Imperial College London


Faculty of MedicineNational Heart & Lung Institute




+44 (0)20 7594 7940a.amaral Website




G48Emmanuel Kaye BuildingRoyal Brompton Campus





Dr Amaral is an epidemiologist at the National Heart and Lung Institute, where he leads a research group whose work focuses on understanding the causes of poor lung function and chronic lung disease in populations around the globe. He is also interested in the mechanisms underlying differences in lung function across ethnic groups and multimorbidity associated with poor lung function. His goal is to contribute to the prevention of chronic lung disease and reduction of mortality worldwide.

Dr Amaral is the Project Lead of the multinational Burden of Obstructive Lung Disease (BOLD) cohort study.

#GlobalHealth   #LungHealth   #ChronicLungDisease   #COPD  #SmallAirwaysObstruction   #SmallLungs 

Blog Posts

Highlights of Dr Amaral's research group can be found in the Global Respiratory Health blog.

Invited blog posts:

COPD - Son of a TB. Blog: Institute of Global Health Innovation; 17 June 2016.

Scientists question the role of solid fuels in common lung disease. Blog: The Surg; 17 September 2017.

Unravelling the mystery of smaller lungs in low- and middle-income countries. Blog: Imperial Medicine; 26 January 2024.


Chronic airflow obstruction and solid fuels: BOLD study

Selected Publications

Journal Articles

Knox-Brown B, Patel J, Potts J, et al., 2023, The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: Results from the Burden of Obstructive Lung Disease (BOLD) study, Respiratory Research, Vol:24, ISSN:1465-9921

Feary J, Quintero Santofimio V, Potts J, et al., 2023, Occupational exposures and small airways obstruction in the UK Biobank Cohort, Erj Open Research, Vol:9, ISSN:2312-0541, Pages:1-9

Knox-Brown B, Patel J, Potts J, et al., 2023, Small airways obstruction and its risk factors in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study, The Lancet Global Health, Vol:11, ISSN:2214-109X, Pages:e69-e82

Amaral AFS, Patel J, Kato BS, et al., 2018, Airflow Obstruction and Use of Solid Fuels for Cooking or Heating BOLD (Burden of Obstructive Lung Disease) Results, American Journal of Respiratory and Critical Care Medicine, Vol:197, ISSN:1073-449X, Pages:595-610

Amaral AFS, Strachan DP, Burney PGJ, et al., 2017, Female Smokers Are at Greater Risk of Airflow Obstruction Than Male Smokers UK Biobank, American Journal of Respiratory and Critical Care Medicine, Vol:195, ISSN:1073-449X, Pages:1226-1235

Amaral AFS, Patel J, Gnatiuc L, et al., 2015, Association of pulse wave velocity with total lung capacity: A cross-sectional analysis of the BOLD London study, Respiratory Medicine, Vol:109, ISSN:0954-6111, Pages:1569-1575

Amaral AFS, Coton S, Kato B, et al., 2015, Tuberculosis associates with both airflow obstruction and low lung function: BOLD results, European Respiratory Journal, Vol:46, ISSN:0903-1936, Pages:1104-1112

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