Browse through all publications from the Institute of Global Health Innovation, which our Patient Safety Research Collaboration is part of. This feed includes reports and research papers from our Centre. 


BibTex format

author = {Elliott, P and Bodinier, B and Eales, O and Wang, H and Haw, D and Elliott, J and Whitaker, M and Jonnerby, J and Tang, D and Walters, CE and Atchison, C and Diggle, PJ and Page, AJ and Trotter, AJ and Ashby, D and Barclay, W and Taylor, G and Ward, H and Darzi, A and Cooke, GS and Chadeau-Hyam, M and Donnelly, CA},
doi = {10.1126/science.abn8347},
journal = {Science},
pages = {eabn8347--eabn8347},
title = {Rapid increase in Omicron infections in England during December 2021: REACT-1 study.},
url = {},
volume = {375},
year = {2022}

RIS format (EndNote, RefMan)

AB - The unprecedented rise in SARS-CoV-2 infections during December 2021 was concurrent with rapid spread of the Omicron variant in England and globally. We analyzed prevalence of SARS-CoV-2 and its dynamics in England from end November to mid-December 2021 among almost 100,000 participants from the REACT-1 study. Prevalence was high with rapid growth nationally and particularly in London during December 2021, and an increasing proportion of infections due to Omicron. We observed large falls in swab positivity among mostly vaccinated older children (12-17 years) compared with unvaccinated younger children (5-11 years), and in adults who received a third (booster) vaccine dose vs. two doses. Our results reinforce the importance of vaccination and booster campaigns, although additional measures have been needed to control the rapid growth of the Omicron variant.
AU - Elliott,P
AU - Bodinier,B
AU - Eales,O
AU - Wang,H
AU - Haw,D
AU - Elliott,J
AU - Whitaker,M
AU - Jonnerby,J
AU - Tang,D
AU - Walters,CE
AU - Atchison,C
AU - Diggle,PJ
AU - Page,AJ
AU - Trotter,AJ
AU - Ashby,D
AU - Barclay,W
AU - Taylor,G
AU - Ward,H
AU - Darzi,A
AU - Cooke,GS
AU - Chadeau-Hyam,M
AU - Donnelly,CA
DO - 10.1126/science.abn8347
EP - 8347
PY - 2022///
SN - 0036-8075
SP - 8347
TI - Rapid increase in Omicron infections in England during December 2021: REACT-1 study.
T2 - Science
UR -
UR -
UR -
UR -
VL - 375
ER -