Closed-loop, personalized brain stimulation intervention for impairment of cognitive control
David Sharp (Medicine)
Nir Grossman (Electronic & Electrical Engineering)
Adam Hampshire (Medicine)
Peter Hellyer (Bioengineering)
Recent advances in temporal interference transcranial alternating current stimulation (TI-TACS) hold much promise for development of non-invasive intervention and cognitive neuroscience research. TI-TACS produces neural stimulation through interference between multiple electric fields and has important experimental advantages. Most notably, it can: (a) target stimulation, including to deep brain structures without affecting overlaying cortex and (b) simultaneously read out and phase lock stimulation to EEG measures of endogenous brain activity. The aim of this project is to determine the utility of TI-TACS in the context of cognitive neuroscience research with humans. The project will focus on advancing our understanding of the brain mechanisms that underlie attentional and motor control of behaviour, which is affected in diverse clinical populations and so has broad clinical relevance.