Citation

BibTex format

@article{Topazian:2025:10.1186/s12936-025-05367-w,
author = {Topazian, H and Charles, G and Schmit, N and Pianella, M and Marshall, J and Kleinschmidt, I and Hauck, K and Ghani, A},
doi = {10.1186/s12936-025-05367-w},
journal = {Malaria Journal},
title = {Estimating the potential impact of surveillance test-and-treat posts to reduce malaria in border regions in sub-Saharan Africa: a modelling study},
url = {http://dx.doi.org/10.1186/s12936-025-05367-w},
volume = {24},
year = {2025}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background:The last malaria cases in near-elimination settings are often found in international border regions due to the presence of hard-to-reach populations, conflict, uneven intervention coverage, and human migration. Test-and-treat border posts are an under-researched form of active case detection used to interrupt transmission chains between countries.Methods:An individual-based, mathematical metapopulation model of Plasmodium falciparum was used to estimate the effectiveness of border screening posts on total cases in malaria-endemic sub-Saharan Africa.Results:The implementation of international border posts across 401 sub-national administrative units would avert a median of 7173 (IQR 1075 to 23,550) cases per unit over a 10 year period and reduce PfPR2-10 by a median of 0.21% (IQR 0.04 to 0.44%).Conclusions:Border posts were most effective in low-transmission settings with high-transmission neighbours. Border posts alone in sub-Saharan Africa will not allow a country to reach elimination, particularly when considering feasibility and acceptability, but could contribute to broader control packages to targeted populations.
AU  - Topazian,H
AU  - Charles,G
AU  - Schmit,N
AU  - Pianella,M
AU  - Marshall,J
AU  - Kleinschmidt,I
AU  - Hauck,K
AU  - Ghani,A
DO  - 10.1186/s12936-025-05367-w
PY  - 2025///
SN  - 1475-2875
TI  - Estimating the potential impact of surveillance test-and-treat posts to reduce malaria in border regions in sub-Saharan Africa: a modelling study
T2  - Malaria Journal
UR  - http://dx.doi.org/10.1186/s12936-025-05367-w
VL  - 24
ER  -
Download

Contact us

For any enquiries related to the MRC Centre please contact:

Scientific Manager
Susannah Fisher
mrc.gida@imperial.ac.uk

External Relationships and Communications Manager
Dr Sabine van Elsland
s.van-elsland@imperial.ac.uk