Imperial College London

ALI REZA ABDOLRASOULI

Faculty of MedicineDepartment of Infectious Disease

Honorary Research Fellow
 
 
 
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Contact

 

a.abdolrasouli

 
 
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Location

 

Flowers buildingSouth Kensington Campus

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Summary

 

RESEARCH INTERESTS

  • Laboratory diagnosis of invasive fungal infections
  • Emerging human fungal pathogens
  • Azole-resistance in Aspergillus fumigatus
  • Applications of whole genome sequencing in diagnostic mycology

Collaborations

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  • Professor Thomas R. Rogers, Trinity College Dublin, Ireland
  • Professor Elizabeth M. Johnson, Public Health England, UK
  • Professor Andrew M. Borman, Public Health England, UK
  • Dr P. Lewis white, Public Health Wales, UK
  • Dr Ferry Hagen, Westerdijke Fungal Biodiversity Institute, Netherlands
  • Professor Jacques F. Meise, Radboud University Medical Centre, Netherlands 

SELECTED PUBLICATIONS

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  1. Rudramurthy SM, Colley T, AbdolrasouliA, Ashman J, Dhaliwal M, Kaur H, Armstrong-James D, Strong P, Rapeport G, Schelenz S, Ito K, Chakrabarti A. In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris. J Antimicrob Chemother. 2019;74(10):2943-2949
  2. Noy ML, Abdolrasouli A, Borman AM, Fraser M, Francis N, Moore LSP, Merika EE. Cutaneotrichosporon (Trichosporon) debeurmannianum associated with a subcutaneous mycotic cyst successfully treated with voriconazole. Clin Exp Dermatol. 2019 Jul 22. doi: 10.1111/ced.14037. [Epub ahead of print]
  3.  Howlett S, Sullivan T, Abdolrasouli A, Borman AM, Johnson EM, Lewis P, Baheerathan A, Davies F, Sanderson F, Davies N, Singh-Curry V. A black mould death: A case of fatal cerebral phaeohyphomycosis caused by Cladophialophora bantianaMed Mycol Case Rep. 2019; 28(24):23-26
  4. Abdolrasouli A, Petrou MA, Park H, Rhodes JL, Rawson TM, Moore LSP, Donaldson H, Holmes AH, Fisher MC, Armstrong-James D. Surveillance for azole-resistant Aspergillus fumigatus in a centralized diagnostic mycology service, London, United Kingdom, 1998–2017. Front Microbiol. 2018;9:2234.
  5. Abdolrasouli A, Scourfield A, Rhodes J, Shah A, Elborn JS, Fisher MC, Schelenz S, Armstrong-James D. High prevalence of triazole resistance in clinical Aspergillus fumigatus isolates in a specialist cardio-thoracic centre. Int J Antimicrob Agents. 2018;52(5):637-642.
  6. Abdolrasouli A, Bercusson AC, Rhodes JL, Hagen F, Buil JB, Tang AYY, de Boer LL, Shah A, Milburn AJ, Elborn JS, Jones AL, Meis JF, Fisher MC, Schelenz S, Simmonds NJ, Armstrong-James D. Mycoses. 2018;61(9):665-673.
  7. Nash A, Sewell T, Farrer RA, Abdolrasouli A, Shelton JMG, Fisher MC, Rhodes J. MARDy: Mycology Antifungal Resistance Database. Bioinformatics. 2018;34(18):3233-3234.
  8. Rhodes J, AbdolrasouliA, Farrer RA, Cuomo CA, Aanensen DM, Armstrong-James D, Fisher MC, Schelenz S. Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris. Emerg Microbes Infect. 2018;7(1):43.
  9. AbdolrasouliA, Armstrong-James D, Ryan L, Schelenz S. In vitro efficacy of disinfectants utilised for skin decolonisation and environmental decontamination during a hospital outbreak with Candida auris. Mycoses 2017;60(11):758-763
  10. Amarsaikhan N, Sands EM, Shah A, AbdolrasouliA, Reed A, Slaven JE, Armstrong-James D, Templeton SP. Caspofungin Increases Fungal Chitin and Eosinophil and γδ T Cell-Dependent Pathology in Invasive Aspergillosis. J Immunol  2017;199(2):624-632.
  11. Cameron SJ, Bolt F, Perdones-Montero A, Rickards T, Hardiman K, Abdolrasouli A, Burke A, Bodai Z, Karancsi T, Simon D, Schaffer R, Rebec M, Balog J, Takáts Z. Rapid evaporative ionisation mass spectrometry (REIMS) provides accurate direct from culture species identification within the genus Candida. Sci Rep 2016;6:36788.
  12. Schelenz S, Hagen F, Rhodes JL, Abdolrasouli A, Chowdhary A, Hall A, Ryan L, Shackleton J, Trimlett R, Meis JF, Armstrong-James D, Fisher MC. First hospital outbreak of the globally emerging Candida auris in a European hospital. Antimicrob Resist Infect Control 2016;5:35.
  13. Abdolrasouli A, Gonzalo X, Jatan A, McArthur GJ, Francis N, Azadian BS, Borman AM, Johnson EM. Subcutaneous phaeohyphomycosit cyst associated with Medicopsis romeroi in an immunocompromised host. Mycopathologia. 2016 ;181(9-10):717-21.
  14. Abdolrasouli A, Rhodes JL, Beale MA, Hagen F, Rogers TR, Chowdhary A, Meis JA, Armstrong-James D, Fisher MC. Genomic context of azole resistance mutations in Aspergillus fumigatus determined using whole-genome sequencing. mBio 2015; 6(3):e00536-15.
  15. Bidula S, Sexton DW, Yates M, Abdolrasouli A, Shah A, Wallis R, Reed A, Armstrong-James D, Schelenz S. H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses. Immunology 2015; 146: 281-291.
  16. Bidula S, Sexton DW, Abdolrasouli A, Shah A, Reed A, Armstrong-James D, Schelenz S. Serum opsonin, L-ficolin, is detected in human lungs of transplant patients following fungal infections and modulates inflammation and killing of A. fumigatus. J Infect Dis. 2015; 212: 234-246.
  17. Fatania N, Fraser M, Savage M, Hart J, AbdolrasouliA. Comparative evaluation of matrix-assisted laser desorption ionisation-time of flight mass spectrometry and conventional phenotypic-based methods for identification of clinically important yeasts in a UK-based medical microbiology laboratory. J Clin Pathol 2015;68:1040-2.
  18. Jarvis S, Ind PW, Thomas CP, Goonesekera S, Haffenden R, Abdolrasouli A, Robert J Shiner. Microbial contamination of domiciliary nebulisers and clinical implications in chronic obstructive pulmonary disease. BMJ Open Resp Res. 2014 Feb 27;1(1):e000018.
  19. Abdolrasouli A, Croucher A, Roushan A. Bilateral conjunctivitis due to Trichomonas vaginalis without genital infection: an unusual presentation in an adult man. J Clin Microbiol 2013;51:3157-3159.
  20. Abdolrasouli A, Croucher A, Hemmati Y, Mabey D. A case of endemic syphilis in Iran. Emerg Infect Dis 2013;19:162-163.