In this section
@inbook{Barnes:2004:B978-012589762-4/50034-7,
author = {Barnes, PJ},
booktitle = {Primer on the Autonomic Nervous System Second Edition},
doi = {B978-012589762-4/50034-7},
pages = {130--133},
title = {Autonomic Control of Airways},
url = {http://dx.doi.org/10.1016/B978-012589762-4/50034-7},
year = {2004}
}
TY - CHAP
AB - Several neural mechanisms are involved in the regulation of airway caliber, and abnormalities in neural control may contribute to airway narrowing in diseases-such as asthma and chronic obstructive pulmonary disease (COPD)-contributing to the symptoms and possibly to the inflammatory response. Neural mechanisms contribute to the pathophysiology of asthma in several ways. Several triggers activate reflex cholinergic bronchoconstriction and the cough reflex may be sensitized by inflammatory mediators, including neurotrophins. The roles of neurogenic inflammation and neuropeptides, however, remain uncertain. The structural narrowing of the airways in COPD means that the normal vagal cholinergic tone has a relatively greater effect on caliber than in normal airways for geometric reasons. Cholinergic mechanisms are the only reversible component of COPD and may contribute to the mucus hypersecretion of chronic bronchitis.
AU - Barnes,PJ
DO - B978-012589762-4/50034-7
EP - 133
PY - 2004///
SP - 130
TI - Autonomic Control of Airways
T1 - Primer on the Autonomic Nervous System Second Edition
UR - http://dx.doi.org/10.1016/B978-012589762-4/50034-7
ER -