir,NN
AU  - Abdulwahed,E
AU  - Abdunabi,R
AU  - Abe,R
AU  - Abel,L
AU  - Abodina,AM
AU  - Abrous,A
AU  - Absil,L
AU  - Jabal,KA
AU  - Salah,NA
AU  - Abusalama,A
AU  - Abuzaid,TA
AU  - Acharya,S
AU  - Acker,A
AU  - Adam,E
AU  - Adem,S
AU  - Ademnou,M
AU  - Adewhajah,F
AU  - Adrião,D
AU  - Afum-Adjei,Awuah A
AU  - Agbogbatey,M
AU  - Al,Ageel S
AU  - Ahmed,AM
AU  - Ahmed,MM
AU  - Ahmed,S
AU  - Alaraji,ZA
AU  - Elhefnawy,Enan AA
AU  - Ahmed,Khalil RA
AU  - Ahmed,Mohamed Abdelaziz AM
AU  - Ainscough,K
AU  - Airlangga,E
AU  - Aisa,T
AU  - Aisha,A
AU  - Aisha,B
AU  - Hssain,AA
AU  - Tamlihat,YA
AU  - Akimoto,T
AU  - Akmal,E
AU  - Akwani,C
AU  - Al,Qasim E
AU  - Alajeeli,A
AU  - Alali,A
AU  - Alalqam,R
AU  - Alameen,AM
AU  - Al-Aquily,M
AU  - Alaraji,ZA
AU  - Albakry,K
AU  - Albatni,S
AU  - Alberti,A
AU  - Aldabbourosama,O
AU  - Al-dabbous,T
AU  - Aldhalia,A
AU  - Aldoukali,A
AU  - Alegesan,S
AU  - Alessi,M
AU  - Alex,B
DO  - 10.1016/j.heliyon.2024.e29591
PY  - 2024///
SN  - 2405-8440
TI  - Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
T2  - Heliyon
UR  - http://dx.doi.org/10.1016/j.heliyon.2024.e29591
VL  - 10
ER  - 

Download